Aliases for SCHLAP1 Gene

Subcategory (RNA class) for SCHLAP1 Gene

lncRNA

Number of RNA Genes sources:

4 / 14

Aliases for SCHLAP1 Gene

  • SWI/SNF Complex Antagonist Associated With Prostate Cancer 1 2 3 5
  • SWI/SNF Complex Antagonist Associated With Prostate Cancer 1 (Non-Protein Coding) 2 3
  • Second Chromosome Locus Associated With Prostate 1 2 3
  • Long Intergenic Non-Protein Coding RNA 913 2 3
  • Prostate Cancer Associated Transcript 11 2 3
  • SCHLAP1 2 168
  • NONHSAG029985 92
  • HSALNG0020769 167
  • LINC00913 3
  • PCAT114 3
  • PCAT11 3

External Ids for SCHLAP1 Gene

Previous HGNC Symbols for SCHLAP1 Gene

  • LINC00913

Previous GeneCards Identifiers for SCHLAP1 Gene

  • GC02U903022

Summaries for SCHLAP1 Gene

GeneCards Summary for SCHLAP1 Gene

SCHLAP1 (SWI/SNF Complex Antagonist Associated With Prostate Cancer 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with SCHLAP1 include Prostate Disease and Prostate Cancer.

Additional gene information for SCHLAP1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SCHLAP1 Gene

Genomics for SCHLAP1 Gene

GeneHancer (GH) Regulatory Elements for SCHLAP1 Gene

Promoters and enhancers for SCHLAP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J180676 Enhancer 0.7 Ensembl ENCODE 500.7 -0.3 -302 2.2 NR2F2 ZBTB33 JUND RAD21 RXRA MAX HNF4A REST YY1 HNF4G SCHLAP1 ENSG00000225258 piR-48222-195
GH02J180679 Enhancer 0.5 Ensembl 500.7 +1.8 1799 1.6 EP300 TEAD4 SAP30 HDAC2 SIN3A SMARCA4 CTBP2 POLR2A MAX SCHLAP1 piR-46847-134 ENSG00000225258
GH02J180691 Promoter 0.8 Ensembl 0.4 +14.2 14198 0.8 NCOR1 POLR2G GTF2A2 POLR2H SUPT5H ZFP91 SMAD5 MEIS2 POLR2A ELF4 ENSG00000225258 piR-46847-134 SCHLAP1
GH02J180707 Enhancer 0.9 Ensembl ENCODE 0.3 +28.8 28799 3.6 FOS ZNF316 NFIC CEBPG NR3C1 FOSL2 CEBPB JUN USF1 FOSL1 ENSG00000225258 LOC105373771 SCHLAP1
GH02J180655 Enhancer 0.8 Ensembl ENCODE 0.4 -21.5 -21500 2.2 CTCF TCF12 JUND FOS OSR2 CREB1 ZNF184 FOSL2 CEBPB JUN SCHLAP1 ENSG00000225258 piR-48222-195
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SCHLAP1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SCHLAP1 Gene

Genomic Locations for SCHLAP1 Gene
chr2:180,678,002-180,921,247
(GRCh38/hg38)
Size:
243,246 bases
Orientation:
Plus strand

Genomic View for SCHLAP1 Gene

Genes around SCHLAP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SCHLAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SCHLAP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SCHLAP1 Gene

Proteins for SCHLAP1 Gene

Post-translational modifications for SCHLAP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SCHLAP1 Gene

Domains & Families for SCHLAP1 Gene

Gene Families for SCHLAP1 Gene

genes like me logo Genes that share domains with SCHLAP1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SCHLAP1 Gene

Function for SCHLAP1 Gene

Phenotypes From GWAS Catalog for SCHLAP1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SCHLAP1 Gene

Localization for SCHLAP1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SCHLAP1 gene
Compartment Confidence
nucleus 2
plasma membrane 1
extracellular 1
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SCHLAP1 Gene

Pathways & Interactions for SCHLAP1 Gene

PathCards logo

SuperPathways for SCHLAP1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for SCHLAP1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SCHLAP1 Gene

Drugs & Compounds for SCHLAP1 Gene

No Compound Related Data Available

Transcripts for SCHLAP1 Gene

mRNA/cDNA for SCHLAP1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for SCHLAP1 Gene

No ASD Table

Relevant External Links for SCHLAP1 Gene

GeneLoc Exon Structure for
SCHLAP1

Expression for SCHLAP1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SCHLAP1

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SCHLAP1 Gene

Orthologs for SCHLAP1 Gene

Evolution for SCHLAP1 Gene

ENSEMBL:
Gene Tree for SCHLAP1 (if available)
TreeFam:
Gene Tree for SCHLAP1 (if available)

No data available for Orthologs for SCHLAP1 Gene

Paralogs for SCHLAP1 Gene

No data available for Paralogs for SCHLAP1 Gene

Variants for SCHLAP1 Gene

Additional dbSNP identifiers (rs#s) for SCHLAP1 Gene

Structural Variations from Database of Genomic Variants (DGV) for SCHLAP1 Gene

Variant ID Type Subtype PubMed ID
esv1004332 CNV deletion 20482838
esv1505605 CNV deletion 17803354
esv1564115 CNV insertion 17803354
esv1567921 CNV deletion 17803354
esv3364161 CNV duplication 20981092
esv3893513 CNV loss 25118596
nsv1072053 CNV deletion 25765185
nsv1077898 CNV duplication 25765185
nsv1114151 CNV deletion 24896259
nsv1115584 CNV duplication 24896259
nsv1138870 CNV deletion 24896259
nsv821835 CNV gain 20364138
nsv834475 CNV gain 17160897
nsv963752 CNV duplication 23825009

Additional Variant Information for SCHLAP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SCHLAP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SCHLAP1 Gene

Disorders for SCHLAP1 Gene

MalaCards: The human disease database

(4) MalaCards diseases for SCHLAP1 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
prostate disease
  • prostate diseases
prostate cancer
  • prostate cancer, somatic
bladder cancer
  • bladder cancer, somatic
renal cell carcinoma, nonpapillary
  • rcc
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SCHLAP1

genes like me logo Genes that share disorders with SCHLAP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SCHLAP1 Gene

Publications for SCHLAP1 Gene

  1. The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex. (PMID: 24076601) Prensner JR … Chinnaiyan AM (Nature genetics 2013) 2 3 54
  2. Linking the SWI/SNF complex to prostate cancer. (PMID: 24165726) Lee RS … Roberts CW (Nature genetics 2013) 2 3 54
  3. SWI/SNF remains localized to chromatin in the presence of SCHLAP1. (PMID: 30510238) Raab JR … Magnuson T (Nature genetics 2019) 3 54
  4. Long Noncoding RNA SChLAP1 Accelerates the Proliferation and Metastasis of Prostate Cancer via Targeting miR-198 and Promoting the MAPK1 Pathway. (PMID: 28492138) Li Y … Wang S (Oncology research 2018) 3 54
  5. A Prostate Cancer "Nimbosus": Genomic Instability and SChLAP1 Dysregulation Underpin Aggression of Intraductal and Cribriform Subpathologies. (PMID: 28511883) Chua MLK … Bristow RG (European urology 2017) 3 54

Products for SCHLAP1 Gene

Sources for SCHLAP1 Gene