Aliases for SCRT1 Gene
External Ids for SCRT1 Gene
Previous GeneCards Identifiers for SCRT1 Gene
This gene encodes a C2H2-type zinc finger transcriptional repressor that binds to E-box motifs. The encoded protein may promote neural differention and may be involved in cancers with neuroendocrine features. [provided by RefSeq, Jul 2013]
GeneCards Summary for SCRT1 Gene
SCRT1 (Scratch Family Transcriptional Repressor 1) is a Protein Coding gene. Diseases associated with SCRT1 include Pineal Region Meningioma and Extrahepatic Bile Duct Adenocarcinoma. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is SCRT2.
UniProtKB/Swiss-Prot Summary for SCRT1 Gene
Transcriptional repressor that binds E-box motif CAGGTG. Can modulate the action of basic helix-loop-helix (bHLH) transcription factors, critical for neuronal differentiation.