Aliases for SCML2 Gene
External Ids for SCML2 Gene
Previous GeneCards Identifiers for SCML2 Gene
This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq, Jun 2010]
GeneCards Summary for SCML2 Gene
SCML2 (Scm Polycomb Group Protein Like 2) is a Protein Coding gene. Diseases associated with SCML2 include Retinitis Pigmentosa 24 and Central Nervous System Mesenchymal Non-Meningothelial Tumor. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is SCMH1.
UniProtKB/Swiss-Prot Summary for SCML2 Gene
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).