Aliases for SCLY Gene
External Ids for SCLY Gene
Previous GeneCards Identifiers for SCLY Gene
Selenocysteine lyase (SCLY; EC 188.8.131.52) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SCLY Gene
SCLY (Selenocysteine Lyase) is a Protein Coding gene. Diseases associated with SCLY include Somatization Disorder and Dependent Personality Disorder. Among its related pathways are Viral mRNA Translation and Selenocompound metabolism. Gene Ontology (GO) annotations related to this gene include transferase activity and lyase activity. An important paralog of this gene is NFS1.
UniProtKB/Swiss-Prot Summary for SCLY Gene
Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.