Aliases for SCIMP Gene
External Ids for SCIMP Gene
Previous HGNC Symbols for SCIMP Gene
Previous GeneCards Identifiers for SCIMP Gene
This gene encodes a transmembrane adaptor protein that is expressed in antigen-presenting cells and is localized in the immunologic synapse. The encoded protein is involved in major histocompatibility complex class II signal transduction and immune synapse formation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
GeneCards Summary for SCIMP Gene
SCIMP (SLP Adaptor And CSK Interacting Membrane Protein) is a Protein Coding gene. An important paralog of this gene is MEI1.
UniProtKB/Swiss-Prot Summary for SCIMP Gene
Lipid tetraspanin-associated transmembrane adapter/mediator involved in major histocompatibility complex (MHC) class II signaling transduction. Required in generating the calcium response and enhancing ERK activity upon MHC-II stimulation.