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The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin... See more...
Aliases for SCG2 Gene
Aliases for SCG2 Gene
External Ids for SCG2 Gene
- HGNC: 10575
- Entrez Gene: 7857
- Ensembl: ENSG00000171951
- OMIM: 118930
- UniProtKB: P13521
Previous GeneCards Identifiers for SCG2 Gene
- GC02M222484
- GC02M223182
- GC02M224425
- GC02M224664
- GC02M224287
- GC02M224169
- GC02M216313
Summaries for SCG2 Gene
-
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008]
GeneCards Summary for SCG2 Gene
SCG2 (Secretogranin II) is a Protein Coding gene. Diseases associated with SCG2 include Collagenous Colitis and Intracranial Primitive Neuroectodermal Tumor. Gene Ontology (GO) annotations related to this gene include cytokine activity and chemoattractant activity.
UniProtKB/Swiss-Prot Summary for SCG2 Gene
-
Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
Additional gene information for SCG2 Gene
- HGNC(10575)
- Entrez Gene(7857)
- Ensembl(ENSG00000171951)
- OMIM(118930)
- UniProtKB(P13521)
- Open Targets Platform(ENSG00000171951)
- Search for SCG2 at DataMed
- Search for SCG2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SCG2 Gene
Genomics for SCG2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SCG2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH02J223598 | Promoter/Enhancer | 1.5 | EPDnew Ensembl ENCODE | 600.7 | +2.0 | 2024 | 4.2 | CREB1 ATF7 ZNF629 REST TFE3 CTCF JUND POLR2A RXRB IRF2 | SCG2 piR-31292-109 KCNE4 | |
| GH02J223603 | Enhancer | 0.5 | FANTOM5 Ensembl | 618 | -0.8 | -782 | 0.3 | CEBPB | SCG2 lnc-MRPL44-4 AP1S3 | |
| GH02J223956 | Promoter/Enhancer | 2.1 | EPDnew Ensembl ENCODE CraniofacialAtlas | 9.7 | -355.7 | -355684 | 3.9 | ZNF221 SP1 HNRNPL GATAD2A TEAD4 PRDM10 ZNF629 TFE3 SIX5 LEF1 | MRPL44 lnc-WDFY1-4 piR-41482 WDFY1 ANKRD49P1 SCG2 SERPINE2 | |
| GH02J224483 | Enhancer | 1.1 | Ensembl ENCODE | 10.5 | -882.8 | -882840 | 4 | HNRNPL GATAD2A TEAD4 PRDM10 TFE3 LEF1 NFKBIZ RCOR2 FOXA1 ZIC2 | lnc-FAM124B-1 ANKRD49P1 SCG2 CUL3 ENSG00000274629 FAM124B | |
| GH02J223587 | Enhancer | 0.6 | FANTOM5 Ensembl | 4.8 | +14.1 | 14060 | 1.4 | ATF7 USF1 ATF2 | SCG2 piR-31292-109 HSALNG0022585 KCNE4 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SCG2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SCG2
- Top Transcription factor binding sites by QIAGEN in the SCG2 gene promoter:
-
- AP-1
- Nkx2-5
- Nkx3-1
- Nkx3-1 v1
- Nkx3-1 v2
- Nkx3-1 v3
- Nkx3-1 v4
- POU3F2
- RSRFC4
- S8
Genomic Locations for SCG2 Gene
Genomic Locations for SCG2 Gene
- chr2:223,596,940-223,602,361
- (GRCh38/hg38)
- Size:
- 5,422 bases
- Orientation:
- Minus strand
- chr2:224,461,658-224,467,221
- (GRCh37/hg19)
- Size:
- 5,564 bases
- Orientation:
- Minus strand
Genomic View for SCG2 Gene
Genes around SCG2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q36.1 by HGNC
- 2q36.1 by Entrez Gene
- 2q36.1 by Ensembl
SCG2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SCG2 Gene
Proteins for SCG2 Gene
-
Protein details for SCG2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P13521-SCG2_HUMAN
- Recommended name:
- Secretogranin-2
- Protein Accession:
- P13521
- B2R662
- Q53T11
- Q8TBH3
Protein attributes for SCG2 Gene
- Size:
- 617 amino acids
- Molecular mass:
- 70941 Da
- Quaternary structure:
-
- Interacts with Secretogranin III/SCG3.
- Miscellaneous:
-
- Binds calcium with a low-affinity.
Protein Expression for SCG2 Gene
Post-translational modifications for SCG2 Gene
- O-glycosylated.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for SCG2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences SCG2 / Secretogranin II Antibody (LS-B9817) and SCG2 / Secretogranin II Antibody (LS-B10869)
- Novus Biologicals Antibodies for SCG2
- Invitrogen Antibodies for SCG2 (AFLGC-SCG2)
-
Boster Bio Antibodies for SCG2
- Sino Biological Antibodies for SCG2
Protein Products
- G Biosciences Human SCG2/Secretogranin-2, Lyophilized
- Search Origene for MassSpec and Protein Over-expression Lysates for SCG2
- Origene Custom Protein Services for SCG2
- Sino Biological Cell Lysates for SCG2
- Sino Biological Recombinant Proteins for SCG2
-
ProSci Proteins for SCG2
-
Abcam proteins for SCG2
Assay Products
- G Biosciences Immunotag™ Secretogranin-2 ELISA Kit
- Novus Biologicals ELISA Kits for SCG2
No data available for DME Specific Peptides for SCG2 Gene
Domains & Families for SCG2 Gene
Gene Families for SCG2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted secreted proteins
Protein Domains for SCG2 Gene
- InterPro:
- Blocks:
-
- Chromogranin/secretogranin
- ProtoNet:
Suggested Antigen Peptide Sequences for SCG2 Gene
- GenScript: Design optimal peptide antigens:
-
- Secretogranin II (SCG2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P13521- Family:
-
- Belongs to the chromogranin/secretogranin protein family.
Function for SCG2 Gene
Molecular function for SCG2 Gene
- UniProtKB/Swiss-Prot Function:
- Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
- GENATLAS Biochemistry:
- chromogranin C
Phenotypes From GWAS Catalog for SCG2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005125 | cytokine activity | IDA | 14970115 |
| GO:0005515 | protein binding | IPI | 21516116 |
| GO:0042056 | chemoattractant activity | IDA | 9473216 |
Phenotypes for SCG2 Gene
- MGI mutant phenotypes for SCG2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SCG2:
Animal Models for SCG2 Gene
- MGI Knock Outs for SCG2:
-
- Scg2 Scg2<tm1.1(KOMP)Vlcg>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SCG2 - Select products 50% OFF >
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OriGene CRISPR knockouts for SCG2
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-
Santa Cruz Biotechnology (SCBT) CRISPR for SCG2
miRNA for SCG2 Gene
- miRTarBase miRNAs that target SCG2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SCG2
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Clone Products
- Applied Biological Materials (abm): Clones for SCG2 - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for SCG2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SCG2
Cell Line Products
-
Horizon Cell Lines for SCG2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SCG2 Gene
Localization for SCG2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SCG2 Gene
- Secreted. Note=Neuroendocrine and endocrine secretory granules.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| endoplasmic reticulum | 4 |
| nucleus | 3 |
| plasma membrane | 2 |
| cytoskeleton | 2 |
| golgi apparatus | 2 |
| mitochondrion | 1 |
| endosome | 1 |
| cytosol | 1 |
| lysosome | 1 |
- Golgi apparatus (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005615 | extracellular space | IDA | 9473216 |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
| GO:0030141 | secretory granule | IEA,IBA | 21873635 |
| GO:0031045 | dense core granule | IEA | -- |
Pathways & Interactions for SCG2 Gene
Interacting Proteins for SCG2 Gene
Selected Interacting proteins:
P13521-SCG2_HUMAN
ENSP00000304133
for SCG2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for SCG2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000165 | MAPK cascade | IDA | 14970115 |
| GO:0001525 | angiogenesis | IEA,IDA | 14970115 |
| GO:0001937 | negative regulation of endothelial cell proliferation | TAS | 9473216 |
| GO:0001938 | positive regulation of endothelial cell proliferation | IDA | 14970115 |
| GO:0006954 | inflammatory response | TAS | 14970115 |
No data available for Pathways by source and SIGNOR curated interactions for SCG2 Gene
Drugs & Compounds for SCG2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Calcium | Nutra | 6556 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
- G Biosciences Human SCG2/Secretogranin-2, Lyophilized
Transcripts for SCG2 Gene
mRNA/cDNA for SCG2 Gene
- 1 REFSEQ mRNAs :
- 5 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000305409 2434 nts (view in UCSC)
- ENST00000421386 589 nts (view in UCSC)
- ENST00000433889 544 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SCG2 - Select products 50% OFF >
- * SCG2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SCG2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SCG2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SCG2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SCG2
- Browse OriGene Inhibitory RNA Products For SCG2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SCG2
Clone Products
- Applied Biological Materials (abm): Clones for SCG2 - Select products 50% OFF >
- * SCG2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SCG2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SCG2
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||
| SP2: | - | - | |||||||||||
| SP3: |
Relevant External Links for SCG2 Gene
- GeneLoc Exon Structure for
- SCG2
Expression for SCG2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Neural Tube (Nervous System)
- Brain (Nervous System)
-
Pancreas (Endocrine System)
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
-
Epithelial Cells
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
-
Neurons
- Mature Rod Bipolar Cells Inner Nuclear Layer
- Neuron-like cells(Vierbuchen T et. al. 2010)
- Neural Crest (Gastrulation Derivatives)
-
Epiblast (Early Embryonic Tissues)
- Epiblast Cells Epiblast
-
Eye (Sensory Organs)
- Mature Rod Bipolar Cells Inner Nuclear Layer
- Gut Tube (Gastrointestinal Tract)
- Paraxial Mesoderm (Gastrulation Derivatives)
- Mesoderm (Gastrulation Derivatives)
mRNA differential expression in normal tissues according to GTEx for SCG2 Gene
This gene is overexpressed in Brain - Hypothalamus (x10.4), Brain - Nucleus accumbens (basal ganglia) (x7.8), Pituitary (x6.0), Brain - Caudate (basal ganglia) (x4.4), and Brain - Putamen (basal ganglia) (x4.2).
This gene is overexpressed in Islet of Langerhans (22.7), Cerebrospinal fluid (9.8), Amniocyte (7.9), and Bone marrow stromal cell (7.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SCG2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SCG2
SOURCE GeneReport for Unigene cluster for SCG2 Gene:
Hs.516726Evidence on tissue expression from TISSUES for SCG2 Gene
- Nervous system(5)
- Adrenal gland(3.7)
- Pancreas(3.6)
- Kidney(2.9)
- Intestine(2.4)
- Blood(2.2)
- Heart(2.1)
Primer Products
-
OriGene qPCR primer pairs for SCG2
-
OriGene qPCR primer pairs and template standards for SCG2
Gene Expression Assay Products
No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SCG2 Gene
Orthologs for SCG2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SCG2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SCG2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SCG2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Scg2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Scg2 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | SCG2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SCG2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | SCG2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SCG2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | scg2 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC397939 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | scg2b 30 31 |
|
OneToMany | |
| scg2a 31 |
|
OneToMany |
- Species where no ortholog for SCG2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SCG2 Gene
- ENSEMBL:
- Gene Tree for SCG2 (if available)
- TreeFam:
- Gene Tree for SCG2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SCG2: view image
Paralogs for SCG2 Gene
No data available for Paralogs for SCG2 Gene
Variants for SCG2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SCG2 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 783210 | Benign: not provided | 223,597,489(-) | G/A | SYNONYMOUS_VARIANT | |
| rs1438157 | - | p.Ala196Val | |||
| rs16864976 | - | p.Tyr61His | |||
| rs17852053 | - | p.Asp294Gly | |||
| rs17852054 | - | p.Asp535Gly |
Residual Variation Intolerance Score:
20.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.02;
37.12% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SCG2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SCG2 Gene
Disorders for SCG2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| collagenous colitis |
|
|
| intracranial primitive neuroectodermal tumor |
|
|
| neuroendocrine tumor |
|
|
| pheochromocytoma |
|
|
| neuroendocrine carcinoma |
|
Search SCG2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SCG2
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for SCG2 Gene
Publications for SCG2 Gene
- Dispersion of chromogranin/secretogranin secretory protein family loci in mammalian genomes. (PMID: 8617499) Mahata SK … O'Connor DT (Genomics 1996) 2 3 23
- Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. (PMID: 20200953) Karasik D … Demissie S (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010) 3 41
- Chromogranin peptides in amyotrophic lateral sclerosis. (PMID: 18721831) Schrott-Fischer A … Marksteiner J (Regulatory peptides 2009) 3 23
- Measurements of secretogranins II, III, V and proconvertases 1/3 and 2 in plasma from patients with neuroendocrine tumours. (PMID: 18448176) Stridsberg M … Janson ET (Regulatory peptides 2008) 3 23
- Knockdown of Pdcd4 results in induction of proprotein convertase 1/3 and potent secretion of chromogranin A and secretogranin II in a neuroendocrine cell line. (PMID: 18549351) Lankat-Buttgereit B … Göke R (Biology of the cell 2008) 3 23
ExternalLinks
Products for SCG2 Gene
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- Browse Antibodies
- Browse Peptides and Proteins
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- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
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- Browse Monoclonal Antibodies
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- Invitrogen Antibodies for SCG2 (AFLGC-SCG2)
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- VectorBuilder Virus packaging for SCG2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SCG2
- antibodies-online: Show 10 available Manserin Antibodies ranked by validation data
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- Boster Bio Antibodies for SCG2
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Sources for SCG2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
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