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Aliases for SCD Gene

Aliases for SCD Gene

  • Stearoyl-CoA Desaturase 2 3 4 5
  • Fatty Acid Desaturase 2 3 4
  • Stearoyl-CoA Desaturase (Delta-9-Desaturase) 2 3
  • Stearoyl-CoA Desaturase Opposite Strand 2 3
  • Delta(9)-Desaturase 3 4
  • Acyl-CoA Desaturase 2 3
  • HSCD1 3 4
  • Predicted Protein Of HQ0998 3
  • Delta-9 Desaturase 4
  • Delta-9-Desaturase 2
  • EC 1.14.19.1 4
  • MSTP008 3
  • FADS5 3
  • SCDOS 3
  • SCD1 3

External Ids for SCD Gene

Previous HGNC Symbols for SCD Gene

  • SCDOS

Previous GeneCards Identifiers for SCD Gene

  • GC10P101000
  • GC10P101340
  • GC10P102238
  • GC10P101771
  • GC10P102096
  • GC10P095735

Summaries for SCD Gene

Entrez Gene Summary for SCD Gene

  • This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015]

GeneCards Summary for SCD Gene

SCD (Stearoyl-CoA Desaturase) is a Protein Coding gene. Diseases associated with SCD include Reye Syndrome and Fatty Liver Disease. Among its related pathways are Regulation of cholesterol biosynthesis by SREBP (SREBF) and Adipogenesis. Gene Ontology (GO) annotations related to this gene include iron ion binding and stearoyl-CoA 9-desaturase activity. An important paralog of this gene is SCD5.

UniProtKB/Swiss-Prot for SCD Gene

  • Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).

Gene Wiki entry for SCD Gene

Additional gene information for SCD Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SCD Gene

Genomics for SCD Gene

GeneHancer (GH) Regulatory Elements for SCD Gene

Promoters and enhancers for SCD Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J100345 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 650.7 +1.5 1498 6.1 MLX ARID4B SIN3A DMAP1 YY1 POLR2B FOS PAF1 SP3 SP5 PKD2L1 SCD SEC31B SLC25A28 LOC101927300 ENSG00000231188 OLMALINC
GH10J100369 Promoter/Enhancer 2.1 FANTOM5 Ensembl ENCODE dbSUPER 12.9 +25.4 25429 6.8 MLX FEZF1 DMAP1 YY1 ZNF143 ZNF548 SP3 NFYC MEF2D GLIS1 OLMALINC PHBP9 ENSG00000231188 SEC31B HIF1AN EBAG9P1 SPCS2P2 TPM4P1 SCD DNMBP
GH10J100507 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE dbSUPER 11.3 +162.6 162563 4.1 CTCF PKNOX1 NFIB MAX RAD21 RFX5 GATA3 POLR2A EGR1 ARID2 SEC31B ENSG00000231188 SCD GC10M100501 GC10M100502 ENSG00000255339
GH10J100434 Enhancer 1 ENCODE 12.2 +86.9 86944 0.2 HDGF ATF1 ARNT ARID4B SIN3A ZNF2 ZNF48 SLC30A9 ZNF213 ARID2 SEC31B SCD ENSG00000231188 WNT8B ENSG00000255339 HIF1AN NDUFB8 ENSG00000212325 OLMALINC
GH10J100433 Enhancer 0.9 Ensembl 12.2 +86.7 86686 0.2 HDGF ATF1 ARNT SIN3A ZNF48 SLC30A9 ZNF213 ZNF143 ATF7 SP3 SCD ENSG00000231188 WNT8B SEC31B ENSG00000255339 HIF1AN NDUFB8 ENSG00000212325 OLMALINC
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SCD on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SCD gene promoter:
  • PPAR-gamma1
  • PPAR-gamma2
  • NRSF form 2
  • NRSF form 1
  • COUP
  • COUP-TF
  • COUP-TF1
  • HNF-4alpha1
  • HNF-4alpha2
  • SRY

Genomic Locations for SCD Gene

Genomic Locations for SCD Gene
chr10:100,347,015-100,364,834
(GRCh38/hg38)
Size:
17,820 bases
Orientation:
Plus strand
chr10:102,106,772-102,124,591
(GRCh37/hg19)
Size:
17,820 bases
Orientation:
Plus strand

Genomic View for SCD Gene

Genes around SCD on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SCD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SCD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SCD Gene

Proteins for SCD Gene

  • Protein details for SCD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O00767-ACOD_HUMAN
    Recommended name:
    Acyl-CoA desaturase
    Protein Accession:
    O00767
    Secondary Accessions:
    • B2R5U0
    • D3DR68
    • Q16150
    • Q53GR9
    • Q5W037
    • Q5W038
    • Q6GSS4
    • Q96KF6
    • Q9BS07
    • Q9Y695

    Protein attributes for SCD Gene

    Size:
    359 amino acids
    Molecular mass:
    41523 Da
    Cofactor:
    Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
    Quaternary structure:
    • May self-associate and form homodimers.

    Three dimensional structures from OCA and Proteopedia for SCD Gene

neXtProt entry for SCD Gene

Post-translational modifications for SCD Gene

  • Ubiquitination at posLast=341341, posLast=209209, isoforms=196, and posLast=162162
  • Modification sites at PhosphoSitePlus

Other Protein References for SCD Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SCD Gene

Domains & Families for SCD Gene

Gene Families for SCD Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted membrane proteins

Protein Domains for SCD Gene

Suggested Antigen Peptide Sequences for SCD Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O00767

UniProtKB/Swiss-Prot:

ACOD_HUMAN :
  • The histidine box domains are involved in binding the catalytic metal ions.
  • Belongs to the fatty acid desaturase type 1 family.
Domain:
  • The histidine box domains are involved in binding the catalytic metal ions.
Family:
  • Belongs to the fatty acid desaturase type 1 family.
genes like me logo Genes that share domains with SCD: view

Function for SCD Gene

Molecular function for SCD Gene

UniProtKB/Swiss-Prot Function:
Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).
UniProtKB/Swiss-Prot CatalyticActivity:
Stearoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = oleoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O.
GENATLAS Biochemistry:
stearol-CoA-desaturase

Enzyme Numbers (IUBMB) for SCD Gene

Phenotypes From GWAS Catalog for SCD Gene

Gene Ontology (GO) - Molecular Function for SCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004768 stearoyl-CoA 9-desaturase activity TAS --
GO:0005506 iron ion binding IDA 18765284
GO:0016491 oxidoreductase activity IDA,IEA 15907797
GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with SCD: view
genes like me logo Genes that share phenotypes with SCD: view

Animal Models for SCD Gene

MGI Knock Outs for SCD:
  • Scd1 Scd1<tm1Ntam>

Animal Model Products

CRISPR Products

miRNA for SCD Gene

miRTarBase miRNAs that target SCD

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SCD

Clone Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SCD Gene

Localization for SCD Gene

Subcellular locations from UniProtKB/Swiss-Prot for SCD Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SCD gene
Compartment Confidence
nucleus 5
endoplasmic reticulum 5
peroxisome 3
cytosol 3
plasma membrane 2
extracellular 2
mitochondrion 2
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IDA --
GO:0005783 endoplasmic reticulum IDA,IEA --
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0016020 membrane HDA,IEA 19946888
GO:0016021 integral component of membrane IEA,IDA 18765284
genes like me logo Genes that share ontologies with SCD: view

Pathways & Interactions for SCD Gene

genes like me logo Genes that share pathways with SCD: view

SIGNOR curated interactions for SCD Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for SCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006629 lipid metabolic process IEA --
GO:0006631 fatty acid metabolic process IEA --
GO:0006633 fatty acid biosynthetic process IEA --
GO:0006636 unsaturated fatty acid biosynthetic process IDA 15907797
GO:0045540 regulation of cholesterol biosynthetic process TAS --
genes like me logo Genes that share ontologies with SCD: view

Drugs & Compounds for SCD Gene

(72) Drugs for SCD Gene - From: ClinicalTrials, ApexBio, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Fludarabine Approved Pharma DNA synthsis inhibitor 1231,1231
Oxygen Approved, Vet_approved Pharma 0
alemtuzumab Approved, Investigational Pharma Therapeutic Antibodies 319
Bosentan Approved, Investigational Pharma 106
Busulfan Approved, Investigational Pharma 569

(58) Additional Compounds for SCD Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
acetyl-coa
  • AcCoA
  • Acetyl coenzyme A
  • S-Acetyl-CoA
  • S-Acetyl-coenzyme A
  • Ac-CoA
72-89-9
stearoyl-coa
  • Octadecanoyl-CoA
  • Octadecanoyl-coenzyme A
  • S-Octadecanoate
  • S-Octadecanoate CoA
  • S-Octadecanoate coenzyme A
362-66-3
(2E)-Decenoyl-CoA
  • (e)-S-2-Decenoate
  • (e)-S-2-Decenoate CoA
  • (e)-S-2-Decenoate coenzyme A
  • (e)-S-2-Decenoic acid
  • 2-trans-Decenoyl-CoA
10018-95-8
(2E)-Dodecenoyl-CoA
1066-12-2
(2E)-Hexadecenoyl-CoA
  • (e)-C16:1 N-14-CoA
  • (e)-Hexadec-2-enoyl-CoA tetraanion
  • (e)-Hexadec-2-enoyl-coenzyme A tetraanion
  • (e)-Hexadec-2-enoyl-coenzyme A(4-)
  • trans-2-Hexadecenoyl-CoA(4-)
4460-95-1
genes like me logo Genes that share compounds with SCD: view

Transcripts for SCD Gene

mRNA/cDNA for SCD Gene

(1) REFSEQ mRNAs :
(11) Additional mRNA sequences :
(1725) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SCD Gene

Stearoyl-CoA desaturase (delta-9-desaturase):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SCD

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SCD Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6
SP1: -
SP2:

Relevant External Links for SCD Gene

GeneLoc Exon Structure for
SCD
ECgene alternative splicing isoforms for
SCD

Expression for SCD Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SCD Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SCD Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x7.2), Adipose - Visceral (Omentum) (x6.0), and Adipose - Subcutaneous (x4.9).

Protein differential expression in normal tissues from HIPED for SCD Gene

This gene is overexpressed in Fetal testis (11.1), Bone (10.3), Lung (10.0), Fetal Liver (8.0), Adrenal (7.5), and Spinal cord (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SCD Gene



NURSA nuclear receptor signaling pathways regulating expression of SCD Gene:

SCD

SOURCE GeneReport for Unigene cluster for SCD Gene:

Hs.558396

mRNA Expression by UniProt/SwissProt for SCD Gene:

O00767-ACOD_HUMAN
Tissue specificity: Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung.

Evidence on tissue expression from TISSUES for SCD Gene

  • Liver(5)
  • Nervous system(5)
  • Skin(4.9)
  • Intestine(4.5)
  • Lung(4.2)
  • Pancreas(4.2)
  • Muscle(4.1)
  • Kidney(3.9)
  • Eye(3.7)
  • Blood(3.1)
  • Heart(2.7)
  • Stomach(2.7)
  • Bone(2.3)
genes like me logo Genes that share expression patterns with SCD: view

No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for SCD Gene

Orthologs for SCD Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SCD Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SCD 34 33
  • 99.44 (n)
OneToOne
dog
(Canis familiaris)
Mammalia SCD 34 33
  • 89.42 (n)
OneToOne
cow
(Bos Taurus)
Mammalia SCD 34 33
  • 86.07 (n)
OneToMany
-- 34
  • 84 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Scd1 33
  • 83.61 (n)
mouse
(Mus musculus)
Mammalia Scd2 34
  • 83 (a)
OneToMany
Scd3 34
  • 83 (a)
OneToMany
Scd1 16 34 33
  • 82.91 (n)
Scd4 34
  • 78 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SCD 34
  • 75 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SCD 34
  • 72 (a)
OneToOne
chicken
(Gallus gallus)
Aves SCD 34 33
  • 70.52 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SCD 34
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia scd 33
  • 64.69 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8660 33
zebrafish
(Danio rerio)
Actinopterygii scdb 34 33
  • 64.18 (n)
OneToMany
scd 34 33
  • 61 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta desat2 34 35 33
  • 56.69 (n)
ManyToMany
desat1 34 35
  • 47 (a)
ManyToMany
Fad2 34 35
  • 43 (a)
ManyToMany
CG9743 34 35
  • 37 (a)
ManyToMany
CG8630 34 35
  • 37 (a)
ManyToMany
CG9747 34 35
  • 32 (a)
ManyToMany
CG15531 34 35
  • 27 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea fat-7 34 35
  • 46 (a)
ManyToMany
fat-6 34 35
  • 46 (a)
ManyToMany
fat-5 34 35
  • 41 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes OLE1 36 34
  • 22 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9947 34
  • 47 (a)
ManyToMany
CSA.9813 34
  • 46 (a)
ManyToMany
-- 34
  • 43 (a)
ManyToMany
Species where no ortholog for SCD was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SCD Gene

ENSEMBL:
Gene Tree for SCD (if available)
TreeFam:
Gene Tree for SCD (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SCD: view image

Paralogs for SCD Gene

Paralogs for SCD Gene

(1) SIMAP similar genes for SCD Gene using alignment to 1 proteins:

  • ACOD_HUMAN

Pseudogenes.org Pseudogenes for SCD Gene

genes like me logo Genes that share paralogs with SCD: view

Variants for SCD Gene

Sequence variations from dbSNP and Humsavar for SCD Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000077946 -- 100,358,254(+) G/A intron_variant
rs1000139666 -- 100,358,470(+) T/C intron_variant
rs1000503829 -- 100,346,017(+) G/C upstream_transcript_variant
rs1000527886 -- 100,345,854(+) T/C upstream_transcript_variant
rs1000624603 -- 100,359,787(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for SCD Gene

Variant ID Type Subtype PubMed ID
nsv519672 CNV gain 19592680
nsv527448 CNV gain 19592680
nsv831961 CNV loss 17160897
nsv948167 CNV duplication 23825009

Variation tolerance for SCD Gene

Residual Variation Intolerance Score: 19.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.71; 57.46% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SCD Gene

Human Gene Mutation Database (HGMD)
SCD
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SCD

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SCD Gene

Disorders for SCD Gene

MalaCards: The human disease database

(4) MalaCards diseases for SCD Gene - From: HGMD, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search SCD in MalaCards View complete list of genes associated with diseases

Additional Disease Information for SCD

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with SCD: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SCD Gene

Publications for SCD Gene

  1. Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites. (PMID: 10229681) Zhang L … Prouty SM (The Biochemical journal 1999) 2 3 4 22 58
  2. Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells. (PMID: 15610069) Zhang S … Shi Y (The Biochemical journal 2005) 3 4 22 58
  3. Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates. (PMID: 15907797) Wang J … Cao G (Biochemical and biophysical research communications 2005) 3 4 22 58
  4. Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism. (PMID: 15662557) Liew CF … McCarthy MI (Diabetologia 2004) 3 22 44 58
  5. Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues. (PMID: 7909540) Li J … Gilmour RS (International journal of cancer 1994) 2 3 4 58

Products for SCD Gene

Sources for SCD Gene

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