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Aliases for SCART1 Gene

Aliases for SCART1 Gene

  • Scavenger Receptor Family Member Expressed On T Cells 1 2 3
  • Scavenger Receptor Family Member Expressed On T-Cells 1 2 5
  • Scavenger Receptor Protein Family Member 3
  • CD163c-Alpha 3

External Ids for SCART1 Gene

Previous GeneCards Identifiers for SCART1 Gene

  • GC10P135272

Summaries for SCART1 Gene

GeneCards Summary for SCART1 Gene

SCART1 (Scavenger Receptor Family Member Expressed On T Cells 1) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity. An important paralog of this gene is DMBT1.

UniProtKB/Swiss-Prot for SCART1 Gene

  • May play a role in the immune system, perhaps as a co-receptor on alphabeta and gammadelta T-cells.

Additional gene information for SCART1 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SCART1 Gene

Genomics for SCART1 Gene

GeneHancer (GH) Regulatory Elements for SCART1 Gene

Promoters and enhancers for SCART1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I133008 Enhancer 1.3 Ensembl ENCODE dbSUPER 85.8 -443.7 -443727 3.2 PKNOX1 ARNT ZNF133 NEUROD1 YBX1 GLI4 ZBTB7B ZNF207 ZNF488 SMARCB1 LOC102723337 SCART1 ENSG00000235245 TUBGCP2 LINC01168 ZNF511 MTG1 GC10P132846
GH10I133334 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 36.2 -118.2 -118167 2.9 ATF1 SIN3A GLI4 GLIS2 KLF7 KLF13 SP3 ZNF518A RFX3 GMEB1 CALY SCART1 ZNF511 PAOX ECHS1 TUBGCP2 VENTX MTG1 FUOM GC10M133326
GH10I133356 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE 25.5 -95.1 -95102 4.5 ATF1 FOXA2 MLX ZFP64 ARID4B ZNF48 YY1 TCF12 POLR2B GLIS2 FUOM GC10P133357 GC10P133359 SCART1 TUBGCP2 ENSG00000235245 PRAP1 ECHS1 PAOX PIR54449
GH10I132964 Enhancer 1 ENCODE 43.4 -488.6 -488619 0.9 HDGF PKNOX1 ARNT SIN3A YBX1 FEZF1 GLI4 ZNF2 ZBTB7B ZNF302 LINC01166 LINC01168 SCART1 ENSG00000235245 TUBGCP2 GC10P132846
GH10I133247 Enhancer 1 ENCODE dbSUPER 27.9 -204.2 -204242 5.3 HDAC1 HDGF ATF1 ARNT YBX1 NFXL1 RAD21 ZNF48 GLIS2 ZNF366 MIR202HG TUBGCP2 SCART1 ENSG00000235245 ZNF511 VENTX PAOX ECHS1 MIR202 ENSG00000273980
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SCART1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SCART1 Gene

Genomic Locations for SCART1 Gene
chr10:133,453,928-133,523,558
(GRCh38/hg38)
Size:
69,631 bases
Orientation:
Plus strand
chr10:135,267,432-135,337,062
(GRCh37/hg19)

Genomic View for SCART1 Gene

Genes around SCART1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SCART1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SCART1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SCART1 Gene

Proteins for SCART1 Gene

  • Protein details for SCART1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4G0T1-SRCRM_HUMAN
    Recommended name:
    Scavenger receptor cysteine-rich domain-containing protein SCART1
    Protein Accession:
    Q4G0T1
    Secondary Accessions:
    • C9K0L3

    Protein attributes for SCART1 Gene

    Size:
    1027 amino acids
    Molecular mass:
    108611 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SCART1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SCART1 Gene

Post-translational modifications for SCART1 Gene

No Post-translational modifications

Other Protein References for SCART1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for SCART1 Gene

Domains & Families for SCART1 Gene

Gene Families for SCART1 Gene

Protein Domains for SCART1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SCART1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SCART1 Gene

Function for SCART1 Gene

Molecular function for SCART1 Gene

UniProtKB/Swiss-Prot Function:
May play a role in the immune system, perhaps as a co-receptor on alphabeta and gammadelta T-cells.

Phenotypes From GWAS Catalog for SCART1 Gene

Gene Ontology (GO) - Molecular Function for SCART1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005044 scavenger receptor activity IEA --
genes like me logo Genes that share ontologies with SCART1: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SCART1 Gene

Localization for SCART1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SCART1 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SCART1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 22795646
GO:0005903 brush border IDA 22795646
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SCART1: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SCART1 Gene

Pathways & Interactions for SCART1 Gene

SuperPathways for SCART1 Gene

No Data Available

Interacting Proteins for SCART1 Gene

Selected Interacting proteins: Q4G0T1-SRCRM_HUMAN for SCART1 Gene via IID

Symbol External ID(s) Details
SSC4D

Gene Ontology (GO) - Biological Process for SCART1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002456 T cell mediated immunity NAS 22795646
GO:0006898 receptor-mediated endocytosis IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with SCART1: view

No data available for Pathways by source and SIGNOR curated interactions for SCART1 Gene

Drugs & Compounds for SCART1 Gene

No Compound Related Data Available

Transcripts for SCART1 Gene

mRNA/cDNA for SCART1 Gene

(1) REFSEQ mRNAs :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SCART1 Gene

No ASD Table

Relevant External Links for SCART1 Gene

GeneLoc Exon Structure for
SCART1
ECgene alternative splicing isoforms for
SCART1

Expression for SCART1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SCART1 Gene

mRNA Expression by UniProt/SwissProt for SCART1 Gene:

Q4G0T1-SRCRM_HUMAN
Tissue specificity: Mainly expressed by CD4(+) and CD8(+) T lymphocytes. Also highly expressed in small intestine and colon. Expressed (at protein level) in small intestine, stomach, gall bladder, and placental villi.
genes like me logo Genes that share expression patterns with SCART1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SCART1 Gene

Orthologs for SCART1 Gene

Evolution for SCART1 Gene

ENSEMBL:
Gene Tree for SCART1 (if available)
TreeFam:
Gene Tree for SCART1 (if available)

No data available for Orthologs for SCART1 Gene

Paralogs for SCART1 Gene

Paralogs for SCART1 Gene

genes like me logo Genes that share paralogs with SCART1: view

Variants for SCART1 Gene

Sequence variations from dbSNP and Humsavar for SCART1 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000042474 -- 133,463,850(+) G/A intron_variant
rs1000263474 -- 133,461,205(+) G/A intron_variant
rs1000441425 -- 133,456,833(+) C/A/T intron_variant
rs1000499098 -- 133,464,277(+) G/A/T intron_variant
rs1000763004 -- 133,453,666(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SCART1 Gene

Variant ID Type Subtype PubMed ID
dgv1000n100 CNV gain 25217958
dgv1001n100 CNV gain 25217958
dgv1002n100 CNV gain 25217958
dgv1003n100 CNV gain+loss 25217958
dgv1004n100 CNV loss 25217958
dgv1005n100 CNV gain 25217958
dgv1006n100 CNV gain 25217958
dgv123n27 CNV gain 19166990
dgv124n27 CNV gain 19166990
dgv125n27 CNV gain 19166990
dgv126n27 CNV gain 19166990
dgv127n27 CNV gain 19166990
dgv1486n54 CNV gain 21841781
dgv1487n54 CNV gain 21841781
dgv1488n54 CNV gain 21841781
dgv1489n54 CNV gain 21841781
dgv1492n54 CNV loss 21841781
dgv1493n54 CNV gain 21841781
dgv1494n54 CNV gain+loss 21841781
dgv172e214 CNV gain 21293372
dgv173e214 CNV gain 21293372
dgv181e199 CNV deletion 23128226
dgv304e212 CNV gain 25503493
dgv35e55 CNV gain 17911159
dgv36e55 CNV gain 17911159
dgv39n111 CNV duplication 26073780
dgv999n100 CNV gain 25217958
esv2421904 CNV duplication 20811451
esv2750853 CNV gain 17911159
esv2750875 CNV loss 17911159
esv2759793 CNV gain+loss 17122850
esv2760130 CNV gain+loss 21179565
esv2764146 CNV gain+loss 21179565
esv28562 CNV gain+loss 19812545
esv3328248 CNV duplication 20981092
esv3363361 CNV duplication 20981092
esv33719 CNV gain 17666407
esv3579239 CNV loss 25503493
esv3625046 CNV loss 21293372
esv3625049 CNV loss 21293372
esv3891902 CNV gain+loss 25118596
nsv1043323 CNV gain 25217958
nsv1050229 CNV gain 25217958
nsv1052033 CNV gain 25217958
nsv1052904 CNV gain 25217958
nsv1075425 CNV duplication 25765185
nsv428243 CNV gain 18775914
nsv436819 CNV insertion 17901297
nsv442593 CNV gain 18776908
nsv469597 CNV gain 16826518
nsv470981 CNV gain 18288195
nsv498746 CNV loss 21111241
nsv514545 CNV gain 21397061
nsv517180 CNV gain+loss 19592680
nsv528260 CNV loss 19592680
nsv552589 CNV gain 21841781
nsv552677 CNV gain 21841781
nsv7631 CNV deletion 18451855
nsv818790 CNV gain 17921354
nsv832041 CNV gain 17160897
nsv832042 CNV gain 17160897
nsv8752 CNV gain+loss 18304495
nsv952709 CNV deletion 24416366

Additional Variant Information for SCART1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SCART1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SCART1 Gene

Disorders for SCART1 Gene

Additional Disease Information for SCART1

No disorders were found for SCART1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SCART1 Gene

Publications for SCART1 Gene

  1. Characterization of a novel human scavenger receptor cysteine-rich molecule SCART1 expressed by lymphocytes. (PMID: 22795646) Holm D … Holmskov U (Immunobiology 2013) 2 3 4 58
  2. Cloning and characterization of SCART1, a novel scavenger receptor cysteine-rich type I transmembrane molecule. (PMID: 19297026) Holm D … Holmskov U (Molecular immunology 2009) 2 3 58
  3. A novel lipid-based drug carrier targeted to the non-parenchymal cells, including hepatic stellate cells, in the fibrotic livers of bile duct ligated rats. (PMID: 17493581) Adrian JE … Poelstra K (Biochimica et biophysica acta 2007) 22 58
  4. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for SCART1 Gene

Sources for SCART1 Gene

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