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The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with... See more...
Aliases for SCARF2 Gene
Aliases for SCARF2 Gene
External Ids for SCARF2 Gene
- HGNC: 19869
- NCBI Entrez Gene: 91179
- Ensembl: ENSG00000244486
- OMIM®: 613619
- UniProtKB/Swiss-Prot: Q96GP6
Previous GeneCards Identifiers for SCARF2 Gene
- GC22M017481
- GC22M019103
- GC22M020778
- GC22M004042
Summaries for SCARF2 Gene
-
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
GeneCards Summary for SCARF2 Gene
SCARF2 (Scavenger Receptor Class F Member 2) is a Protein Coding gene. Diseases associated with SCARF2 include Van Den Ende-Gupta Syndrome and Sclerocornea. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity. An important paralog of this gene is SCARF1.
UniProtKB/Swiss-Prot Summary for SCARF2 Gene
-
Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By similarity).
Additional gene information for SCARF2 Gene
- HGNC (19869)
- NCBI Entrez Gene (91179)
- Ensembl (ENSG00000244486)
- OMIM® (613619)
- UniProtKB/Swiss-Prot (Q96GP6)
- Open Targets Platform(ENSG00000244486)
- Monarch Initiative
- Search for SCARF2 at DataMed
- Search for SCARF2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SCARF2 Gene
Genomics for SCARF2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SCARF2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SCARF2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SCARF2
- Top Transcription factor binding sites by QIAGEN in the SCARF2 gene promoter:
-
- AhR
- Arnt
- GR
- GR-alpha
- GR-beta
- Nkx2-5
- p300
- POU2F1
- POU2F1a
- Sp1
Genomic Locations for SCARF2 Gene
Latest Assembly
- chr22:20,424,584-20,437,826
- (GRCh38/hg38)
- Size:
- 13,243 bases
- Orientation:
- Minus strand
Previous Assembly
- chr22:20,778,874-20,792,112
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 13,239 bases
- Orientation:
- Minus strand
- chr22:20,778,874-20,792,146
- (GRCh37/hg19 by Ensembl)
- Size:
- 13,273 bases
- Orientation:
- Minus strand
Genomic View for SCARF2 Gene
Genes around SCARF2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q11.21 by HGNC
- 22q11.21 by Entrez Gene
- 22q11.21 by Ensembl
SCARF2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SCARF2 Gene
Proteins for SCARF2 Gene
-
Protein details for SCARF2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96GP6-SREC2_HUMAN
- Recommended name:
- Scavenger receptor class F member 2
- Protein Accession:
- Q96GP6
- E5RFB8
- Q58A83
- Q8IXF3
- Q9BW74
Protein attributes for SCARF2 Gene
- Size:
- 871 amino acids
- Molecular mass:
- 92384 Da
- Quaternary structure:
-
- Homophilic and heterophilic interaction via its extracellular domain. Interacts with SCARF1. The heterophilic interaction with SCARF1, which is stronger than the homophilic interaction with itself, is suppressed by the presence of SCARF1 ligand such as Ac-LDL (By similarity).
- SequenceCaution:
-
- Sequence=AAN45861.1; Type=Frameshift; Evidence={ECO:0000305};
Protein Expression for SCARF2 Gene
Post-translational modifications for SCARF2 Gene
Other Protein References for SCARF2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for SCARF2
- Novus Biologicals Antibodies for SCARF2
- Invitrogen Antibodies for SCARF2 (AFLGC-SCARF2)
-
Biorbyt antibodies for SCARF2
-
Boster Bio Antibodies for SCARF2
-
Custom Antibody ServicesProSci Antibodies for SCARF2
Protein products for research
-
OriGene Purified Proteins for SCARF2
- Search Origene for MassSpec and Protein Over-expression Lysates for SCARF2
- Origene Custom Protein Services for SCARF2
- Novus Biologicals proteins for SCARF2
- antibodies-online: Show 6 available SCARF2 Proteins ranked by validation data
- Compare Top SCARF2 Proteins
-
Quality Products:
Assay products for research
- RayBiotech Custom Human SREC-II ELISA and Custom Rabbit SREC-II/SCARF2 ELISA
- antibodies-online: Show 4 available SCARF2 Elisa Kits ranked by validation data
- Compare Top SCARF2 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SCARF2 Gene
Domains & Families for SCARF2 Gene
Gene Families for SCARF2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted membrane proteins
Protein Domains for SCARF2 Gene
- InterPro:
- Blocks:
-
- Laminin-type EGF-like domain
- Type I EGF
- EGF, extracellular
- ProtoNet:
Suggested Antigen Peptide Sequences for SCARF2 Gene
- GenScript: Design optimal peptide antigens:
-
- Scavenger receptor class F, member 2, isoform CRA_a (Q58A83_HUMAN)
- Scavenger receptor expressed by endothelial cells 2 protein (SREC2_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SCARF2 Gene
Function for SCARF2 Gene
Molecular function for SCARF2 Gene
- UniProtKB/Swiss-Prot Function:
- Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By similarity).
Phenotypes From GWAS Catalog for SCARF2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005044 | scavenger receptor activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 17474147 |
Phenotypes for SCARF2 Gene
- MGI mutant phenotypes for SCARF2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SCARF2:
Animal Models for SCARF2 Gene
- MGI Knock Outs for SCARF2:
-
- Scarf2 Scarf2<tm1.1(KOMP)Vlcg>
Animal Models for research
-
Taconic Biosciences Mouse Models for SCARF2
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SCARF2 - Starting at $85 >
- * SCARF2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for SCARF2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SCARF2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SCARF2
miRNA for SCARF2 Gene
- miRTarBase miRNAs that target SCARF2
-
- hsa-miR-6783-3p (MIRT487100)
- hsa-miR-1343-3p (MIRT487102)
- hsa-miR-6887-5p (MIRT487103)
- hsa-miR-6795-5p (MIRT487104)
- hsa-miR-7111-5p (MIRT487105)
- hsa-miR-5698 (MIRT487106)
- hsa-miR-6870-5p (MIRT487107)
- hsa-miR-4723-5p (MIRT487108)
- hsa-miR-486-3p (MIRT487109)
- hsa-miR-939-5p (MIRT487110)
- hsa-miR-1343-5p (MIRT487111)
- hsa-miR-6742-3p (MIRT487112)
- hsa-miR-6081 (MIRT487113)
- hsa-miR-6852-5p (MIRT487114)
- hsa-miR-939-3p (MIRT487115)
- hsa-miR-6850-3p (MIRT487116)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SCARF2
- Browse OriGene Inhibitory RNA Products For SCARF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SCARF2
Clone products for research
- Applied Biological Materials (abm): Clones for SCARF2 - Starting at $45 >
- * SCARF2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for SCARF2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SCARF2
Cell Lines for research
-
Horizon Cell Lines for SCARF2
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for SCARF2 Gene
Localization for SCARF2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SCARF2 Gene
- Membrane. Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| nucleus | 2 |
| cytosol | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cytosol (1)
- Nuclear bodies (1)
- Nucleoplasm (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005925 | focal adhesion | HDA | 21423176 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for SCARF2 Gene
Interacting Proteins for SCARF2 Gene
Selected Interacting proteins:
Q96GP6-SREC2_HUMAN
ENSP00000477564
for SCARF2 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SCARF2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006897 | endocytosis | IEA | -- |
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for SCARF2 Gene
Transcripts for SCARF2 Gene
mRNA/cDNA for SCARF2 Gene
- 2 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000494535 780 nts (view in UCSC)
- ENST00000622235 3463 nts (view in UCSC)
- ENST00000623402 3248 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SCARF2 - Starting at $85 >
- * SCARF2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for SCARF2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SCARF2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SCARF2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SCARF2
- Browse OriGene Inhibitory RNA Products For SCARF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SCARF2
Clone products for research
- Applied Biological Materials (abm): Clones for SCARF2 - Starting at $45 >
- * SCARF2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for SCARF2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SCARF2
Relevant External Links for SCARF2 Gene
- GeneLoc Exon Structure for
- SCARF2
Expression for SCARF2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Head Mesenchyme (Muscoskeletal System)
- Dental Mesenchymal Cells Branchial Arch 1
-
Tooth
- Dental Mesenchymal Cells Branchial Arch 1
mRNA differential expression in normal tissues according to GTEx for SCARF2 Gene
This gene is overexpressed in Artery - Aorta (x4.3).
This gene is overexpressed in Heart (35.6), Platelet (14.1), and Monocytes (8.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SCARF2 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SCARF2
SOURCE GeneReport for Unigene cluster for SCARF2 Gene:
Hs.474251mRNA Expression by UniProt/SwissProt for SCARF2 Gene:
Q96GP6-SREC2_HUMAN
Tissue specificity:
Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary.
Evidence on tissue expression from TISSUES for SCARF2 Gene
- Nervous system(4.3)
- Liver(4.3)
Phenotype-based relationships between genes and organs from Gene ORGANizer for SCARF2 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- integumentary
- nervous
- reproductive
- respiratory
- skeleton
Regions:
Head and neck:
- cheek
- ear
- epiglottis
- eye
- eyelid
- face
- forehead
- head
- jaw
- larynx
- lip
- mandible
- maxilla
- mouth
- neck
- nose
- outer ear
- pharynx
- skull
- tooth
- vocal cord
Thorax:
- bronchus
- chest wall
- clavicle
- rib
- rib cage
- scapula
- sternum
- trachea
Pelvis:
- pelvis
- uterus
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- blood
- blood vessel
- hair
- skin
- spinal column
- vertebrae
Primer products for research
-
OriGene qPCR primer pairs for SCARF2
Gene Expression Assays for research
Orthologs for SCARF2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SCARF2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SCARF2 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Scarf2 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | SCARF2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Scarf2 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SCARF2 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
| Chicken (Gallus gallus) |
Aves | SCARF2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SCARF2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100485666 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | LOC100329632 30 |
|
||
| SCARF2 31 |
|
OneToOne | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | nimA 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for SCARF2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SCARF2 Gene
- ENSEMBL:
- Gene Tree for SCARF2 (if available)
- TreeFam:
- Gene Tree for SCARF2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SCARF2: view image
Paralogs for SCARF2 Gene
Variants for SCARF2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SCARF2 Gene
| SNP ID | Clinical significance and condition | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 813638 | Uncertain Significance: Microcephaly | 20,425,946(-) |
G/A NM_182895.5(SCARF2):c.2030C>T (p.Ala677Val) |
MISSENSE | |
| 993021 | Likely Pathogenic: Van den Ende-Gupta syndrome | 20,437,729(-) |
GC/G NM_182895.5(SCARF2):c.25del (p.Ala9fs) |
FRAMESHIFT | |
| rs1241075295 | Likely Pathogenic: Van den Ende-Gupta syndrome | 20,430,848(-) |
G/C NM_182895.5(SCARF2):c.915C>G (p.Cys305Trp) |
MISSENSE | |
| rs1475035263 | Uncertain Significance: not provided | 20,426,096(-) |
G/A NM_182895.5(SCARF2):c.1880C>T (p.Ala627Val) |
MISSENSE | |
| rs367657189 | Uncertain Significance: not provided | 20,425,397(-) |
C/T NM_153334.7(SCARF2):c.2594G>A (p.Arg865Lys) |
MISSENSE |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4483n100 | CNV | gain | 25217958 |
| dgv7993n54 | CNV | gain | 21841781 |
| esv3575430 | CNV | gain | 25503493 |
| esv3647292 | CNV | gain | 21293372 |
| esv3647293 | CNV | gain | 21293372 |
| esv3893438 | CNV | gain | 25118596 |
| nsv1056614 | CNV | loss | 25217958 |
| nsv436864 | CNV | insertion | 17901297 |
| nsv509809 | CNV | insertion | 20534489 |
| nsv519901 | CNV | gain | 19592680 |
| nsv523162 | CNV | loss | 19592680 |
| nsv588293 | CNV | gain | 21841781 |
| nsv828954 | CNV | gain | 20364138 |
| nsv828955 | CNV | gain | 20364138 |
| nsv834135 | CNV | gain | 17160897 |
| nsv834136 | CNV | loss | 17160897 |
| nsv834138 | CNV | loss | 17160897 |
| nsv953032 | CNV | deletion | 24416366 |
Gene Damage Index Score:
12.49;
94.36% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SCARF2 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SCARF2 Gene
Disorders for SCARF2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| van den ende-gupta syndrome |
|
|
| sclerocornea |
|
|
| blepharophimosis |
|
|
| cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome |
|
|
| eyelid disease |
|
|
Search SCARF2 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
SREC2_HUMAN- Van den Ende-Gupta syndrome (VDEGS) [MIM:600920]: A syndrome characterized by craniofacial and skeletal abnormalities that include blepharophimosis, a flat and wide nasal bridge, narrow and beaked nose, hypoplastic maxilla with or without cleft palate and everted lower lip, prominent ears, down-slanting eyes, arachnodactyly, and camptodactyly. Patients present congenital joint contractures that improve without intervention, and normal growth and development. Intelligence is normal. Rarely, enlarged cerebella can be present. Some patients experience respiratory problems due to laryngeal abnormalities. {ECO:0000269 PubMed:20887961}. Note=The disease is caused by variants affecting the gene represented in this entry.
Additional Disease Information for SCARF2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for Genatlas for SCARF2 Gene
Publications for SCARF2 Gene
- Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome. (PMID: 20887961) Anastasio N … Jerome-Majewska LA (American journal of human genetics 2010) 3 4 74
- SREC-II, a new member of the scavenger receptor type F family, trans-interacts with SREC-I through its extracellular domain. (PMID: 12154095) Ishii J … Arai H (The Journal of biological chemistry 2002) 2 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane. (PMID: 32788342) Hannigan MM … Nicchitta CV (Molecular & cellular proteomics : MCP 2020) 3
- LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. (PMID: 31073040) Choi JH … Beutler B (Science (New York, N.Y.) 2019) 3
ExternalLinks
Products for SCARF2 Gene
- View all 4 R&D Systems SCARF2 (SREC-II/SCARF2) Products
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- Taconic Biosciences Mouse Models for SCARF2
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- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for SCARF2 (AFLGC-SCARF2)
- VectorBuilder Custom and pre-made DNA vectors for SCARF2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SCARF2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SCARF2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SCARF2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SCARF2
- antibodies-online: Show 11 available SCARF2 Antibodies ranked by validation data
- Compare Top SCARF2 Antibodies
- antibodies-online: Show 4 available SCARF2 Elisa Kits ranked by validation data
- Compare Top SCARF2 Elisa Kits
- Quality Products:
- antibodies-online: Show 6 available SCARF2 Proteins ranked by validation data
- Compare Top SCARF2 Proteins
- Quality Products:
- Custom Antibody ServicesProSci Antibodies for SCARF2
- Search for SCARF2 Proteins at ProSci
- Horizon Cell Lines for SCARF2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SCARF2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SCARF2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SCARF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SCARF2
- Boster Bio Antibodies for SCARF2
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for SCARF2
Sources for SCARF2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB