Aliases for SCAI Gene
External Ids for SCAI Gene
Previous HGNC Symbols for SCAI Gene
Previous GeneCards Identifiers for SCAI Gene
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
GeneCards Summary for SCAI Gene
SCAI (Suppressor Of Cancer Cell Invasion) is a Protein Coding gene. Diseases associated with SCAI include Vertebral Artery Insufficiency. Among its related pathways are Signaling by Rho GTPases and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include transcription corepressor activity.
UniProtKB/Swiss-Prot for SCAI Gene
Tumor suppressor which functions to suppress MKL1-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1.