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SBNO1 (Strawberry Notch Homolog 1) is a Protein Coding gene. Diseases associated with SBNO1 include Congenital Muscular Dystrophy-Dystroglycanopathy Type A6. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and hydrolase activity. An important paralog of this gene is SBNO2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003674 | molecular_function | ND | -- |
GO:0031490 | chromatin DNA binding | IBA | 21873635 |
GO:0042393 | histone binding | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005575 | cellular_component | ND | -- |
GO:0005634 | nucleus | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006355 | regulation of transcription, DNA-templated | IBA | 21873635 |
GO:0008150 | biological_process | ND | -- |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP7: | - |
ExUns: | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||||||||
SP2: | |||||||||||||||||
SP3: | - | ||||||||||||||||
SP4: | |||||||||||||||||
SP5: | |||||||||||||||||
SP6: | |||||||||||||||||
SP7: |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | SBNO1 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
Dog (Canis familiaris) |
Mammalia | SBNO1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | SBNO1 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Sbno1 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Sbno1 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | SBNO1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | SBNO1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | SBNO1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | sbno1 30 |
|
||
Str.16725 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.19331 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | sbno1 30 |
|
||
SBNO1 31 |
|
OneToOne | |||
Dr.25585 30 |
|
||||
Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.13697 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | sno 30 31 |
|
ManyToMany | |
CG3491 31 |
|
ManyToMany | |||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP011199 30 |
|
||
Worm (Caenorhabditis elegans) |
Secernentea | let-765 30 31 |
|
OneToMany | |
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | EMB1135 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os08g0223700 30 |
|
||
Os.14486 30 |
|
||||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.5085 31 |
|
OneToMany | |
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.5929 30 |
|
SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1060105 | -. - |
p.Ser728Asnp.Ser729Asn |
|||
rs114314586 | Likely Benign: not provided | 123,321,537(-) |
T/C NM_001167856.3(SBNO1):c.2321A>G (p.Asn774Ser) |
MISSENSE | |
rs115621242 | Benign: not provided | 123,298,083(-) |
G/A NM_001167856.3(SBNO1):c.3934C>T (p.Leu1312=) |
SYNONYMOUS | |
rs116725625 | Benign: not provided | 123,341,088(-) |
G/A NM_001167856.3(SBNO1):c.551C>T (p.Thr184Ile) |
MISSENSE | |
rs118119987 | Benign: not provided | 123,341,093(-) |
G/A NM_001167856.3(SBNO1):c.551-5C>T |
INTRON |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2746502 | CNV | deletion | 23290073 |
esv2746503 | CNV | deletion | 23290073 |
esv2746504 | CNV | deletion | 23290073 |
esv3549920 | CNV | deletion | 23714750 |
nsv1127301 | CNV | deletion | 24896259 |
nsv1144662 | CNV | deletion | 24896259 |
nsv477316 | CNV | novel sequence insertion | 20440878 |
Disorder | Aliases | PubMed IDs |
---|---|---|
congenital muscular dystrophy-dystroglycanopathy type a6 |
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