Aliases for SARM1 Gene

Aliases for SARM1 Gene

  • Sterile Alpha And TIR Motif Containing 1 2 3 5
  • SAMD2 2 3 4
  • SARM 2 3 4
  • Sterile Alpha And TIR Motif-Containing Protein 1 3 4
  • Sterile Alpha Motif Domain-Containing Protein 2 3 4
  • Sterile Alpha And Armadillo Repeat Protein 3 4
  • SAM Domain-Containing Protein 2 3 4
  • NADP(+) Hydrolase SARM1 3 4
  • NAD(+) Hydrolase SARM1 3 4
  • Tir-1 Homolog 3 4
  • NADase SARM1 3 4
  • KIAA0524 2 4
  • MyD88-5 3 4
  • HSARM1 3 4
  • HsTIR 3 4
  • Sterile Alpha And HEAT/Armadillo Motif Protein, Ortholog Of Drosophila 3
  • EC 3.2.2.6 4
  • EC 3.2.2.- 4
  • SARM1 5

External Ids for SARM1 Gene

Previous GeneCards Identifiers for SARM1 Gene

  • GC17P026550
  • GC17P026844
  • GC17P023723
  • GC17P026685
  • GC17P026698
  • GC17P022907

Summaries for SARM1 Gene

GeneCards Summary for SARM1 Gene

SARM1 (Sterile Alpha And TIR Motif Containing 1) is a Protein Coding gene. Diseases associated with SARM1 include Wallerian Degeneration and Bullous Retinoschisis. Among its related pathways are Activated TLR4 signalling and IKK complex recruitment mediated by RIP1. Gene Ontology (GO) annotations related to this gene include binding.

UniProtKB/Swiss-Prot Summary for SARM1 Gene

  • NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (PubMed:25908823, PubMed:27671644, PubMed:28334607). Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (PubMed:15123841, PubMed:16964262, PubMed:20306472, PubMed:25908823). Wallerian degeneration is triggered by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADPR (cADPR) and nicotinamide; NAD(+) cleavage promoting cytoskeletal degradation and axon destruction (PubMed:25908823, PubMed:28334607, PubMed:30333228, PubMed:31128467, PubMed:31439793, PubMed:31439792). Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (PubMed:29395922). Can activate neuronal cell death in response to stress (PubMed:20306472). Regulates dendritic arborization through the MAPK4-JNK pathway (By similarity). Involved in innate immune response: inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38 (PubMed:16964262).

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SARM1 Gene

Genomics for SARM1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SARM1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SARM1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SARM1

Top Transcription factor binding sites by QIAGEN in the SARM1 gene promoter:
  • AhR
  • ARP-1
  • ATF
  • GATA-2
  • LyF-1
  • NF-kappaB
  • NF-kappaB1
  • NRSF form 1
  • NRSF form 2
  • p300

Genomic Locations for SARM1 Gene

Genomic Locations for SARM1 Gene
chr17:28,364,356-28,404,049
(GRCh38/hg38)
Size:
39,694 bases
Orientation:
Plus strand
chr17:26,691,378-26,728,065
(GRCh37/hg19)
Size:
36,688 bases
Orientation:
Plus strand

Genomic View for SARM1 Gene

Genes around SARM1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SARM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SARM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SARM1 Gene

Proteins for SARM1 Gene

  • Protein details for SARM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6SZW1-SARM1_HUMAN
    Recommended name:
    NAD(+) hydrolase SARM1
    Protein Accession:
    Q6SZW1
    Secondary Accessions:
    • O60277
    • Q7LGG3
    • Q9NXY5

    Protein attributes for SARM1 Gene

    Size:
    724 amino acids
    Molecular mass:
    79388 Da
    Quaternary structure:
    • Homooctamer; forms an octomeric ring via SAM domains (PubMed:31278906, PubMed:31439792). Interacts with TICAM1/TRIF and thereby interferes with TICAM1/TRIF function (PubMed:16964262). Interacts with MAPK10/JNK3 and SDC2 (via cytoplasmic domain) (By similarity).

    Three dimensional structures from OCA and Proteopedia for SARM1 Gene

    Alternative splice isoforms for SARM1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SARM1 Gene

Post-translational modifications for SARM1 Gene

  • Phosphorylation at Ser-548 by JNK kinases (MAPK8, MAPK9 and /or MAPK10) enhance the NAD(+) hydrolase (NADase) activity (PubMed:30333228). Phosphorylation at Ser-548 and subsequent activation takes place in response to oxidative stress conditions and inhibits mitochondrial respiration (PubMed:30333228).
  • Ubiquitination at Lys363
  • Modification sites at PhosphoSitePlus

Other Protein References for SARM1 Gene

No data available for DME Specific Peptides for SARM1 Gene

Domains & Families for SARM1 Gene

Protein Domains for SARM1 Gene

InterPro:
Blocks:
  • Sterile alpha motif SAM
  • Sterile alpha motif homology 2
ProtoNet:

Suggested Antigen Peptide Sequences for SARM1 Gene

GenScript: Design optimal peptide antigens:
  • SARM1 protein (Q05B42_HUMAN)
  • SARM1 protein (Q0D2N8_HUMAN)
  • Tir-1 homolog (SARM1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6SZW1

UniProtKB/Swiss-Prot:

SARM1_HUMAN :
  • The TIR domain mediates NAD(+) hydrolase (NADase) activity (PubMed:28334607). Self-association of TIR domains is required for NADase activity (PubMed:27671644, PubMed:31278906).
  • Belongs to the SARM1 family.
Domain:
  • The TIR domain mediates NAD(+) hydrolase (NADase) activity (PubMed:28334607). Self-association of TIR domains is required for NADase activity (PubMed:27671644, PubMed:31278906).
Family:
  • Belongs to the SARM1 family.
genes like me logo Genes that share domains with SARM1: view

Function for SARM1 Gene

Molecular function for SARM1 Gene

UniProtKB/Swiss-Prot Function:
NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (PubMed:25908823, PubMed:27671644, PubMed:28334607). Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (PubMed:15123841, PubMed:16964262, PubMed:20306472, PubMed:25908823). Wallerian degeneration is triggered by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADPR (cADPR) and nicotinamide; NAD(+) cleavage promoting cytoskeletal degradation and axon destruction (PubMed:25908823, PubMed:28334607, PubMed:30333228, PubMed:31128467, PubMed:31439793, PubMed:31439792). Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (PubMed:29395922). Can activate neuronal cell death in response to stress (PubMed:20306472). Regulates dendritic arborization through the MAPK4-JNK pathway (By similarity). Involved in innate immune response: inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38 (PubMed:16964262).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide; Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6; Evidence={ECO:0000269|PubMed:28334607, ECO:0000269|PubMed:30333228, ECO:0000269|PubMed:31128467, ECO:0000269|PubMed:31439792, ECO:0000269|PubMed:31439793};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=NAD(+) = cyclic ADP-ribose + H(+) + nicotinamide; Xref=Rhea:RHEA:38611, ChEBI:CHEBI:15378, ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:73672; Evidence={ECO:0000269|PubMed:28334607, ECO:0000269|PubMed:31128467};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=H2O + NADP(+) = ADP-D-ribose 2'-phosphate + H(+) + nicotinamide; Xref=Rhea:RHEA:19849, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17154, ChEBI:CHEBI:58349, ChEBI:CHEBI:58673; Evidence={ECO:0000269|PubMed:29395922};.
UniProtKB/Swiss-Prot Induction:
Up-regulated by lipopolysaccharides (LPS).
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=24 uM for NAD(+) {ECO:0000269|PubMed:28334607}; Note=kcat is 10.3 min(-1) with NAD(+) as substrate. {ECO:0000269|PubMed:28334607};
UniProtKB/Swiss-Prot EnzymeRegulation:
Autoinhibited: in the inactive state, the enzymatic TIR domain is held apart by the autoinhibiting ARM domain (PubMed:27671644, PubMed:31278906). Following activation, possibly by nicotinamide mononucleotide (NMN), auto-inhibitory interactions are released, allowing self-association of the TIR domains and subsequent activation of the NAD(+) hydrolase (NADase) activity (PubMed:27671644, PubMed:31128467). Self-association of TIR domains is facilitated by the octamer of SAM domains (PubMed:31278906, PubMed:31439792). NAD(+) hydrolase activity is inhibited by nicotinamide (PubMed:28334607).

Enzyme Numbers (IUBMB) for SARM1 Gene

Phenotypes From GWAS Catalog for SARM1 Gene

Gene Ontology (GO) - Molecular Function for SARM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003953 NAD+ nucleosidase activity IDA 28334607
GO:0005515 protein binding IEA,IPI 17258210
GO:0016787 hydrolase activity IEA --
GO:0035591 signaling adaptor activity IEA --
GO:0050135 NAD(P)+ nucleosidase activity IEA --
genes like me logo Genes that share ontologies with SARM1: view
genes like me logo Genes that share phenotypes with SARM1: view

Animal Models for SARM1 Gene

MGI Knock Outs for SARM1:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SARM1

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SARM1 Gene

Localization for SARM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SARM1 Gene

Cytoplasm. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse. Mitochondrion. Note=Associated with microtubules. {ECO:0000250 UniProtKB:Q6PDS3}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SARM1 gene
Compartment Confidence
mitochondrion 5
cytosol 5
cytoskeleton 4
plasma membrane 2
extracellular 2
nucleus 2
endosome 2
peroxisome 1
endoplasmic reticulum 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for SARM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm ISS --
GO:0005739 mitochondrion IEA,IDA 22145856
GO:0005829 cytosol TAS --
GO:0005874 microtubule IEA,ISS --
GO:0015630 microtubule cytoskeleton IEA --
genes like me logo Genes that share ontologies with SARM1: view

Pathways & Interactions for SARM1 Gene

genes like me logo Genes that share pathways with SARM1: view

Pathways by source for SARM1 Gene

SIGNOR curated interactions for SARM1 Gene

Inactivates:

Gene Ontology (GO) - Biological Process for SARM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002376 immune system process IEA --
GO:0007165 signal transduction IEA --
GO:0007399 nervous system development IEA --
GO:0009749 response to glucose IEA --
GO:0009967 positive regulation of signal transduction IEA --
genes like me logo Genes that share ontologies with SARM1: view

Drugs & Compounds for SARM1 Gene

No Compound Related Data Available

Transcripts for SARM1 Gene

mRNA/cDNA for SARM1 Gene

1 REFSEQ mRNAs :
10 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SARM1

Alternative Splicing Database (ASD) splice patterns (SP) for SARM1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d ^ 11a · 11b · 11c ^ 12a · 12b · 12c
SP1: - - - - - -
SP2: - - - - - -
SP3: - - - -
SP4: - - - - -
SP5: - - - -
SP6: - -
SP7:
SP8:

Relevant External Links for SARM1 Gene

GeneLoc Exon Structure for
SARM1

Expression for SARM1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SARM1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SARM1 Gene

This gene is overexpressed in Testis (14.5), Fetal Brain (12.8), and Retina (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SARM1 Gene



Protein tissue co-expression partners for SARM1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SARM1

SOURCE GeneReport for Unigene cluster for SARM1 Gene:

Hs.743510

mRNA Expression by UniProt/SwissProt for SARM1 Gene:

Q6SZW1-SARM1_HUMAN
Tissue specificity: Predominantly expressed in brain, kidney and liver. Expressed at lower level in placenta.

Evidence on tissue expression from TISSUES for SARM1 Gene

  • Nervous system(4.7)
  • Eye(2.5)
  • Blood(2.4)
  • Muscle(2)
genes like me logo Genes that share expression patterns with SARM1: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SARM1 Gene

Orthologs for SARM1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SARM1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SARM1 30 31
  • 99.95 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia SARM1 30 31
  • 92.22 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Sarm1 30 17 31
  • 88.18 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Sarm1 30
  • 88.13 (n)
Cow
(Bos Taurus)
Mammalia SARM1 31
  • 82 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia SARM1 31
  • 78 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia SARM1 31
  • 45 (a)
OneToOne
Chicken
(Gallus gallus)
Aves SARM1 30 31
  • 72.35 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia SARM1 31
  • 66 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia sarm1 30
  • 63.83 (n)
Zebrafish
(Danio rerio)
Actinopterygii sarm1 30 31
  • 64.53 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005901 30
  • 56.8 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta Ect4 30 31
  • 54.99 (n)
OneToOne
Worm
(Caenorhabditis elegans)
Secernentea tir-1 30 31
  • 47.1 (n)
OneToOne
Species where no ortholog for SARM1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for SARM1 Gene

ENSEMBL:
Gene Tree for SARM1 (if available)
TreeFam:
Gene Tree for SARM1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SARM1: view image

Paralogs for SARM1 Gene

No data available for Paralogs for SARM1 Gene

Variants for SARM1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SARM1 Gene

SNP ID Clinical significance and condition Chr 17 pos Variation AA Info Type
888567 Benign: Congenital defect of folate absorption 28,395,072(+) G/A THREE_PRIME_UTR_VARIANT,INTRON_VARIANT
888568 Uncertain Significance: Congenital defect of folate absorption 28,395,238(+) G/A THREE_PRIME_UTR_VARIANT,INTRON_VARIANT
888569 Uncertain Significance: Congenital defect of folate absorption 28,395,472(+) A/C THREE_PRIME_UTR_VARIANT,INTRON_VARIANT
888617 Likely Benign: Congenital defect of folate absorption 28,396,536(+) T/C THREE_PRIME_UTR_VARIANT
888618 Uncertain Significance: Congenital defect of folate absorption 28,396,711(+) C/T THREE_PRIME_UTR_VARIANT

Additional dbSNP identifiers (rs#s) for SARM1 Gene

Structural Variations from Database of Genomic Variants (DGV) for SARM1 Gene

Variant ID Type Subtype PubMed ID
esv2715786 CNV deletion 23290073
esv2715788 CNV deletion 23290073
esv2715789 CNV deletion 23290073
nsv1056839 CNV gain 25217958
nsv1062056 CNV gain 25217958
nsv1125214 CNV deletion 24896259
nsv519388 CNV loss 19592680
nsv574653 CNV gain 21841781

Variation tolerance for SARM1 Gene

Gene Damage Index Score: 1.99; 36.72% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SARM1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SARM1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SARM1 Gene

Disorders for SARM1 Gene

MalaCards: The human disease database

(3) MalaCards diseases for SARM1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
wallerian degeneration
  • wallerian degeneration of the pyramidal tract
bullous retinoschisis
retinoschisis 1, x-linked, juvenile
  • rs1
- elite association - COSMIC cancer census association via MalaCards
Search SARM1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for SARM1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with SARM1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SARM1 Gene

Publications for SARM1 Gene

  1. Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. (PMID: 15123841) Liberati NT … Ausubel FM (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 23
  2. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 2 3 4
  3. Structural Evidence for an Octameric Ring Arrangement of SARM1. (PMID: 31278906) Sporny M … Opatowsky Y (Journal of molecular biology 2019) 3 4
  4. NAD+ cleavage activity by animal and plant TIR domains in cell death pathways. (PMID: 31439792) Horsefield S … Kobe B (Science (New York, N.Y.) 2019) 3 4
  5. TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death. (PMID: 31439793) Wan L … Nishimura MT (Science (New York, N.Y.) 2019) 3 4

Products for SARM1 Gene

Sources for SARM1 Gene