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SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008] See more...
Aliases for SAP130 Gene
Aliases for SAP130 Gene
External Ids for SAP130 Gene
- HGNC: 29813
- Entrez Gene: 79595
- Ensembl: ENSG00000136715
- OMIM: 609697
- UniProtKB: Q9H0E3
Previous GeneCards Identifiers for SAP130 Gene
- GC02M128603
- GC02M128792
- GC02M128415
- GC02M121004
- GC02M127942
- GC02M127945
- GC02M127967
Summaries for SAP130 Gene
-
SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SAP130 Gene
SAP130 (Sin3A Associated Protein 130) is a Protein Coding gene. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include transcription coactivator activity and histone acetyltransferase activity.
UniProtKB/Swiss-Prot Summary for SAP130 Gene
-
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Additional gene information for SAP130 Gene
- HGNC(29813)
- Entrez Gene(79595)
- Ensembl(ENSG00000136715)
- OMIM(609697)
- UniProtKB(Q9H0E3)
- Open Targets Platform(ENSG00000136715)
- Search for SAP130 at DataMed
- Search for SAP130 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SAP130 Gene
Genomics for SAP130 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SAP130 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SAP130 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SAP130
- Top Transcription factor binding sites by QIAGEN in the SAP130 gene promoter:
-
- AP-2alpha
- AP-2alphaA
- AP-2beta
- AP-2gamma
- Nkx3-1
- Nkx3-1 v1
- Nkx3-1 v2
- Nkx3-1 v3
- USF-1
- USF1
Genomic Locations for SAP130 Gene
Genomic Locations for SAP130 Gene
- chr2:127,941,217-128,028,120
- (GRCh38/hg38)
- Size:
- 86,904 bases
- Orientation:
- Minus strand
- chr2:128,698,791-128,785,694
- (GRCh37/hg19)
- Size:
- 86,904 bases
- Orientation:
- Minus strand
Genomic View for SAP130 Gene
Genes around SAP130 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q14.3 by HGNC
- 2q14.3 by Entrez Gene
- 2q14.3 by Ensembl
SAP130 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SAP130 Gene
Proteins for SAP130 Gene
-
Protein details for SAP130 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H0E3-SP130_HUMAN
- Recommended name:
- Histone deacetylase complex subunit SAP130
- Protein Accession:
- Q9H0E3
- B7ZLM3
- C9K0X9
- Q4ZFV4
- Q53T46
- Q8WVW4
- Q9H9G8
Protein attributes for SAP130 Gene
- Size:
- 1048 amino acids
- Molecular mass:
- 110324 Da
- Quaternary structure:
-
- Component of a mSin3A corepressor complex that contains SIN3A, SAP130, SUDS3/SAP45, ARID4B/SAP180, HDAC1 and HDAC2. Interacts (released by dead or dying cells) with CLEC4E (By similarity).
Protein Expression for SAP130 Gene
Post-translational modifications for SAP130 Gene
- Acetylated.
- Sumoylated with SUMO1.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for SAP130 Gene
Antibody Products
- G Biosciences Immunotag™ SAP130 Antibody
-
Custom Antibody ServicesOriGene Antibodies for SAP130
- Novus Biologicals Antibodies for SAP130
-
Abcam antibodies for SAP130
- Invitrogen Antibodies for SAP130 (AFLGC-Sap130)
-
Boster Bio Antibodies for SAP130
Protein Products
-
OriGene Purified Proteins for SAP130
- Search Origene for MassSpec and Protein Over-expression Lysates for SAP130
- Origene Custom Protein Services for SAP130
- antibodies-online: Show 3 available SAP130 Proteins ranked by validation data
- Compare Top SAP130 Proteins
-
Quality Products:
-
Signalway Proteins for SAP130
-
Abcam proteins for SAP130
Assay Products
- G Biosciences Immunotag™ Human AP13 (Apelin 13) ELISA
- antibodies-online: Show 1 available SAP130 Elisa Kits ranked by validation data
- Compare Top SAP130 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SAP130 Gene
Domains & Families for SAP130 Gene
Gene Families for SAP130 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SAP130 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SAP130 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ31417 fis, clone NT2NE2000327, weakly similar to GLUCOAMYLASE S1/S2 (EC 3.2.1.3) (Q96DP1_HUMAN)
- Sin3-associated polypeptide p130 (SP130_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9H0E3UniProtKB/Swiss-Prot:
SP130_HUMAN :- The N-terminus may interact with a transcriptional coactivator.
- Belongs to the SAP130 family.
- Domain:
-
- The N-terminus may interact with a transcriptional coactivator.
- The C-terminus may interact with HDAC-dependent and HDAC-independent corepressors.
- Family:
-
- Belongs to the SAP130 family.
Function for SAP130 Gene
Molecular function for SAP130 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Phenotypes From GWAS Catalog for SAP130 Gene
Phenotypes for SAP130 Gene
- MGI mutant phenotypes for SAP130:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for SAP130:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased vaccinia virus (VACV) infection
- Decreased viability
- Decreased viability of wild-type and TP53 knockout cells
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Increased JFH-1 genotype 2a Hepatitis C virus (HCV) infection
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- FOXO1 nuclear localization
- Increased Nanog expression
- Increased transcriptional activity
- Decreased homologous recombination repair frequency
- Decreased Dengue Infection
- Decreased infection with West Nile virus (WNV)
- Decreased West Nile virus (WNV) infection
- Increased caspase activity
Animal Models for SAP130 Gene
- MGI Knock Outs for SAP130:
-
- Sap130 Sap130<tm1a(KOMP)Mbp>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SAP130 - Select products 50% OFF >
- * SAP130 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SAP130
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SAP130
-
Santa Cruz Biotechnology (SCBT) CRISPR for SAP130
miRNA for SAP130 Gene
- miRTarBase miRNAs that target SAP130
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SAP130
- Browse OriGene Inhibitory RNA Products For SAP130
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SAP130
Clone Products
- Applied Biological Materials (abm): Clones for SAP130 - Select products 50% OFF >
- * SAP130 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SAP130
- Addgene plasmids for SAP130
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SAP130
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SAP130 Gene
Localization for SAP130 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SAP130 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| cytosol | 1 |
- Nuclear speckles (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0016607 | nuclear speck | IDA | -- |
| GO:0070822 | Sin3-type complex | IBA | 21873635 |
Pathways & Interactions for SAP130 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Chromatin organization | ||
| 2 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | ||
| 3 | Gene Expression |
.48
|
|
| 4 | RNA Polymerase II Transcription Initiation And Promoter Clearance |
Transcription Ligand-Dependent Transcription of Retinoid-Target genes
.33
|
|
| 5 | Development NOTCH1-mediated pathway for NF-KB activity modulation |
Transcription Sin3 and NuRD in transcription regulation
.31
|
|
Pathways by source for SAP130 Gene
7 Reactome pathways for SAP130 Gene
2 GeneGo (Thomson Reuters) pathways for SAP130 Gene
- Transcription Ligand-Dependent Transcription of Retinoid-Target genes
- Transcription Sin3 and NuRD in transcription regulation
Interacting Proteins for SAP130 Gene
Selected Interacting proteins:
Q9H0E3-SP130_HUMAN
ENSP00000350333
for SAP130 Gene via
MINT
STRING
IID
GPS-Prot Interaction Network for SAP130
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IMP | 22783022 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
No data available for SIGNOR curated interactions for SAP130 Gene
Transcripts for SAP130 Gene
mRNA/cDNA for SAP130 Gene
- 7 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000259234 4140 nts (view in UCSC)
- ENST00000259235 4065 nts (view in UCSC)
- ENST00000357702 4173 nts (view in UCSC)
- ENST00000424298 849 nts (view in UCSC)
- ENST00000450957 559 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SAP130 - Select products 50% OFF >
- * SAP130 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SAP130
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SAP130
-
Santa Cruz Biotechnology (SCBT) CRISPR for SAP130
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SAP130
- Browse OriGene Inhibitory RNA Products For SAP130
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SAP130
Clone Products
- Applied Biological Materials (abm): Clones for SAP130 - Select products 50% OFF >
- * SAP130 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SAP130
- Addgene plasmids for SAP130
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SAP130
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16a | · | 16b | · | 16c | · | 16d | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: |
| ExUns: | 20a | · | 20b | · | 20c | · | 20d | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23 | ^ | 24 | ^ | 25a | · | 25b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||
| SP11: |
Relevant External Links for SAP130 Gene
- GeneLoc Exon Structure for
- SAP130
Expression for SAP130 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- XY Germ Cells Testis Cord
-
Gonad
- XY Germ Cells Testis Cord
This gene is overexpressed in CD8 Tcells (15.9) and Lymph node (9.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SAP130 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SAP130
SOURCE GeneReport for Unigene cluster for SAP130 Gene:
Hs.32995mRNA Expression by UniProt/SwissProt for SAP130 Gene:
Q9H0E3-SP130_HUMAN
Tissue specificity:
Expressed in various cancer cell ines.
Evidence on tissue expression from TISSUES for SAP130 Gene
- Liver(4.2)
- Nervous system(3.1)
Primer Products
-
OriGene qPCR primer pairs for SAP130
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SAP130 Gene
Orthologs for SAP130 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SAP130 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | SAP130 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SAP130 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SAP130 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Sap130 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Sap130 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SAP130 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | SAP130 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SAP130 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100127690 30 |
|
||
| Str.15929 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.15283 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | sap130b 30 31 |
|
OneToMany | |
| sap130a 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Sap130 31 |
|
OneToOne | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for SAP130 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SAP130 Gene
- ENSEMBL:
- Gene Tree for SAP130 (if available)
- TreeFam:
- Gene Tree for SAP130 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SAP130: view image
Paralogs for SAP130 Gene
No data available for Paralogs for SAP130 Gene
Variants for SAP130 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SAP130 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 808800 | Likely Pathogenic: not provided | 128,017,847(-) | G/A | NONSENSE |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1357413 | CNV | deletion | 17803354 |
| esv2720731 | CNV | deletion | 23290073 |
| esv2720732 | CNV | deletion | 23290073 |
| esv2720733 | CNV | deletion | 23290073 |
| esv2720734 | CNV | deletion | 23290073 |
| esv2720735 | CNV | deletion | 23290073 |
| esv3560106 | CNV | deletion | 23714750 |
| esv3592372 | CNV | loss | 21293372 |
| esv4100 | CNV | loss | 18987735 |
| nsv1072026 | CNV | deletion | 25765185 |
| nsv1072447 | CNV | deletion | 25765185 |
| nsv1118876 | CNV | deletion | 24896259 |
| nsv1123382 | CNV | deletion | 24896259 |
| nsv1136409 | CNV | deletion | 24896259 |
| nsv1153553 | CNV | deletion | 26484159 |
| nsv508865 | CNV | insertion | 20534489 |
| nsv834367 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
2.34% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.65;
31.67% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SAP130 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SAP130 Gene
Disorders for SAP130 Gene
Additional Disease Information for SAP130
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for SAP130 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SAP130 Gene
Publications for SAP130 Gene
- Identification and characterization of three new components of the mSin3A corepressor complex. (PMID: 12724404) Fleischer TC … Ayer DE (Molecular and cellular biology 2003) 2 3 4 23
- Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 2 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
ExternalLinks
Products for SAP130 Gene
- Custom Antibody ServicesOriGene Antibodies for SAP130
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- Custom Assay Services
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- Search Origene for MassSpec and Protein Over-expression Lysates for SAP130
- Origene Custom Protein Services for SAP130
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SAP130
- Browse OriGene Inhibitory RNA Products For SAP130
- OriGene qPCR primer pairs for SAP130
- OriGene CRISPR knockouts for SAP130
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SAP130
- Sino Biological Human cDNA Clone for SAP130
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SAP130
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SAP130
- Abcam proteins for SAP130
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for SAP130 (AFLGC-Sap130)
- VectorBuilder Custom and pre-made DNA vectors for SAP130 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SAP130 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SAP130 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SAP130 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SAP130
- Addgene plasmids for SAP130
- antibodies-online: Show 46 available SAP130 Antibodies ranked by validation data
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- antibodies-online: Show 1 available SAP130 Elisa Kits ranked by validation data
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- Quality Products:
- antibodies-online: Show 3 available SAP130 Proteins ranked by validation data
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- Quality Products:
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SAP130
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SAP130
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SAP130
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SAP130
- Boster Bio Antibodies for SAP130
- Browse Boster Bio ELISA Kits
- Signalway Proteins for SAP130
Sources for SAP130 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
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