Aliases for SALL4 Gene
External Ids for SALL4 Gene
Previous GeneCards Identifiers for SALL4 Gene
This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
GeneCards Summary for SALL4 Gene
SALL4 (Spalt Like Transcription Factor 4) is a Protein Coding gene. Diseases associated with SALL4 include Duane-Radial Ray Syndrome and Ivic Syndrome. Among its related pathways are Wnt/beta-catenin Signaling Pathway in Leukemia and Transcriptional regulation of pluripotent stem cells. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is SALL3.
UniProtKB/Swiss-Prot Summary for SALL4 Gene
Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.