Aliases for SALL4 Gene
External Ids for SALL4 Gene
Previous GeneCards Identifiers for SALL4 Gene
This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
GeneCards Summary for SALL4 Gene
SALL4 (Spalt Like Transcription Factor 4) is a Protein Coding gene. Diseases associated with SALL4 include Duane-Radial Ray Syndrome and Ivic Syndrome. Among its related pathways are Transcriptional regulation of pluripotent stem cells and Regulation of Wnt-mediated beta catenin signaling and target gene transcription. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is SALL3.
UniProtKB/Swiss-Prot Summary for SALL4 Gene
Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.