External Ids for SAFB2 Gene
Previous GeneCards Identifiers for SAFB2 Gene
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. [provided by RefSeq, May 2016]
GeneCards Summary for SAFB2 Gene
SAFB2 (Scaffold Attachment Factor B2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and identical protein binding. An important paralog of this gene is SAFB.
UniProtKB/Swiss-Prot Summary for SAFB2 Gene
Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.