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Aliases for S100A7L2 Gene

Aliases for S100A7L2 Gene

  • S100 Calcium Binding Protein A7 Like 2 2 3 5
  • S100a7b 3 4
  • S100 Calcium Binding Protein A7-Like 2 2
  • S100 Calcium-Binding Protein A7-Like 2 4
  • Protein S100-A7-Like 2 3

External Ids for S100A7L2 Gene

Previous GeneCards Identifiers for S100A7L2 Gene

  • GC01M150626
  • GC01U901079
  • GC01M151677
  • GC01M124772

Summaries for S100A7L2 Gene

GeneCards Summary for S100A7L2 Gene

S100A7L2 (S100 Calcium Binding Protein A7 Like 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is S100A7A.

Additional gene information for S100A7L2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for S100A7L2 Gene

Genomics for S100A7L2 Gene

GeneHancer (GH) Regulatory Elements for S100A7L2 Gene

Promoters and enhancers for S100A7L2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I153439 Promoter 0.5 EPDnew 550.8 +0.0 30 0.1 S100A7L2 S100A7P1
GH01I153531 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 5.3 -95.1 -95103 8.2 HDGF PKNOX1 FOXA2 SMAD1 ARID4B SIN3A ZNF48 GLIS2 ARID2 ZNF143 ENSG00000238279 PIR41635 S100A6 S100A3 INTS3 CHTOP UBAP2L ENSG00000272654 RN7SL44P CREB3L4
GH01I153561 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 2.5 -125.5 -125534 8.8 HDGF PKNOX1 ARNT ARID4B NEUROD1 SIN3A DMAP1 ZNF2 YY1 ZNF213 S100A2 S100A6 S100A3 S100A5 ENSG00000238279 S100A16 S100A13 S100A14 SNAPIN S100A1
GH01I153606 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 1.7 -172.4 -172432 11.6 HDGF PKNOX1 CLOCK FOXA2 MLX ARID4B NEUROD1 SIN3A DMAP1 ZBTB7B S100A16 S100A14 S100A1 SNAPIN ILF2 ENSG00000233222 ENSG00000243613 INTS3 S100A13 ENSG00000272030
GH01I153578 Enhancer 0.4 FANTOM5 11.1 -137.2 -137233 0.2 SCRT1 ZNF512 PRDM10 S100A3 S100A7L2 PGLYRP3 PIR44602 S100A2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around S100A7L2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the S100A7L2 gene promoter:

Genomic Locations for S100A7L2 Gene

Genomic Locations for S100A7L2 Gene
3,033 bases
Minus strand

Genomic View for S100A7L2 Gene

Genes around S100A7L2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
S100A7L2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for S100A7L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for S100A7L2 Gene

Proteins for S100A7L2 Gene

  • Protein details for S100A7L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein S100-A7-like 2
    Protein Accession:

    Protein attributes for S100A7L2 Gene

    101 amino acids
    Molecular mass:
    11302 Da
    Quaternary structure:
    No Data Available

neXtProt entry for S100A7L2 Gene

Post-translational modifications for S100A7L2 Gene

No Post-translational modifications

Other Protein References for S100A7L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for S100A7L2 Gene

Domains & Families for S100A7L2 Gene

Gene Families for S100A7L2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for S100A7L2 Gene

Suggested Antigen Peptide Sequences for S100A7L2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the S-100 family.
  • Belongs to the S-100 family.
genes like me logo Genes that share domains with S100A7L2: view

Function for S100A7L2 Gene

Phenotypes From GWAS Catalog for S100A7L2 Gene

Gene Ontology (GO) - Molecular Function for S100A7L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding IEA --
GO:0046872 metal ion binding IEA --
GO:0046914 transition metal ion binding IEA --
genes like me logo Genes that share ontologies with S100A7L2: view

Phenotypes for S100A7L2 Gene

genes like me logo Genes that share phenotypes with S100A7L2: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for S100A7L2 Gene

Localization for S100A7L2 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for S100A7L2 gene
Compartment Confidence
extracellular 5
cytosol 2
mitochondrion 1
nucleus 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for S100A7L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 21805676
genes like me logo Genes that share ontologies with S100A7L2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for S100A7L2 Gene

Pathways & Interactions for S100A7L2 Gene

SuperPathways for S100A7L2 Gene

No Data Available

Interacting Proteins for S100A7L2 Gene

Selected Interacting proteins: Q5SY68-S1A7B_HUMAN for S100A7L2 Gene via UniProtKB

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for S100A7L2 Gene


No data available for Pathways by source and SIGNOR curated interactions for S100A7L2 Gene

Drugs & Compounds for S100A7L2 Gene

No Compound Related Data Available

Transcripts for S100A7L2 Gene

mRNA/cDNA for S100A7L2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for S100A7L2 Gene

No ASD Table

Relevant External Links for S100A7L2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for S100A7L2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for S100A7L2 Gene

Protein differential expression in normal tissues from HIPED for S100A7L2 Gene

This gene is overexpressed in Esophagus (65.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for S100A7L2 Gene

Protein tissue co-expression partners for S100A7L2 Gene

NURSA nuclear receptor signaling pathways regulating expression of S100A7L2 Gene:


SOURCE GeneReport for Unigene cluster for S100A7L2 Gene:

genes like me logo Genes that share expression patterns with S100A7L2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for S100A7L2 Gene

Orthologs for S100A7L2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for S100A7L2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia S100A7L2 33 34
  • 99.7 (n)
(Bos Taurus)
Mammalia -- 34
  • 52 (a)
S100A7 34
  • 50 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 25 (a)
Species where no ortholog for S100A7L2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for S100A7L2 Gene

Gene Tree for S100A7L2 (if available)
Gene Tree for S100A7L2 (if available)

Paralogs for S100A7L2 Gene

Paralogs for S100A7L2 Gene

(6) SIMAP similar genes for S100A7L2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with S100A7L2: view

Variants for S100A7L2 Gene

Sequence variations from dbSNP and Humsavar for S100A7L2 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000459791 -- 153,438,517(-) C/T intron_variant
rs1002203137 -- 153,441,861(-) T/C upstream_transcript_variant
rs1002372993 -- 153,438,532(-) C/T intron_variant
rs1003805382 -- 153,440,788(-) T/C upstream_transcript_variant
rs1005545693 -- 153,441,587(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for S100A7L2 Gene

Variant ID Type Subtype PubMed ID
esv33204 CNV gain 17666407
nsv1002705 CNV gain 25217958
nsv831603 CNV gain 17160897

Variation tolerance for S100A7L2 Gene

Gene Damage Index Score: 2.17; 39.35% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for S100A7L2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for S100A7L2 Gene

Disorders for S100A7L2 Gene

Additional Disease Information for S100A7L2

No disorders were found for S100A7L2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for S100A7L2 Gene

Publications for S100A7L2 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
  2. Genomic and phylogenetic analysis of the S100A7 (Psoriasin) gene duplications within the region of the S100 gene cluster on human chromosome 1q21. (PMID: 12664160) Kulski JK … Bellgard M (Journal of molecular evolution 2003) 3 4 58
  3. Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection. (PMID: 21805676) Fornander L … Lindahl M (Proteomics. Clinical applications 2011) 3 58

Products for S100A7L2 Gene

Sources for S100A7L2 Gene

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