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The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located... See more...
Aliases for S100A4 Gene
Aliases for S100A4 Gene
- S100 Calcium Binding Protein A4 2 3 5
- S100 Calcium-Binding Protein A4 (Calcium Protein, Calvasculin, Metastasin, Murine Placental Homolog) 2 3
- Placental Calcium-Binding Protein 3 4
- Fibroblast-Specific Protein-1 2 3
- Calcium Placental Protein 2 3
- Murine Placental Homolog 2 3
- Protein S100-A4 3 4
- Metastasin 1 2 3
- Protein Mts1 3 4
- Calvasculin 2 4
- PEL98 2 3
External Ids for S100A4 Gene
- HGNC: 10494
- Entrez Gene: 6275
- Ensembl: ENSG00000196154
- OMIM: 114210
- UniProtKB: P26447
Previous HGNC Symbols for S100A4 Gene
- MTS1
- CAPL
Previous GeneCards Identifiers for S100A4 Gene
- GC01M151332
- GC01M149298
- GC01M150343
- GC01M150784
- GC01M150585
- GC01M150330
- GC01M151783
- GC01M153517
- GC01M124879
- GC01M153518
Summaries for S100A4 Gene
-
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for S100A4 Gene
S100A4 (S100 Calcium Binding Protein A4) is a Protein Coding gene. Diseases associated with S100A4 include Bile Duct Adenocarcinoma and Small Intestine Adenocarcinoma. Among its related pathways are Ca, cAMP and Lipid Signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is S100A2.
Additional gene information for S100A4 Gene
- HGNC(10494)
- Entrez Gene(6275)
- Ensembl(ENSG00000196154)
- OMIM(114210)
- UniProtKB(P26447)
- Open Targets Platform(ENSG00000196154)
- Monarch Initiative
- Search for S100A4 at DataMed
- Search for S100A4 at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for S100A4 Gene
Genomics for S100A4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for S100A4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around S100A4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for S100A4
- Top Transcription factor binding sites by QIAGEN in the S100A4 gene promoter:
-
- AML1a
- ATF-2
- c-Jun
Genomic Locations for S100A4 Gene
Genomic Locations for S100A4 Gene
- chr1:153,543,613-153,550,136
- (GRCh38/hg38)
- Size:
- 6,524 bases
- Orientation:
- Minus strand
- chr1:153,516,089-153,522,612
- (GRCh37/hg19)
- Size:
- 6,524 bases
- Orientation:
- Minus strand
Genomic View for S100A4 Gene
Genes around S100A4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q21.3 by HGNC
- 1q21.3 by Entrez Gene
- 1q21.3 by Ensembl
S100A4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for S100A4 Gene
Proteins for S100A4 Gene
-
Protein details for S100A4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P26447-S10A4_HUMAN
- Recommended name:
- Protein S100-A4
- Protein Accession:
- P26447
- A8K7R8
- D3DV46
- Q6ICP8
Protein attributes for S100A4 Gene
- Size:
- 101 amino acids
- Molecular mass:
- 11729 Da
- Quaternary structure:
-
- Homodimer. Interacts with PPFIBP1 in a calcium-dependent mode.
Protein Expression for S100A4 Gene
Post-translational modifications for S100A4 Gene
Other Protein References for S100A4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- NSJ Bioreagents S100A4 Antibody / FSP1 (Mouse Monoclonal)
- Alomone Labs, Ltd. Anti-Sortilin (extracellular)-FITC Antibody
-
Custom Antibody ServicesOriGene Antibodies for S100A4
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-
Abcam antibodies for S100A4
- Invitrogen Antibodies for S100A4 (AFLGC-S100a4)
-
Santa Cruz Biotechnology (SCBT) Antibodies for S100A4
- Sino Biological Antibodies for S100A4
Protein Products
- G Biosciences Human S100A4, Lyophilized
- Search Origene for MassSpec and Protein Over-expression Lysates for S100A4
- Origene Custom Protein Services for S100A4
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- Sino Biological Recombinant Proteins for S100A4
- ProSpec Recombinant Proteins for S100A4
-
Abcam proteins for S100A4
Assay Products
- RayBiotech Custom Human S100A4 ELISA
- antibodies-online: Show 44 available s100a4 Elisa Kits ranked by validation data
- Compare Top s100a4 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for S100A4 Gene
Domains & Families for S100A4 Gene
Gene Families for S100A4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for S100A4 Gene
- InterPro:
- Blocks:
-
- Calcium-binding protein, S-100/ICaBP type
- ProtoNet:
Suggested Antigen Peptide Sequences for S100A4 Gene
- GenScript: Design optimal peptide antigens:
-
- S100 calcium-binding protein A4 (S10A4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P26447- Family:
-
- Belongs to the S-100 family.
Function for S100A4 Gene
Molecular function for S100A4 Gene
- GENATLAS Biochemistry:
- S100 calcium binding protein A4,murine placental homolog,epidermal differentiation complex,possessing metastasis-inducing capabilities,involved in the regulation of cell cycle progression,modulating intercellular adhesion,and invasive and metastatic properties of cancer cells
Phenotypes From GWAS Catalog for S100A4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | HDA | 22658674 |
| GO:0003779 | actin binding | IEA | -- |
| GO:0005509 | calcium ion binding | TAS,IEA | -- |
| GO:0005515 | protein binding | IPI | 14640694 |
| GO:0042802 | identical protein binding | IPI | 20421509 |
Phenotypes for S100A4 Gene
- MGI mutant phenotypes for S100A4:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for S100A4:
Animal Models for S100A4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for S100A4 - Select products 50% OFF >
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-
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miRNA for S100A4 Gene
- miRTarBase miRNAs that target S100A4
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for S100A4 - Select products 50% OFF >
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Cell Line Products
-
Horizon Cell Lines for S100A4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for S100A4 Gene
Localization for S100A4 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 4 |
| cytoskeleton | 3 |
| plasma membrane | 2 |
| mitochondrion | 2 |
| endoplasmic reticulum | 2 |
| peroxisome | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Plasma membrane (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | HDA | 27068509 |
| GO:0005615 | extracellular space | HDA | 22664934 |
| GO:0005634 | nucleus | IDA | 12118070 |
| GO:0043005 | neuron projection | IEA | -- |
| GO:0048471 | perinuclear region of cytoplasm | IDA | 15033494 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for S100A4 Gene
Pathways & Interactions for S100A4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Ca, cAMP and Lipid Signaling | ||
Pathways by source for S100A4 Gene
1 Cell Signaling Technology pathway for S100A4 Gene
Interacting Proteins for S100A4 Gene
Selected Interacting proteins:
P26447-S10A4_HUMAN
ENSP00000357705
for S100A4 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for S100A4
SIGNOR curated interactions for S100A4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001837 | epithelial to mesenchymal transition | TAS | 14679171 |
| GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | IDA | 15033494 |
Drugs & Compounds for S100A4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Trifluoperazine | Approved, Investigational | Pharma | Antagonist, Target, inhibitor | 7 | ||
| Copper | Approved, Investigational | Pharma | Target | 249 | ||
| Niclosamide | Approved, Investigational, Vet_approved | Pharma | STAT3 inhibitor; also inhibits mTORC1 signaling | 16 | ||
| Calcium | Nutra | 6556 | ||||
| Anthelmintics | Pharma | 486 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
- G Biosciences Human S100A4, Lyophilized
Transcripts for S100A4 Gene
mRNA/cDNA for S100A4 Gene
- 2 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000354332 566 nts (view in UCSC)
- ENST00000368714 531 nts (view in UCSC)
- ENST00000368715 573 nts (view in UCSC)
- ENST00000368716 513 nts (view in UCSC)
- ENST00000468373 537 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for S100A4 - Select products 50% OFF >
- * S100A4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for S100A4
-
Santa Cruz Biotechnology (SCBT) CRISPR for S100A4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for S100A4
- Browse OriGene Inhibitory RNA Products For S100A4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for S100A4
Clone Products
- Applied Biological Materials (abm): Clones for S100A4 - Select products 50% OFF >
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- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
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- MG225750
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- RG201616
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- RR203138
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- MR225750L3V
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- RC201616L1V
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- RR203138L3V
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for S100A4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for S100A4
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | · | 5f |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | |||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||
| SP5: | - | - | - | - | |||||||||||||||||||||||||
| SP6: | - | - | - | ||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||
| SP8: | - |
Relevant External Links for S100A4 Gene
- GeneLoc Exon Structure for
- S100A4
Expression for S100A4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Fibroblasts
- Dermis (Integumentary System)
- Bone (Muscoskeletal System)
-
Hair (Integumentary System)
- Bulge Stem Cells Bulge
-
Neural Tube (Nervous System)
- Adult Oligodendrocyte Precursor Cells Cortical Sub Ventricular Zone
-
Brain (Nervous System)
- Adult Oligodendrocyte Precursor Cells Cortical Sub Ventricular Zone
-
Eye (Sensory Organs)
- Mature Endothelial Cells Corneal Endothelium
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Corneal Endothelium
-
Heart (Cardiovascular System)
- Cardiac Fibroblasts Myocardium
- Thymus (Hematopoietic System)
- Tendon & Ligament
- Intestine
- Neural Crest (Gastrulation Derivatives)
- Lateral Plate Mesoderm (Gastrulation Derivatives)
- Paraxial Mesoderm (Gastrulation Derivatives)
- Mesenchymal Stem Cells (Uncategorized)
- Umbilical Cord (Extraembryonic Tissues)
- Cartilage (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for S100A4 Gene
This gene is overexpressed in Whole Blood (x17.6) and Artery - Aorta (x4.2).
This gene is overexpressed in Tlymphocyte (6.9), NK cells (6.8), Monocytes (6.7), and CD4 Tcells (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for S100A4 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for S100A4
SOURCE GeneReport for Unigene cluster for S100A4 Gene:
Hs.654444mRNA Expression by UniProt/SwissProt for S100A4 Gene:
P26447-S10A4_HUMAN
Tissue specificity:
Ubiquitously expressed.
Evidence on tissue expression from TISSUES for S100A4 Gene
- Liver(4.8)
- Blood(4.8)
- Heart(4.7)
- Spleen(4.6)
- Muscle(3.6)
- Bone marrow(3.6)
- Lung(3.6)
- Intestine(3.4)
- Skin(3.3)
- Lymph node(3.3)
- Eye(3.3)
- Kidney(3.3)
- Stomach(2.7)
- Gall bladder(2.6)
- Thyroid gland(2.6)
- Nervous system(2.5)
- Pancreas(2.4)
- Adrenal gland(2.2)
Primer Products
-
OriGene qPCR primer pairs for S100A4
-
OriGene qPCR primer pairs and template standards for S100A4
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for S100A4 Gene
Orthologs for S100A4 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | S100A4 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | S100A4 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | S100A4 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | S100a4 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | S100a4 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | S100A4 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | S100A4 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | S100A4 30 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | icn 30 |
|
- Species where no ortholog for S100A4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for S100A4 Gene
- ENSEMBL:
- Gene Tree for S100A4 (if available)
- TreeFam:
- Gene Tree for S100A4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for S100A4: view image
Paralogs for S100A4 Gene
Paralogs for S100A4 Gene
(20) SIMAP similar genes for S100A4 Gene using alignment to 1 proteins:
- S10A4_HUMAN
Variants for S100A4 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for S100A4 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 736033 | Benign: not provided | 153,543,861(-) | G/A | SYNONYMOUS_VARIANT | |
| 772816 | Benign: not provided | 153,543,882(-) | G/A | SYNONYMOUS_VARIANT | |
| 777935 | Benign: not provided | 153,543,831(-) | G/A | SYNONYMOUS_VARIANT | |
| 786858 | Benign: not provided | 153,544,735(-) | C/T | SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3587584 | CNV | gain | 21293372 |
| esv3587591 | CNV | gain | 21293372 |
| nsv1002705 | CNV | gain | 25217958 |
| nsv831603 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
45.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.26;
5.83% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for S100A4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- S100A4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for S100A4 Gene
Disorders for S100A4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| bile duct adenocarcinoma |
|
|
| small intestine adenocarcinoma |
|
|
| spastic paraplegia 3, autosomal dominant |
|
|
| follicular adenoma |
|
|
| pleural tuberculosis |
|
|
Search S100A4 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for S100A4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Tumor Gene Database
- (TGDB)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for S100A4 Gene
Publications for S100A4 Gene
- Phenothiazines inhibit S100A4 function by inducing protein oligomerization. (PMID: 20421509) Malashkevich VN … Bresnick AR (Proceedings of the National Academy of Sciences of the United States of America 2010) 3 23 26
- Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1). (PMID: 11836260) Kriajevska M … Lukanidin E (The Journal of biological chemistry 2002) 3 4 23
- Solution structure of human Mts1 (S100A4) as determined by NMR spectroscopy. (PMID: 12379109) Vallely KM … Weber DJ (Biochemistry 2002) 3 4 23
- Calcyclin and calvasculin exist in human platelets. (PMID: 1482346) Tomida Y … Hidaka H (Biochemical and biophysical research communications 1992) 3 4 23
- Expression status of S100A14 and S100A4 correlates with metastatic potential and clinical outcome in colorectal cancer after surgery. (PMID: 19956863) Wang HY … Lu YY (Oncology reports 2010) 3 23
ExternalLinks
Products for S100A4 Gene
- Custom Antibody ServicesOriGene Antibodies for S100A4
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- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for S100A4
- Origene Custom Protein Services for S100A4
- Origene shrna, sirna, and RNAi products in human, mouse, rat for S100A4
- Browse OriGene Inhibitory RNA Products For S100A4
- OriGene qPCR primer pairs for S100A4
- OriGene qPCR primer pairs and template standards for S100A4
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- RR203138
- RR203138L3
- RR203138L4
- MR225750L3V
- MR225750L4V
- RC201616L1V
- RC201616L2V
- RC201616L3V
- RC201616L4V
- RC203035L1V
- RC203035L2V
- RC203035L3V
- RC203035L4V
- RR203138L3V
- RR203138L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- VectorBuilder Custom and pre-made DNA vectors for S100A4 (ie. gene expression, shRNA knockdown, CRISPR)
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- antibodies-online: Show 37 available s100a4 Antibodies ranked by validation data
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- Santa Cruz Biotechnology (SCBT) Antibodies for S100A4
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Sources for S100A4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB