Aliases for RXFP2 Gene
External Ids for RXFP2 Gene
Previous HGNC Symbols for RXFP2 Gene
Previous GeneCards Identifiers for RXFP2 Gene
This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
GeneCards Summary for RXFP2 Gene
RXFP2 (Relaxin/Insulin Like Family Peptide Receptor 2) is a Protein Coding gene. Diseases associated with RXFP2 include Cryptorchidism, Unilateral Or Bilateral and Testicular Cancer. Among its related pathways are Peptide ligand-binding receptors and Relaxin signaling pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and protein-hormone receptor activity. An important paralog of this gene is RXFP1.
UniProtKB/Swiss-Prot for RXFP2 Gene
Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).