Aliases for RUSC1 Gene
External Ids for RUSC1 Gene
Previous GeneCards Identifiers for RUSC1 Gene
GeneCards Summary for RUSC1 Gene
RUSC1 (RUN And SH3 Domain Containing 1) is a Protein Coding gene. Among its related pathways are Trk receptor signaling mediated by the MAPK pathway. Gene Ontology (GO) annotations related to this gene include actin binding and SH3/SH2 adaptor activity. An important paralog of this gene is RUSC2.
UniProtKB/Swiss-Prot Summary for RUSC1 Gene
Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.