Aliases for RTF1 Gene
Aliases for RTF1 Gene
- RTF1 Homolog, Paf1/RNA Polymerase II Complex Component 2 3 5
- KIAA0252 2 3 4
- Rtf1, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) 2
- Rtf1, Paf1/RNA Polymerase II Complex Component, Homolog 3
- RNA Polymerase-Associated Protein RTF1 Homolog 3
- Ortholog Of Mouse Gene Trap Locus 7 3
- GTL7 3
External Ids for RTF1 Gene
- HGNC: 28996
- Entrez Gene: 23168
- Ensembl: ENSG00000137815
- OMIM: 611633
- UniProtKB: Q92541
Previous HGNC Symbols for RTF1 Gene
- KIAA0252
Previous GeneCards Identifiers for RTF1 Gene
- GC15P039497
- GC15P041709
- GC15P018557
Summaries for RTF1 Gene
-
This locus may represent a gene involved in regulation of transcription elongation and chromatin remodeling, based on studies of similar proteins in other organisms. The encoded protein may bind single-stranded DNA. [provided by RefSeq, Sep 2010]
GeneCards Summary for RTF1 Gene
RTF1 (RTF1 Homolog, Paf1/RNA Polymerase II Complex Component) is a Protein Coding gene. Among its related pathways are Formation of HIV-1 elongation complex containing HIV-1 Tat and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include single-stranded DNA binding.
UniProtKB/Swiss-Prot for RTF1 Gene
-
Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and Ser-2- and Ser-5-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 Lys-4 (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of Lys-120 of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3 end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Binds single-stranded DNA. Required for maximal induction of heat-shock genes. Required for the trimethylation of histone H3 Lys-4 (H3K4me3) on genes involved in stem cell pluripotency; this function is synergistic with CXXC1 indicative for an involvement of a SET1 complex (By similarity).
Additional gene information for RTF1 Gene
- Monarch Initiative
- Search for RTF1 at DataMed
- Search for RTF1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RTF1 Gene
Genomics for RTF1 Gene
GeneHancer (GH) Regulatory Elements for RTF1 Gene
Promoters and enhancers for RTF1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around RTF1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the RTF1 gene promoter:
-
- E2F-1
- E2F
- p53
- NF-1
- SRY
- Nkx6-1
- GATA-1
- HOXA9
- HOXA9B
- Meis-1
Regulatory Element Products
Genomic Locations for RTF1 Gene
Genomic Locations for RTF1 Gene
- chr15:41,408,408-41,483,563
- (GRCh38/hg38)
- Size:
- 75,156 bases
- Orientation:
- Plus strand
- chr15:41,700,606-41,775,761
- (GRCh37/hg19)
- Size:
- 75,156 bases
- Orientation:
- Plus strand
Genomic View for RTF1 Gene
Genes around RTF1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q15.1 by Entrez Gene
- 15q15.1 by HGNC
- 15q15.1 by Ensembl
RTF1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RTF1 Gene
Proteins for RTF1 Gene
-
Protein details for RTF1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q92541-RTF1_HUMAN
- Recommended name:
- RNA polymerase-associated protein RTF1 homolog
- Protein Accession:
- Q92541
- Q96BX6
Protein attributes for RTF1 Gene
- Size:
- 710 amino acids
- Molecular mass:
- 80313 Da
- Quaternary structure:
-
- Component of the PAF1 complex, which consists of CDC73, PAF1, LEO1, CTR9, RTF1 and WDR61; the association of RTF1 appears to be less stable than that of other subunits. At least in HeLa cells a N-terminal shorter form of RTF1 is also found in the complex (PubMed:20178742). The PAF1 complex interacts with PHF5A (By similarity).
- SequenceCaution:
-
- Sequence=AAH15052.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAA13382.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for RTF1 Gene
Post-translational modifications for RTF1 Gene
Other Protein References for RTF1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for RTF1
- Novus Biologicals Antibodies for RTF1
-
Abcam antibodies for RTF1
- Invitrogen Antibodies for RTF1 (AFLGC-RTF1)
- GeneTex RTF1 Antibody for RTF1
-
Boster Bio Antibodies for RTF1
Protein Products
-
OriGene Purified Proteins for RTF1
- Search Origene for MassSpec and Protein Over-expression Lysates for RTF1
- Origene Custom Protein Services for RTF1
- Search GeneTex for Proteins for RTF1
-
Abcam proteins for RTF1
Assay Products
No data available for DME Specific Peptides for RTF1 Gene
Domains & Families for RTF1 Gene
Gene Families for RTF1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for RTF1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RTF1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q92541- Domain:
-
- The Plus3 domain mediates single-stranded DNA-binding.
Function for RTF1 Gene
Molecular function for RTF1 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and Ser-2- and Ser-5-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 Lys-4 (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of Lys-120 of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3 end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Binds single-stranded DNA. Required for maximal induction of heat-shock genes. Required for the trimethylation of histone H3 Lys-4 (H3K4me3) on genes involved in stem cell pluripotency; this function is synergistic with CXXC1 indicative for an involvement of a SET1 complex (By similarity).
Phenotypes From GWAS Catalog for RTF1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001076 | transcription factor activity, RNA polymerase II transcription factor binding | IBA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003697 | single-stranded DNA binding | IDA | 18184592 |
| GO:0003723 | RNA binding | HDA | 22658674 |
| GO:0005515 | protein binding | IPI | 15923622 |
Phenotypes for RTF1 Gene
- MGI mutant phenotypes for RTF1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RTF1:
-
- Increased shRNA abundance (Z-score > 2)
- Increased transcriptional activity
- Decreased shRNA abundance (Z-score < -2)
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Reduced mammosphere formation
- Decreased viability with TRAIL
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Decreased interferon-beta reporter expression
- Downregulation of NF-kappaB pathway after TNFalpha stimulation
- Downregulation of NF-kappaB pathway after LMP1 stimulation
- shRNA abundance <= 50%
Animal Models for RTF1 Gene
- MGI Knock Outs for RTF1:
-
- Rtf1 Rtf1<tm1a(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RTF1
-
CRISPR Products
-
OriGene CRISPR knockouts for RTF1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RTF1
- genomics-online: gRNA clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
- Applied Biological Materials CRISPR for RTF1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RTF1
- GenScript: Design CRISPR guide RNA sequences for RTF1
miRNA for RTF1 Gene
- miRTarBase miRNAs that target RTF1
-
- hsa-mir-26b-5p (MIRT029127)
- hsa-mir-196b-5p (MIRT042673)
- hsa-mir-26a-5p (MIRT072125)
- hsa-mir-5096 (MIRT521273)
- hsa-mir-6855-5p (MIRT521274)
- hsa-mir-3170 (MIRT521275)
- hsa-mir-411-5p (MIRT521276)
- hsa-mir-3152-3p (MIRT521277)
- hsa-mir-6832-5p (MIRT521278)
- hsa-mir-193b-5p (MIRT521279)
- hsa-mir-509-3p (MIRT521280)
- hsa-mir-1273f (MIRT521281)
- hsa-mir-10b-3p (MIRT521282)
- hsa-mir-6890-5p (MIRT521283)
- hsa-mir-6812-3p (MIRT614785)
- hsa-mir-4639-3p (MIRT614786)
- hsa-mir-4789-3p (MIRT614787)
- hsa-mir-466 (MIRT627655)
- hsa-mir-4672 (MIRT627656)
- hsa-mir-3941 (MIRT630269)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RTF1
- Browse OriGene Inhibitory RNA Products For RTF1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RTF1
- genomics-online: shRNA clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
Clone Products
- Sino Biological Human cDNA Clone for RTF1
- Addgene plasmids for RTF1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RTF1
- Applied Biological Materials Clones for RTF1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RTF1 Gene
Localization for RTF1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RTF1 Gene
- Nucleus, nucleoplasm.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
- Cytosol (2)
- Nucleus (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005730 | nucleolus | IEA | -- |
| GO:0016593 | Cdc73/Paf1 complex | IDA,IEA | 20178742 |
Pathways & Interactions for RTF1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Formation of HIV-1 elongation complex containing HIV-1 Tat | ||
| 2 | Protein ubiquitination | ||
| 3 | Metabolism of proteins | ||
| 4 | Chromatin Regulation / Acetylation | ||
| 5 | Gene Expression |
.48
|
|
Pathways by source for RTF1 Gene
1 BioSystems pathway for RTF1 Gene
1 Cell Signaling Technology pathway for RTF1 Gene
Interacting Proteins for RTF1 Gene
Selected Interacting proteins:
ENSP00000374280
Q92541-RTF1_HUMAN
for RTF1 Gene via
STRING
UniProtKB
IID
GPS-Prot Interaction Network for RTF1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | ISS | -- |
| GO:0001711 | endodermal cell fate commitment | ISS,IEA | -- |
| GO:0001832 | blastocyst growth | IEA | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
No data available for SIGNOR curated interactions for RTF1 Gene
Transcripts for RTF1 Gene
mRNA/cDNA for RTF1 Gene
- (1) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (311) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000558298 327 bps (uc059hyi.1)
- ENST00000389629 5021 bps (uc001zny.3)
- ENST00000462276 485 bps (uc059hyj.1)
- ENST00000473214 475 bps (uc059hyl.1)
- ENST00000560447 551 bps (uc059hym.1)
Unigene Clusters for RTF1 Gene
- Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae):
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for RTF1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RTF1
- genomics-online: gRNA clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
- Applied Biological Materials CRISPR for RTF1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RTF1
- GenScript: Design CRISPR guide RNA sequences for RTF1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RTF1
- Browse OriGene Inhibitory RNA Products For RTF1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RTF1
- genomics-online: shRNA clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
Clone Products
- Sino Biological Human cDNA Clone for RTF1
- Addgene plasmids for RTF1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RTF1
- Applied Biological Materials Clones for RTF1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for RTF1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Lung (32.3) and Peripheral blood mononuclear cells (9.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RTF1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of RTF1 Gene:
RTF1SOURCE GeneReport for Unigene cluster for RTF1 Gene:
Hs.511096Evidence on tissue expression from TISSUES for RTF1 Gene
- Nervous system(4.6)
Primer Products
-
OriGene qPCR primer pairs for RTF1
- genomics-online: primer clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RTF1 Gene
Orthologs for RTF1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RTF1 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | RTF1 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | RTF1 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | RTF1 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | RTF1 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Rtf1 16 34 33 |
|
||
| chicken (Gallus gallus) |
Aves | RTF1 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | RTF1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | rtf1 33 |
|
||
| Str.16458 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.16706 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | rtf1 34 33 |
|
OneToOne | |
| Dr.15115 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2044 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Rtf1 34 33 |
|
OneToMany | |
| CG31703 34 |
|
OneToMany | |||
| CG31702 34 |
|
OneToMany | |||
| CG12498 34 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | F25B3.6 34 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RTF1 34 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.1372 34 |
|
OneToOne |
- Species where no ortholog for RTF1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for RTF1 Gene
- ENSEMBL:
- Gene Tree for RTF1 (if available)
- TreeFam:
- Gene Tree for RTF1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RTF1: view image
Paralogs for RTF1 Gene
No data available for Paralogs for RTF1 Gene
Variants for RTF1 Gene
| SNP ID | Clin | Chr 15 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000117666 | -- | 41,479,307(+) | G/T | intron_variant | |
| rs1000118948 | -- | 41,458,789(+) | A/T | intron_variant | |
| rs1000134767 | -- | 41,417,815(+) | T/C | intron_variant | |
| rs1000148385 | -- | 41,452,449(+) | C/G | intron_variant | |
| rs1000198900 | -- | 41,424,004(+) | T/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2580n100 | CNV | gain | 25217958 |
| esv2674168 | CNV | deletion | 23128226 |
| esv3636243 | CNV | loss | 21293372 |
| esv3636244 | CNV | loss | 21293372 |
| nsv1039283 | CNV | gain | 25217958 |
| nsv1505 | CNV | insertion | 18451855 |
| nsv524476 | CNV | loss | 19592680 |
| nsv569232 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
18.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.88;
18.37% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RTF1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RTF1 Gene
Disorders for RTF1 Gene
Additional Disease Information for RTF1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for RTF1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RTF1 Gene
Publications for RTF1 Gene
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt KT … Blagoev B (Science signaling 2011) 3 4 58
- The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS. (PMID: 20178742) Kim J … Roeder RG (Cell 2010) 3 4 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. (PMID: 19345177) Ding L … Buchholz F (Cell stem cell 2009) 3 4 58
- Structure and DNA binding of the human Rtf1 Plus3 domain. (PMID: 18184592) de Jong RN … Folkers GE (Structure (London, England : 1993) 2008) 3 4 58
Products for RTF1 Gene
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for RTF1 (AFLGC-RTF1)
- Cyagen custom Knockout/knockin (KOKI) mouse models for RTF1
- Addgene plasmids for RTF1
- antibodies-online: Search results for 68 available RTF1 Antibodies ranked by validation data
- Compare Top RTF1 Antibodies
- antibodies-online: Search results for 2 available RTF1 Elisa Kits ranked by validation data
- Compare Top RTF1 Elisa Kits
- Recommended
- antibodies-online: Search results for 3 available RTF1 Proteins ranked by validation data
- Compare Top RTF1 Proteins
- GeneTex RTF1 Antibody for RTF1
- Search GeneTex for Proteins for RTF1
- genomics-online: cdna clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
- orf clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
- genomics-online: gRNA clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
- genomics-online: primer clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
- genomics-online: shRNA clones - Search results for 88 available RTF1 gene related products
- Overview of 88 available RTF1 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RTF1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RTF1
- GeneCopoeia miRNA 3'UTR Target clone products for RTF1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RTF1
- Boster Bio Antibodies for RTF1
- Browse Boster Bio ELISA Kits
Sources for RTF1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt