Aliases for RRN3 Gene
External Ids for RRN3 Gene
Previous GeneCards Identifiers for RRN3 Gene
GeneCards Summary for RRN3 Gene
RRN3 (RRN3 Homolog, RNA Polymerase I Transcription Factor) is a Protein Coding gene. Diseases associated with RRN3 include Noonan Syndrome 1. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and RNA Polymerase I Promoter Escape. Gene Ontology (GO) annotations related to this gene include binding and RNA polymerase binding.
UniProtKB/Swiss-Prot Summary for RRN3 Gene
Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction (By similarity).