Aliases for RRAS Gene
External Ids for RRAS Gene
Previous GeneCards Identifiers for RRAS Gene
The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]
GeneCards Summary for RRAS Gene
RRAS (RAS Related) is a Protein Coding gene. Diseases associated with RRAS include Juvenile Myelomonocytic Leukemia and Noonan Syndrome 1. Among its related pathways are NGF Pathway and Integrin Pathway. Gene Ontology (GO) annotations related to this gene include GTP binding. An important paralog of this gene is RRAS2.
UniProtKB/Swiss-Prot Summary for RRAS Gene
Regulates the organization of the actin cytoskeleton (PubMed:16537651, PubMed:18270267). With OSPBL3, modulates integrin beta-1 (ITGB1) activity (PubMed:18270267).