Aliases for RRAD Gene
External Ids for RRAD Gene
Previous GeneCards Identifiers for RRAD Gene
GeneCards Summary for RRAD Gene
RRAD (RRAD, Ras Related Glycolysis Inhibitor And Calcium Channel Regulator) is a Protein Coding gene. Diseases associated with RRAD include Benign Pleural Mesothelioma and Type 2 Diabetes Mellitus. Among its related pathways are Angiopoietin Like Protein 8 Regulatory Pathway. Gene Ontology (GO) annotations related to this gene include GTP binding and calmodulin binding. An important paralog of this gene is GEM.
UniProtKB/Swiss-Prot Summary for RRAD Gene
May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.