Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar ... See more...

Aliases for RPS6KC1 Gene

Aliases for RPS6KC1 Gene

  • Ribosomal Protein S6 Kinase C1 2 3 5
  • Ribosomal S6 Kinase-Like Protein With Two PSK Domains 118 KDa Protein 3 4
  • Ribosomal Protein S6 Kinase Delta-1 3 4
  • 52 KDa Ribosomal Protein S6 Kinase 3 4
  • SPHK1-Binding Protein 3 4
  • S6K-Delta-1 3 4
  • HumS6PKh1 2 3
  • RPK118 3 4
  • RSKL1 2 3
  • Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1 3
  • Ribosomal Protein S6 Kinase, 52kD, Polypeptide 1 2
  • EC 2.7.11.1 4
  • RPS6KC1 5
  • S6PKh1 3

External Ids for RPS6KC1 Gene

Previous GeneCards Identifiers for RPS6KC1 Gene

  • GC01P212070
  • GC01P209067
  • GC01P209840
  • GC01P210281
  • GC01P209612
  • GC01P211291
  • GC01P213224
  • GC01P183899

Summaries for RPS6KC1 Gene

Entrez Gene Summary for RPS6KC1 Gene

  • Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]

GeneCards Summary for RPS6KC1 Gene

RPS6KC1 (Ribosomal Protein S6 Kinase C1) is a Protein Coding gene. Diseases associated with RPS6KC1 include Charcot-Marie-Tooth Disease, Axonal, Type 2N and Periventricular Leukomalacia. Among its related pathways are CNTF Signaling and Nanog in Mammalian ESC Pluripotency. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein serine/threonine kinase activity. An important paralog of this gene is RPS6KL1.

UniProtKB/Swiss-Prot Summary for RPS6KC1 Gene

  • May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell (PubMed:12077123). Plays a role in the recruitment of PRDX3 to early endosomes (PubMed:15750338).

Gene Wiki entry for RPS6KC1 Gene

Additional gene information for RPS6KC1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RPS6KC1 Gene

Genomics for RPS6KC1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for RPS6KC1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J213050 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 639.5 +0.5 489 3.1 RNF2 ARHGAP35 ZNF629 PRDM10 SIX5 LEF1 IKZF1 POLR2A JUND LARP7 RPS6KC1 ANGEL2 PPP2R5A RF00017-473 PROX1
GH01J213049 Enhancer 0.8 Ensembl 600.7 -1.9 -1932 0.6 ZNF512 LEF1 JUND DDX20 KAT8 BRD9 ZNF24 DPF2 HDAC1 GATAD2B RPS6KC1 ANGEL2 piR-30465-003
GH01J213079 Promoter 0.3 EPDnew 611.8 +28.6 28569 0.1 RPS6KC1 RF00994-084 RF00017-473 PROX1
GH01J213260 Enhancer 0.9 Ensembl ENCODE 38.6 +209.4 209368 1.2 JUND PKNOX1 DPF2 HDAC1 SOX6 GATAD2B EP300 HMBOX1 FOXK2 HDAC2 NONHSAG004256.2 RPS6KC1 piR-48553-029 PROX1
GH01J212977 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 20.9 -71.1 -71085 5.6 SP1 CTCF ZNF512 RFX1 ZNF692 POLR2A FOXA1 PHF21A RELA REST HSALNG0010417 RPS6KC1 VASH2 BATF3 ANGEL2 TATDN3 lnc-VASH2-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RPS6KC1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RPS6KC1

Top Transcription factor binding sites by QIAGEN in the RPS6KC1 gene promoter:
  • c-Ets-1
  • Egr-4
  • Elk-1
  • LCR-F1
  • MEF-2
  • MEF-2A
  • NRF-2
  • Olf-1

Genomic Locations for RPS6KC1 Gene

Genomic Locations for RPS6KC1 Gene
chr1:213,051,233-213,378,753
(GRCh38/hg38)
Size:
327,521 bases
Orientation:
Plus strand
chr1:213,224,588-213,448,116
(GRCh37/hg19)
Size:
223,529 bases
Orientation:
Plus strand

Genomic View for RPS6KC1 Gene

Genes around RPS6KC1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RPS6KC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RPS6KC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPS6KC1 Gene

Proteins for RPS6KC1 Gene

  • Protein details for RPS6KC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96S38-KS6C1_HUMAN
    Recommended name:
    Ribosomal protein S6 kinase delta-1
    Protein Accession:
    Q96S38
    Secondary Accessions:
    • B1APS8
    • B3KVM4
    • D3DTA4
    • Q8TDD3
    • Q9NSF4
    • Q9UL66

    Protein attributes for RPS6KC1 Gene

    Size:
    1066 amino acids
    Molecular mass:
    118682 Da
    Quaternary structure:
    • Interacts with SPHK1 and phosphatidylinositol 3-phosphate (PubMed:12077123). Interacts (via PX domain) with PRDX3 (PubMed:15750338).
    SequenceCaution:
    • Sequence=CAB92850.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for RPS6KC1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RPS6KC1 Gene

Post-translational modifications for RPS6KC1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for RPS6KC1 Gene

Domains & Families for RPS6KC1 Gene

Gene Families for RPS6KC1 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins

Protein Domains for RPS6KC1 Gene

Suggested Antigen Peptide Sequences for RPS6KC1 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ61257, highly similar to Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (B4DHE1_HUMAN)
  • SPHK1-binding protein (KS6C1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q96S38

UniProtKB/Swiss-Prot:

KS6C1_HUMAN :
  • The PX domain is essential for its localization to the early endosomes.
  • Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.
Domain:
  • The PX domain is essential for its localization to the early endosomes.
  • The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site.
Family:
  • Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.
genes like me logo Genes that share domains with RPS6KC1: view

Function for RPS6KC1 Gene

Molecular function for RPS6KC1 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell (PubMed:12077123). Plays a role in the recruitment of PRDX3 to early endosomes (PubMed:15750338).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.1;.
GENATLAS Biochemistry:
ribosomal protein S6 kinase,polypeptide 1,expressed highly in testis,skeletal muscle,brain and pancreas,not involved in vivo in the phosphorylation of RPS6,mediating protein synthesis initiation and elongation induced by hormones or growth factors,maybe playing an essentilal regulatory role in protein synthesis during cell proliferation

Enzyme Numbers (IUBMB) for RPS6KC1 Gene

Phenotypes From GWAS Catalog for RPS6KC1 Gene

Gene Ontology (GO) - Molecular Function for RPS6KC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0004672 protein kinase activity IEA --
GO:0004674 protein serine/threonine kinase activity TAS,IEA --
GO:0005515 protein binding IPI 15750338
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with RPS6KC1: view
genes like me logo Genes that share phenotypes with RPS6KC1: view

Animal Models for RPS6KC1 Gene

MGI Knock Outs for RPS6KC1:
  • Rps6kc1 Rps6kc1<tm1b(EUCOMM)Wtsi>

Animal Model Products

  • Taconic Biosciences Mouse Models for RPS6KC1

CRISPR Products

miRNA for RPS6KC1 Gene

miRTarBase miRNAs that target RPS6KC1

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RPS6KC1

Clone Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RPS6KC1 Gene

Localization for RPS6KC1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RPS6KC1 Gene

Cytoplasm. Membrane. Early endosome.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RPS6KC1 gene
Compartment Confidence
endosome 5
cytosol 4
nucleus 2
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endosomes (4)
  • Lysosomes (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RPS6KC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005768 endosome IEA --
GO:0005769 early endosome IBA,IDA 15750338
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with RPS6KC1: view

Pathways & Interactions for RPS6KC1 Gene

PathCards logo

SuperPathways for RPS6KC1 Gene

SuperPathway Contained pathways
1 Nanog in Mammalian ESC Pluripotency
.59
2 CNTF Signaling
.50
genes like me logo Genes that share pathways with RPS6KC1: view

Pathways by source for RPS6KC1 Gene

2 Qiagen pathways for RPS6KC1 Gene
  • 14-3-3 Induced Intracellular Signaling
  • FLT3 Signaling

Gene Ontology (GO) - Biological Process for RPS6KC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006468 protein phosphorylation IEA --
GO:0007165 signal transduction TAS 10552933
GO:0016310 phosphorylation IEA --
genes like me logo Genes that share ontologies with RPS6KC1: view

No data available for SIGNOR curated interactions for RPS6KC1 Gene

Drugs & Compounds for RPS6KC1 Gene

No Compound Related Data Available

Transcripts for RPS6KC1 Gene

mRNA/cDNA for RPS6KC1 Gene

31 REFSEQ mRNAs :
16 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RPS6KC1

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RPS6KC1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b
SP1: - -
SP2: - - -
SP3: - -
SP4:

Relevant External Links for RPS6KC1 Gene

GeneLoc Exon Structure for
RPS6KC1

Expression for RPS6KC1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RPS6KC1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for RPS6KC1 Gene

This gene is overexpressed in Adipocyte (57.5) and Monocytes (9.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RPS6KC1 Gene



Protein tissue co-expression partners for RPS6KC1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RPS6KC1

SOURCE GeneReport for Unigene cluster for RPS6KC1 Gene:

Hs.591416

mRNA Expression by UniProt/SwissProt for RPS6KC1 Gene:

Q96S38-KS6C1_HUMAN
Tissue specificity: Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.

Evidence on tissue expression from TISSUES for RPS6KC1 Gene

  • Nervous system(4.8)
  • Heart(4.6)
  • Liver(4.2)
genes like me logo Genes that share expression patterns with RPS6KC1: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for RPS6KC1 Gene

Orthologs for RPS6KC1 Gene

This gene was present in the common ancestor of animals.

Orthologs for RPS6KC1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia RPS6KC1 30 31
  • 99.81 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia RPS6KC1 30 31
  • 92.75 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia RPS6KC1 30 31
  • 90.27 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Rps6kc1 30
  • 80.52 (n)
Oppossum
(Monodelphis domestica)
Mammalia RPS6KC1 31
  • 80 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Rps6kc1 30 17 31
  • 79.64 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia RPS6KC1 31
  • 75 (a)
OneToOne
Chicken
(Gallus gallus)
Aves RPS6KC1 30 31
  • 74.75 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia RPS6KC1 31
  • 68 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia rps6kc1 30
  • 65.01 (n)
Zebrafish
(Danio rerio)
Actinopterygii RPS6KC1 31
  • 48 (a)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta CG7156 30 31
  • 44.87 (n)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001909 30
  • 41.86 (n)
Worm
(Caenorhabditis elegans)
Secernentea rskd-1 31
  • 20 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 28 (a)
OneToMany
Species where no ortholog for RPS6KC1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for RPS6KC1 Gene

ENSEMBL:
Gene Tree for RPS6KC1 (if available)
TreeFam:
Gene Tree for RPS6KC1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for RPS6KC1: view image

Paralogs for RPS6KC1 Gene

Paralogs for RPS6KC1 Gene

(4) SIMAP similar genes for RPS6KC1 Gene using alignment to 3 proteins:

  • KS6C1_HUMAN
  • B4DHE1_HUMAN
  • F5H7T0_HUMAN
genes like me logo Genes that share paralogs with RPS6KC1: view

Variants for RPS6KC1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RPS6KC1 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
718847 Benign: not provided 213,242,221(+) A/G NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
726712 Benign: not provided 213,241,158(+) C/G MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
786996 Benign: not provided 213,241,112(+) G/C MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
791830 Benign: not provided 213,051,518(+) C/T INTRON_VARIANT
rs193921071 Uncertain Significance: Malignant tumor of prostate 213,272,596(+) T/C MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for RPS6KC1 Gene

Structural Variations from Database of Genomic Variants (DGV) for RPS6KC1 Gene

Variant ID Type Subtype PubMed ID
dgv573n100 CNV gain 25217958
esv1004277 CNV gain 20482838
esv2666633 CNV deletion 23128226
esv2671923 CNV deletion 23128226
esv2675698 CNV deletion 23128226
esv275574 CNV gain+loss 21479260
esv28931 CNV loss 19812545
esv3546288 CNV deletion 23714750
esv3588764 CNV loss 21293372
esv3588765 CNV loss 21293372
nsv4476 CNV insertion 18451855
nsv508692 CNV deletion 20534489
nsv508693 CNV deletion 20534489
nsv549178 CNV loss 21841781
nsv826598 CNV loss 20364138

Variation tolerance for RPS6KC1 Gene

Residual Variation Intolerance Score: 20.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.32; 62.98% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RPS6KC1 Gene

Human Gene Mutation Database (HGMD)
RPS6KC1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
RPS6KC1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPS6KC1 Gene

Disorders for RPS6KC1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for RPS6KC1 Gene - From: DISEASES and GeneCards

- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with RPS6KC1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RPS6KC1 Gene

Publications for RPS6KC1 Gene

  1. Cloning, characterization, and chromosome mapping of RPS6KC1, a novel putative member of the ribosome protein S6 kinase family, to chromosome 12q12-q13.1. (PMID: 10552933) Zhang H … Zhao S (Genomics 1999) 2 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4
  3. RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains. (PMID: 15750338) Liu L … Yu L (Molecules and cells 2005) 3 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4

Products for RPS6KC1 Gene

Sources for RPS6KC1 Gene