Aliases for RPS6KC1 Gene
External Ids for RPS6KC1 Gene
Previous GeneCards Identifiers for RPS6KC1 Gene
Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]
GeneCards Summary for RPS6KC1 Gene
RPS6KC1 (Ribosomal Protein S6 Kinase C1) is a Protein Coding gene. Diseases associated with RPS6KC1 include Periventricular Leukomalacia. Among its related pathways are CNTF Signaling and Nanog in Mammalian ESC Pluripotency. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein serine/threonine kinase activity. An important paralog of this gene is RPS6KL1.
UniProtKB/Swiss-Prot Summary for RPS6KC1 Gene
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell (PubMed:12077123). Plays a role in the recruitment of PRDX3 to early endosomes (PubMed:15750338).