Aliases for RPS18 Gene
External Ids for RPS18 Gene
Previous HGNC Symbols for RPS18 Gene
Previous GeneCards Identifiers for RPS18 Gene
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
GeneCards Summary for RPS18 Gene
RPS18 (Ribosomal Protein S18) is a Protein Coding gene. Diseases associated with RPS18 include Chicken Egg Allergy and Retinitis Pigmentosa 49. Among its related pathways are Viral mRNA Translation and Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding.
UniProtKB/Swiss-Prot Summary for RPS18 Gene
Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.