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RPRD1B (Regulation Of Nuclear Pre-MRNA Domain Containing 1B) is a Protein Coding gene. Diseases associated with RPRD1B include Retroperitoneal Leiomyosarcoma and Polyneuropathy Due To Drug. Among its related pathways are Gene Expression and HIV Transcription Elongation. Gene Ontology (GO) annotations related to this gene include RNA polymerase II complex binding. An important paralog of this gene is RPRD1A.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000993 | RNA polymerase II complex binding | IBA,IDA | 22264791 |
GO:0005515 | protein binding | IPI | 22264791 |
GO:0042802 | identical protein binding | IPI | 24997600 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,IDA | 22264791 |
GO:0005654 | nucleoplasm | TAS | -- |
GO:0016591 | RNA polymerase II, holoenzyme | IBA,IDA | 22231121 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Gene Expression |
.48
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2 | HIV Transcription Elongation |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008284 | positive regulation of cell proliferation | IDA | 22264791 |
GO:0010564 | regulation of cell cycle process | IDA | 22264791 |
GO:0031124 | mRNA 3'-end processing | IBA | 21873635 |
GO:0042795 | snRNA transcription by RNA polymerase II | TAS | -- |
GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA | 22264791 |
ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||
SP2: | - | - | - | - | |||||||||||||||||||||||||||||||
SP3: | - | - | |||||||||||||||||||||||||||||||||
SP4: | - | - | |||||||||||||||||||||||||||||||||
SP5: | - | ||||||||||||||||||||||||||||||||||
SP6: | |||||||||||||||||||||||||||||||||||
SP7: |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RPRD1B 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RPRD1B 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RPRD1B 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Rprd1b 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Rprd1b 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | RPRD1B 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Chicken (Gallus gallus) |
Aves | RPRD1B 30 |
|
||
CREPT 31 |
|
OneToOne | |||
Lizard (Anolis carolinensis) |
Reptilia | RPRD1B 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rprd1a 30 |
|
||
Str.4805 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.29308 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | rprd1b 30 31 |
|
OneToOne | |
wufb23h08 30 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005331 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG9018 30 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | cids-1 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RTT103 31 33 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.4640 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv4308n100 | CNV | gain | 25217958 |
esv2670839 | CNV | deletion | 23128226 |
esv2763659 | CNV | gain | 21179565 |
esv3645771 | CNV | loss | 21293372 |
nsv1057334 | CNV | loss | 25217958 |
nsv585963 | CNV | gain | 21841781 |
nsv833971 | CNV | gain | 17160897 |
nsv833972 | CNV | loss | 17160897 |
Disorder | Aliases | PubMed IDs |
---|---|---|
retroperitoneal leiomyosarcoma |
|
|
polyneuropathy due to drug |
|
|
inflammatory and toxic neuropathy |
|
|
gnathomiasis |
|
|
retroperitoneal sarcoma |
|
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