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Aliases for RPRD1B Gene
Aliases for RPRD1B Gene
External Ids for RPRD1B Gene
- HGNC: 16209
- Entrez Gene: 58490
- Ensembl: ENSG00000101413
- OMIM: 614694
- UniProtKB: Q9NQG5
Previous HGNC Symbols for RPRD1B Gene
- C20orf77
Previous GeneCards Identifiers for RPRD1B Gene
- GC20P036096
- GC20P036662
- GC20P033397
Summaries for RPRD1B Gene
GeneCards Summary for RPRD1B Gene
RPRD1B (Regulation Of Nuclear Pre-MRNA Domain Containing 1B) is a Protein Coding gene. Diseases associated with RPRD1B include Retroperitoneal Leiomyosarcoma and Polyneuropathy Due To Drug. Among its related pathways are Gene Expression and HIV Transcription Elongation. Gene Ontology (GO) annotations related to this gene include RNA polymerase II complex binding. An important paralog of this gene is RPRD1A.
UniProtKB/Swiss-Prot Summary for RPRD1B Gene
-
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
Additional gene information for RPRD1B Gene
- HGNC(16209)
- Entrez Gene(58490)
- Ensembl(ENSG00000101413)
- OMIM(614694)
- UniProtKB(Q9NQG5)
- Open Targets Platform(ENSG00000101413)
- Monarch Initiative
- Search for RPRD1B at DataMed
- Search for RPRD1B at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RPRD1B Gene
Genomics for RPRD1B Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RPRD1B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RPRD1B on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RPRD1B
- Top Transcription factor binding sites by QIAGEN in the RPRD1B gene promoter:
-
- CUTL1
- E2F
- E2F-1
- GR
- GR-alpha
- GR-beta
- Sox9
Genomic Locations for RPRD1B Gene
Genomic Locations for RPRD1B Gene
- chr20:38,033,462-38,127,780
- (GRCh38/hg38)
- Size:
- 94,319 bases
- Orientation:
- Plus strand
- chr20:36,661,948-36,720,768
- (GRCh37/hg19)
- Size:
- 58,821 bases
- Orientation:
- Plus strand
Genomic View for RPRD1B Gene
Genes around RPRD1B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 20q11.23 by HGNC
- 20q11.23 by Entrez Gene
- 20q11.23 by Ensembl
RPRD1B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RPRD1B Gene
Proteins for RPRD1B Gene
-
Protein details for RPRD1B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NQG5-RPR1B_HUMAN
- Recommended name:
- Regulation of nuclear pre-mRNA domain-containing protein 1B
- Protein Accession:
- Q9NQG5
- Q1WDE7
- Q6PKF4
Protein attributes for RPRD1B Gene
- Size:
- 326 amino acids
- Molecular mass:
- 36900 Da
- Quaternary structure:
-
- Homodimer (PubMed:24997600). May form a heterodimer with RPRD1A (PubMed:24997600). Associates with RPAP2 (PubMed:24997600). Associates with the RNA polymerase II complex (PubMed:22231121, PubMed:24399136, PubMed:24997600).
- SequenceCaution:
-
- Sequence=AAH01696.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
Protein Expression for RPRD1B Gene
Post-translational modifications for RPRD1B Gene
Other Protein References for RPRD1B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- GeneTex Anti-RPRD1B antibody
-
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-
Abcam antibodies for RPRD1B
- Invitrogen Antibodies for RPRD1B (AFLGC-RPRD1B)
-
Biorbyt antibodies for RPRD1B
-
Boster Bio Antibodies for RPRD1B
- Sino Biological Antibodies for RPRD1B
Protein Products
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- Sino Biological Cell Lysates for RPRD1B
- Sino Biological Recombinant Proteins for RPRD1B
- ProSpec Recombinant Proteins for RPRD1B
- antibodies-online: Show 7 available RPRD1B Proteins ranked by validation data
- Compare Top RPRD1B Proteins
-
Quality Products:
-
Abcam proteins for RPRD1B
No data available for DME Specific Peptides for RPRD1B Gene
Domains & Families for RPRD1B Gene
Gene Families for RPRD1B Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for RPRD1B Gene
- InterPro:
- Blocks:
-
- Regulation of nuclear pre-mRNA protein
- ProtoNet:
Suggested Antigen Peptide Sequences for RPRD1B Gene
- GenScript: Design optimal peptide antigens:
-
- Cell cycle-related and expression-elevated protein in tumor (RPR1B_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9NQG5- Family:
-
- Belongs to the UPF0400 (RTT103) family.
Function for RPRD1B Gene
Molecular function for RPRD1B Gene
- UniProtKB/Swiss-Prot Function:
- Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
Phenotypes From GWAS Catalog for RPRD1B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000993 | RNA polymerase II complex binding | IBA,IDA | 22264791 |
| GO:0005515 | protein binding | IPI | 22264791 |
| GO:0042802 | identical protein binding | IPI | 24997600 |
Phenotypes for RPRD1B Gene
- MGI mutant phenotypes for RPRD1B:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RPRD1B:
Animal Models for RPRD1B Gene
- MGI Knock Outs for RPRD1B:
-
- Rprd1b Rprd1b<tm1a(EUCOMM)Hmgu>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RPRD1B - Select products 50% OFF >
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-
Santa Cruz Biotechnology (SCBT) CRISPR for RPRD1B
miRNA for RPRD1B Gene
- miRTarBase miRNAs that target RPRD1B
-
- hsa-miR-130b-3p (MIRT020154)
- hsa-miR-124-3p (MIRT022922)
- hsa-miR-103a-3p (MIRT027086)
- hsa-miR-30a-5p (MIRT028504)
- hsa-miR-16-5p (MIRT031629)
- hsa-miR-33a-5p (MIRT049853)
- mmu-miR-129-5p (MIRT593705)
- mmu-miR-218-5p (MIRT594267)
- hsa-miR-15a-5p (MIRT737945)
- hsa-miR-15b-5p (MIRT737965)
- hsa-miR-195-5p (MIRT738634)
- hsa-miR-3944-5p (MIRT743177)
- hsa-miR-424-5p (MIRT743309)
- hsa-miR-497-5p (MIRT749290)
- hsa-miR-504-3p (MIRT749558)
- hsa-miR-545-3p (MIRT750458)
- hsa-miR-6838-5p (MIRT757292)
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for RPRD1B - Select products 50% OFF >
- * RPRD1B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for RPRD1B
- Addgene plasmids for RPRD1B
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RPRD1B Gene
Localization for RPRD1B Gene
Subcellular locations from UniProtKB/Swiss-Prot for RPRD1B Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 22264791 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0016591 | RNA polymerase II, holoenzyme | IBA,IDA | 22231121 |
Pathways & Interactions for RPRD1B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
| 2 | HIV Transcription Elongation | ||
Pathways by source for RPRD1B Gene
2 Reactome pathways for RPRD1B Gene
Interacting Proteins for RPRD1B Gene
Selected Interacting proteins:
Q9NQG5-RPR1B_HUMAN
ENSP00000362532
for RPRD1B Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for RPRD1B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008284 | positive regulation of cell proliferation | IDA | 22264791 |
| GO:0010564 | regulation of cell cycle process | IDA | 22264791 |
| GO:0031124 | mRNA 3'-end processing | IBA | 21873635 |
| GO:0042795 | snRNA transcription by RNA polymerase II | TAS | -- |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA | 22264791 |
No data available for SIGNOR curated interactions for RPRD1B Gene
Transcripts for RPRD1B Gene
mRNA/cDNA for RPRD1B Gene
- 1 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000373433 3672 nts (view in UCSC)
- ENST00000449186 591 nts (view in UCSC)
- ENST00000462548 2436 nts (view in UCSC)
- ENST00000471511 571 nts (view in UCSC)
- ENST00000484683 554 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RPRD1B - Select products 50% OFF >
- * RPRD1B CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RPRD1B
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-
Santa Cruz Biotechnology (SCBT) CRISPR for RPRD1B
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for RPRD1B - Select products 50% OFF >
- * RPRD1B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for RPRD1B
- Addgene plasmids for RPRD1B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RPRD1B
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||
| SP7: |
Relevant External Links for RPRD1B Gene
- GeneLoc Exon Structure for
- RPRD1B
Expression for RPRD1B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Skeletal Muscle (Muscoskeletal System)
- Eye (Sensory Organs)
mRNA differential expression in normal tissues according to GTEx for RPRD1B Gene
This gene is overexpressed in Liver (x6.1).
This gene is overexpressed in Peripheral blood mononuclear cells (8.7) and Lymph node (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RPRD1B Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RPRD1B
SOURCE GeneReport for Unigene cluster for RPRD1B Gene:
Hs.278839mRNA Expression by UniProt/SwissProt for RPRD1B Gene:
Q9NQG5-RPR1B_HUMAN
Tissue specificity:
Preferentially expressed in a range of tumor tissues including colon, lung, liver, breast, prostate, stomach, uterine endometrium and cervical cancers with higher levels in tumors than in adjacent non-tumor tissue (at protein level).
Evidence on tissue expression from TISSUES for RPRD1B Gene
- Nervous system(4.8)
- Liver(4.5)
- Skin(2.4)
- Muscle(2.2)
- Heart(2.2)
- Blood(2.2)
- Intestine(2)
Primer Products
-
OriGene qPCR primer pairs for RPRD1B
-
OriGene qPCR primer pairs and template standards for RPRD1B
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for RPRD1B Gene
Orthologs for RPRD1B Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RPRD1B 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RPRD1B 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RPRD1B 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rprd1b 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Rprd1b 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | RPRD1B 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Chicken (Gallus gallus) |
Aves | RPRD1B 30 |
|
||
| CREPT 31 |
|
OneToOne | |||
| Lizard (Anolis carolinensis) |
Reptilia | RPRD1B 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rprd1a 30 |
|
||
| Str.4805 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.29308 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rprd1b 30 31 |
|
OneToOne | |
| wufb23h08 30 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005331 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG9018 30 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | cids-1 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RTT103 31 33 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.4640 31 |
|
OneToMany |
- Species where no ortholog for RPRD1B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for RPRD1B Gene
- ENSEMBL:
- Gene Tree for RPRD1B (if available)
- TreeFam:
- Gene Tree for RPRD1B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RPRD1B: view image
Paralogs for RPRD1B Gene
Variants for RPRD1B Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4308n100 | CNV | gain | 25217958 |
| esv2670839 | CNV | deletion | 23128226 |
| esv2763659 | CNV | gain | 21179565 |
| esv3645771 | CNV | loss | 21293372 |
| nsv1057334 | CNV | loss | 25217958 |
| nsv585963 | CNV | gain | 21841781 |
| nsv833971 | CNV | gain | 17160897 |
| nsv833972 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
24.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.89;
18.58% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RPRD1B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RPRD1B
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RPRD1B Gene
Disorders for RPRD1B Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| retroperitoneal leiomyosarcoma |
|
|
| polyneuropathy due to drug |
|
|
| inflammatory and toxic neuropathy |
|
|
| gnathomiasis |
|
|
| retroperitoneal sarcoma |
|
|
Search RPRD1B in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RPRD1B
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for RPRD1B Gene
Publications for RPRD1B Gene
- Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B. (PMID: 22231121) Ni Z … Greenblatt JF (Transcription 2011) 2 3 4
- RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. (PMID: 24997600) Ni Z … Greenblatt JF (Nature structural & molecular biology 2014) 3 4
- CREPT accelerates tumorigenesis by regulating the transcription of cell-cycle-related genes. (PMID: 22264791) Lu D … Chang Z (Cancer cell 2012) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for RPRD1B Gene
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- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RPRD1B
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RPRD1B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RPRD1B
- Boster Bio Antibodies for RPRD1B
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for RPRD1B
Sources for RPRD1B Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB