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Aliases for RPPH1-3P Gene

Subcategory (RNA class) for RPPH1-3P Gene

lncRNA

Aliases for RPPH1-3P Gene

  • Ribonuclease P RNA Component H1, 3 Pseudogene 2 3 5

External Ids for RPPH1-3P Gene

ORGUL Members for RPPH1-3P Gene

Previous GeneCards Identifiers for RPPH1-3P Gene

  • GC04M157910

Summaries for RPPH1-3P Gene

GeneCards Summary for RPPH1-3P Gene

RPPH1-3P (Ribonuclease P RNA Component H1, 3 Pseudogene) is a Pseudogene, and is affiliated with the lncRNA class.

fRNAdb sequence ontologies for RPPH1-3P Gene

  • RNase_P_RNA: The RNA component of Ribonuclease P (RNase P), a ubiquitous endoribonuclease, found in archaea, bacteria and eukarya as well as chloroplasts and mitochondria. Its best characterised activity is the generation of mature 5 prime ends of tRNAs by cleaving the 5 prime leader elements of precursor-tRNAs. Cellular RNase Ps are ribonucleoproteins. RNA from bacterial RNase Ps retains its catalytic activity in the absence of the protein subunit, i.e. it is a ribozyme. Isolated eukaryotic and archaeal RNase P RNA has not been shown to retain its catalytic function, but is still essential for the catalytic activity of the holoenzyme. Although the archaeal and eukaryotic holoenzymes have a much greater protein content than the bacterial ones, the RNA cores from all the three lineages are homologous. Helices corresponding to P1, P2, P3, P4, and P10/11 are common to all cellular RNase P RNAs. Yet, there is considerable sequence variation, particularly among the eukaryotic RNAs.

View fRNAdb secondary structures for RPPH1-3P

Additional gene information for RPPH1-3P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RPPH1-3P Gene

Genomics for RPPH1-3P Gene

GeneHancer (GH) Regulatory Elements for RPPH1-3P Gene

Promoters and enhancers for RPPH1-3P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I156998 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.4 -12.8 -12833 1.9 PKNOX1 NFIB JUN ZBTB40 TEAD3 POLR2A FOSL2 ZNF444 FOS ZNF362 PDGFC ENSG00000250622 GLRB RPPH1-3P GC04P157065
GH04I157003 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.4 -17.7 -17696 2.3 ELF3 ZBTB6 RXRA JUN HLF MAX CEBPB ATF2 YY1 JUND ENSG00000250622 PDGFC GLRB RPPH1-3P GC04P157065
GH04I157014 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.3 -28.7 -28717 1.2 SP1 SRF JUND USF1 FOS RUNX3 GLRB RPPH1-3P GC04P157065
GH04I156982 Enhancer 0.3 dbSUPER 0.8 +3.8 3838 1 CTCF RPPH1-3P ENSG00000250622
GH04I156975 Enhancer 0.6 ENCODE dbSUPER 0.4 +9.8 9808 3.3 JUND POLR2A FOS ENSG00000250622 RPPH1-3P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RPPH1-3P on UCSC Golden Path with GeneCards custom track

Genomic Locations for RPPH1-3P Gene

Genomic Locations for RPPH1-3P Gene
chr4:156,986,372-156,986,693
(GRCh38/hg38)
Size:
322 bases
Orientation:
Minus strand
chr4:157,907,524-157,907,845
(GRCh37/hg19)

Genomic View for RPPH1-3P Gene

Genes around RPPH1-3P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RPPH1-3P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RPPH1-3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPPH1-3P Gene

ORGUL Member Location for RPPH1-3P Gene

ORGUL Member Location for RPPH1-3P gene

Proteins for RPPH1-3P Gene

Post-translational modifications for RPPH1-3P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RPPH1-3P Gene

Domains & Families for RPPH1-3P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RPPH1-3P Gene

Function for RPPH1-3P Gene

Phenotypes From GWAS Catalog for RPPH1-3P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RPPH1-3P Gene

Localization for RPPH1-3P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RPPH1-3P Gene

Pathways & Interactions for RPPH1-3P Gene

SuperPathways for RPPH1-3P Gene

No Data Available

Interacting Proteins for RPPH1-3P Gene

Gene Ontology (GO) - Biological Process for RPPH1-3P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RPPH1-3P Gene

Drugs & Compounds for RPPH1-3P Gene

No Compound Related Data Available

Transcripts for RPPH1-3P Gene

fRNAdb Secondary structures for RPPH1-3P Gene

  • NONHSAG039199

mRNA/cDNA for RPPH1-3P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RPPH1-3P Gene

No ASD Table

Relevant External Links for RPPH1-3P Gene

GeneLoc Exon Structure for
RPPH1-3P
ECgene alternative splicing isoforms for
RPPH1-3P

Expression for RPPH1-3P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RPPH1-3P Gene

genes like me logo Genes that share expression patterns with RPPH1-3P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RPPH1-3P Gene

Orthologs for RPPH1-3P Gene

This gene was present in the common ancestor of chordates.

Orthologs for RPPH1-3P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RNaseP_nuc 34
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25694 34
  • 57 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RNaseP_nuc 34
  • 56 (a)
OneToMany
dog
(Canis familiaris)
Mammalia RNaseP_nuc 34 34
  • 51 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia RNaseP_nuc 34
  • 51 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RNaseP_nuc 34 34 34
  • 44 (a)
OneToMany
chicken
(Gallus gallus)
Aves RNaseP_nuc 34
  • 46 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia RNaseP_nuc 34 34
  • 41 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii RNaseP_nuc 34 34 34 34
  • 46 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea RNaseP_nuc 34 34
  • 41 (a)
ManyToMany
Species where no ortholog for RPPH1-3P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RPPH1-3P Gene

ENSEMBL:
Gene Tree for RPPH1-3P (if available)
TreeFam:
Gene Tree for RPPH1-3P (if available)

Paralogs for RPPH1-3P Gene

No data available for Paralogs for RPPH1-3P Gene

Variants for RPPH1-3P Gene

Additional Variant Information for RPPH1-3P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RPPH1-3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RPPH1-3P Gene

Disorders for RPPH1-3P Gene

No disorders were found for RPPH1-3P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RPPH1-3P Gene

Publications for RPPH1-3P Gene

  1. Structural implications of novel diversity in eucaryal RNase P RNA. (PMID: 15811915) Marquez SM … Pace NR (RNA (New York, N.Y.) 2005) 1
  2. Eukaryotic ribonuclease P: a plurality of ribonucleoprotein enzymes. (PMID: 12045094) Xiao S … Engelke DR (Annual review of biochemistry 2002) 1
  3. Phylogenetic-comparative analysis of the eukaryal ribonuclease P RNA. (PMID: 11142387) Frank DN … Pace NR (RNA (New York, N.Y.) 2000) 1
  4. The Ribonuclease P Database. (PMID: 9847214) Brown JW (Nucleic acids research 1999) 1
  5. Ribonuclease P: unity and diversity in a tRNA processing ribozyme. (PMID: 9759486) Frank DN … Pace NR (Annual review of biochemistry 1998) 1

Products for RPPH1-3P Gene

Sources for RPPH1-3P Gene

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