Aliases for RPP25 Gene
External Ids for RPP25 Gene
Previous GeneCards Identifiers for RPP25 Gene
GeneCards Summary for RPP25 Gene
RPP25 (Ribonuclease P And MRP Subunit P25) is a Protein Coding gene. Diseases associated with RPP25 include Chromosome 15Q24 Deletion Syndrome and Diffuse Scleroderma. Among its related pathways are rRNA processing in the nucleus and cytosol and tRNA processing. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and ribonuclease P activity. An important paralog of this gene is RPP25L.
UniProtKB/Swiss-Prot Summary for RPP25 Gene
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:12003489, PubMed:16723659, PubMed:30454648). Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).