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Aliases for RPN2 Gene

Aliases for RPN2 Gene

  • Ribophorin II 2 3 4 5
  • Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 63 KDa Subunit 3 4
  • Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 2 3 4
  • Oligosaccharyltransferase Complex Subunit (Non-Catalytic) 2 3
  • Ribophorin-2 3 4
  • RIBIIR 3 4
  • RPN-II 3 4
  • EC 2.4.1.119 56
  • RPNII 3
  • SWP1 3

External Ids for RPN2 Gene

Previous GeneCards Identifiers for RPN2 Gene

  • GC20P035535
  • GC20P036445
  • GC20P036492
  • GC20P035240
  • GC20P035806
  • GC20P032542

Summaries for RPN2 Gene

Entrez Gene Summary for RPN2 Gene

  • This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

GeneCards Summary for RPN2 Gene

RPN2 (Ribophorin II) is a Protein Coding gene. Diseases associated with RPN2 include Encephalitozoonosis and Microsporidiosis. Among its related pathways are Transport to the Golgi and subsequent modification and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include ribosome binding and dolichyl-diphosphooligosaccharide-protein glycotransferase activity.

UniProtKB/Swiss-Prot for RPN2 Gene

  • Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

Gene Wiki entry for RPN2 Gene

Additional gene information for RPN2 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RPN2 Gene

Genomics for RPN2 Gene

GeneHancer (GH) Regulatory Elements for RPN2 Gene

Promoters and enhancers for RPN2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J037177 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 613 +0.9 891 3.4 ZNF652 SP1 ZFX ELF3 CTCF MNT SIX5 ZNF148 NKRF POLR2A MROH8 RPN2 TTI1 RBL1 DSN1 AAR2 CTNNBL1 DLGAP4-AS1
GH20J038139 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 21.3 +977.6 977580 33.6 ZNF652 ZFX CC2D1A ELF3 CTCF ZKSCAN8 MNT CBFA2T2 ZNF148 POLR2A TGM2 RALGAPB ACTR5 RN7SKP173 SNHG17 TTI1 SNORA71A SNORA71C DHX35 RPN2
GH20J036854 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE dbSUPER 21.1 -319.3 -319254 11.7 ZNF652 CC2D1A ZFX CTCF ELF3 MNT ZNF148 NKRF POLR2A MLLT1 RBL1 AAR2 RPN2 DSN1 SOGA1 NDRG3 DLGAP4-AS1 MANBAL GC20P036795
GH20J037411 Enhancer 1.3 FANTOM5 ENCODE dbSUPER 22.9 +233.8 233767 2 CDC5L IKZF1 MCM2 ZNF548 PRDM1 ZNF24 ZSCAN4 POLR2A FOXK2 MNT RBL1 DSN1 RPN2 NNAT CTNNBL1 VSTM2L TLDC2 TGIF2 DLGAP4-AS1 SOGA1
GH20J037516 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.4 +344.4 344416 13.6 ZNF652 SP1 ZFX ELF3 MNT CBFA2T2 ZNF148 NKRF POLR2A CEBPG BLCAP NNAT RALGAPB RBL1 TTI1 SNHG17 SOGA1 SNORA71C RPN2 MROH8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RPN2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RPN2 gene promoter:
  • AP-1
  • AP-2alpha
  • AP-2alphaA
  • AP-2beta
  • AP-2gamma
  • c-Fos
  • c-Jun
  • CREB
  • E47
  • Hand1

Genomic Locations for RPN2 Gene

Genomic Locations for RPN2 Gene
chr20:37,178,410-37,241,623
(GRCh38/hg38)
Size:
63,214 bases
Orientation:
Plus strand
chr20:35,806,813-35,870,026
(GRCh37/hg19)
Size:
63,214 bases
Orientation:
Plus strand

Genomic View for RPN2 Gene

Genes around RPN2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RPN2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RPN2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RPN2 Gene

Proteins for RPN2 Gene

  • Protein details for RPN2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P04844-RPN2_HUMAN
    Recommended name:
    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
    Protein Accession:
    P04844
    Secondary Accessions:
    • Q5JYR6
    • Q6IBA5
    • Q96E21
    • Q9BUQ3
    • Q9UBE1

    Protein attributes for RPN2 Gene

    Size:
    631 amino acids
    Molecular mass:
    69284 Da
    Quaternary structure:
    • Component of the oligosaccharyltransferase (OST) complex. OST exists in two different complex forms which contain common core subunits RPN1, RPN2, OST48, OST4, DAD1 and TMEM258, either STT3A or STT3B as catalytic subunits, and form-specific accessory subunits (PubMed:23606741, PubMed:25135935). STT3A complex assembly occurs through the formation of 3 subcomplexes. Subcomplex 1 contains RPN1 and TMEM258, subcomplex 2 contains the STT3A-specific subunits STT3A, DC2/OSTC, and KCP2 as well as the core subunit OST4, and subcomplex 3 contains RPN2, DAD1, and OST48. The STT3A complex can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes (By similarity). Interacts with DDI2 (PubMed:29290612).

    Alternative splice isoforms for RPN2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RPN2 Gene

Selected DME Specific Peptides for RPN2 Gene

P04844:
  • VTFLAGNRMLAQ
  • DVERLKASLDRPFT
  • YWTQLNMFQTLKYLA
  • LLLAAVSEDS
  • PEKRPPTVVSNTFT
  • TALFVAATYKLMDHVGTEPS
  • GTEPSIKEDQVIQLMN
  • LILSPLLLLFALWIRIGA
  • NRYHVPVVVVPEGS
  • KQEIQHLFR
  • VKLEHAKS
  • KNVYKFELDTSERK

Post-translational modifications for RPN2 Gene

  • Ubiquitination at isoforms=2627 and posLast=154154
  • Glycosylation at posLast=106106
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect

Domains & Families for RPN2 Gene

Gene Families for RPN2 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Predicted secreted proteins

Protein Domains for RPN2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for RPN2 Gene

GenScript: Design optimal peptide antigens:
  • Ribophorin II (Q5JYR2_HUMAN)
  • Ribophorin II (Q5JYR3_HUMAN)
  • cDNA FLJ38924 fis, clone NT2NE2011896, highly similar to Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit (EC 2.4.1.119) (Q5JYR6_HUMAN)
  • Ribophorin-2 (RPN2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P04844

UniProtKB/Swiss-Prot:

RPN2_HUMAN :
  • Belongs to the SWP1 family.
Family:
  • Belongs to the SWP1 family.
genes like me logo Genes that share domains with RPN2: view

Function for RPN2 Gene

Molecular function for RPN2 Gene

UniProtKB/Swiss-Prot Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
GENATLAS Biochemistry:
ribophorin II,69.5kDa,component with RPN1 and DDOST of N-oligosacccharyl transferase

Enzyme Numbers (IUBMB) for RPN2 Gene

Phenotypes From GWAS Catalog for RPN2 Gene

Gene Ontology (GO) - Molecular Function for RPN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004579 contributes_to dolichyl-diphosphooligosaccharide-protein glycotransferase activity IBA,NAS 15835887
GO:0005515 protein binding IPI 24965446
GO:0043022 ribosome binding IEA --
genes like me logo Genes that share ontologies with RPN2: view
genes like me logo Genes that share phenotypes with RPN2: view

Animal Models for RPN2 Gene

MGI Knock Outs for RPN2:
  • Rpn2 Rpn2<tm1a(EUCOMM)Wtsi>

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for RPN2 - Now 50% OFF >
  • * RPN2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * RPN2 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
  • Addgene plasmids for RPN2

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RPN2 Gene

Localization for RPN2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RPN2 Gene

Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RPN2 gene
Compartment Confidence
endoplasmic reticulum 5
extracellular 2
plasma membrane 1
golgi apparatus 1
peroxisome 0
lysosome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RPN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000421 autophagosome membrane IEA --
GO:0005783 endoplasmic reticulum IEA --
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0005791 rough endoplasmic reticulum IEA --
GO:0008250 oligosaccharyltransferase complex IEA,TAS 15835887
genes like me logo Genes that share ontologies with RPN2: view

Pathways & Interactions for RPN2 Gene

genes like me logo Genes that share pathways with RPN2: view

UniProtKB/Swiss-Prot P04844-RPN2_HUMAN

  • Pathway: Protein modification; protein glycosylation.

Gene Ontology (GO) - Biological Process for RPN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006464 cellular protein modification process TAS 10660554
GO:0006486 protein glycosylation IEA --
GO:0006487 protein N-linked glycosylation IEA,IBA 21873635
GO:0007568 aging IEA --
GO:0018279 protein N-linked glycosylation via asparagine TAS,NAS --
genes like me logo Genes that share ontologies with RPN2: view

No data available for SIGNOR curated interactions for RPN2 Gene

Drugs & Compounds for RPN2 Gene

(1) Drugs for RPN2 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
asparagine Approved, Investigational Nutra 0

(1) Additional Compounds for RPN2 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Dolichyl diphosphate
37247-98-6
genes like me logo Genes that share compounds with RPN2: view

Transcripts for RPN2 Gene

Unigene Clusters for RPN2 Gene

Ribophorin II:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for RPN2 - Now 50% OFF >
  • * RPN2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * RPN2 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
  • Addgene plasmids for RPN2

Alternative Splicing Database (ASD) splice patterns (SP) for RPN2 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b ·
SP1: - - - - - - -
SP2: - - - - - - - -
SP3: - - - -
SP4: -
SP5: - - - -
SP6: - -
SP7: - - -
SP8: - -
SP9:
SP10:
SP11:
SP12:

ExUns: 17c ^ 18 ^ 19a · 19b ^ 20 ^ 21
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8: -
SP9:
SP10:
SP11:
SP12:

Relevant External Links for RPN2 Gene

GeneLoc Exon Structure for
RPN2
ECgene alternative splicing isoforms for
RPN2

Expression for RPN2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RPN2 Gene

Protein differential expression in normal tissues from HIPED for RPN2 Gene

This gene is overexpressed in Placenta (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RPN2 Gene



Protein tissue co-expression partners for RPN2 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RPN2 Gene:

RPN2

SOURCE GeneReport for Unigene cluster for RPN2 Gene:

Hs.370895

mRNA Expression by UniProt/SwissProt for RPN2 Gene:

P04844-RPN2_HUMAN
Tissue specificity: Expressed in all tissues tested.

Evidence on tissue expression from TISSUES for RPN2 Gene

  • Pancreas(4.8)
  • Liver(4.6)
  • Blood(4.4)
  • Muscle(4.4)
  • Nervous system(4.3)
  • Intestine(4.1)
  • Lung(3.8)
  • Skin(3.7)
  • Eye(3.1)
  • Kidney(2.2)
  • Thyroid gland(2.1)
  • Spleen(2)
genes like me logo Genes that share expression patterns with RPN2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for RPN2 Gene

Orthologs for RPN2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RPN2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RPN2 35 34
  • 99.26 (n)
OneToOne
dog
(Canis familiaris)
Mammalia RPN2 35 34
  • 91.8 (n)
OneToOne
cow
(Bos Taurus)
Mammalia RPN2 35 34
  • 91.34 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rpn2 34
  • 89.43 (n)
mouse
(Mus musculus)
Mammalia Rpn2 17 35 34
  • 88.38 (n)
oppossum
(Monodelphis domestica)
Mammalia RPN2 35
  • 83 (a)
OneToOne
chicken
(Gallus gallus)
Aves RPN2 35 34
  • 75.83 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RPN2 35
  • 80 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia rpn2 34
  • 69.27 (n)
Str.9570 34
African clawed frog
(Xenopus laevis)
Amphibia MGC53764 34
zebrafish
(Danio rerio)
Actinopterygii rpn2 35 34
  • 66.83 (n)
OneToOne
Dr.4217 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.1730 34
fruit fly
(Drosophila melanogaster)
Insecta OstDelta 34
  • 45.96 (n)
CG6370 35 36
  • 30 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007638 34
  • 44.55 (n)
worm
(Caenorhabditis elegans)
Secernentea ostd-1 35 34
  • 48.85 (n)
OneToOne
M01A10.3 36
  • 36 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons HAP6 34
  • 43.43 (n)
rice
(Oryza sativa)
Liliopsida Os01g0911200 34
  • 43.51 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10212 35
  • 33 (a)
OneToOne
Species where no ortholog for RPN2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RPN2 Gene

ENSEMBL:
Gene Tree for RPN2 (if available)
TreeFam:
Gene Tree for RPN2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for RPN2: view image

Paralogs for RPN2 Gene

No data available for Paralogs for RPN2 Gene

Variants for RPN2 Gene

Sequence variations from dbSNP and Humsavar for RPN2 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs376939930 likely-benign, Congenital disorder of glycosylation 37,232,290(+) C/G/T intron_variant
rs750026130 uncertain-significance, Congenital disorder of glycosylation 37,199,059(+) T/G coding_sequence_variant, intron_variant, missense_variant
rs148488636 uncertain-significance, not specified 37,184,362(+) C/T 5_prime_UTR_variant, coding_sequence_variant, missense_variant
rs727504128 uncertain-significance, not specified 37,203,945(+) C/T coding_sequence_variant, synonymous_variant
rs770535836 uncertain-significance, not specified 37,223,903(+) T/C coding_sequence_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for RPN2 Gene

Variant ID Type Subtype PubMed ID
dgv2248n106 CNV deletion 24896259
esv1174249 CNV deletion 17803354
esv2082246 CNV deletion 18987734
esv2516589 CNV deletion 19546169
esv2663037 CNV deletion 23128226
esv2722385 CNV deletion 23290073
esv3557043 CNV deletion 23714750
esv3567958 CNV loss 25503493
esv3645750 CNV gain 21293372
esv4013 CNV loss 18987735
esv8416 CNV loss 19470904
nsv1071694 CNV deletion 25765185
nsv1109378 CNV deletion 24896259
nsv1151621 CNV deletion 26484159
nsv519722 CNV loss 19592680
nsv956193 CNV deletion 24416366

Variation tolerance for RPN2 Gene

Residual Variation Intolerance Score: 75.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.89; 59.15% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RPN2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RPN2
Human Gene Mutation Database (HGMD)
RPN2

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RPN2 Gene

Disorders for RPN2 Gene

MalaCards: The human disease database

(2) MalaCards diseases for RPN2 Gene - From: HGMD and DISEASES

Disorder Aliases PubMed IDs
encephalitozoonosis
  • infection by encephalitozoon
microsporidiosis
  • infection by microspora
- elite association - COSMIC cancer census association via MalaCards
Search RPN2 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for RPN2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with RPN2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RPN2 Gene

Publications for RPN2 Gene

  1. Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity. (PMID: 29290612) Kottemann MC … Smogorzewska A (Molecular cell 2018) 3 4 58
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 45 58
  3. Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease. (PMID: 19668339) Potkin SG … Alzheimer's Disease Neuroimaging Initiative (PloS one 2009) 3 45 58
  4. RPN2 gene confers docetaxel resistance in breast cancer. (PMID: 18724378) Honma K … Ochiya T (Nature medicine 2008) 3 23 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58

Products for RPN2 Gene

Sources for RPN2 Gene

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