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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37E family of ribosomal proteins. It is located in t... See more...
Aliases for RPL37 Gene
Aliases for RPL37 Gene
External Ids for RPL37 Gene
- HGNC: 10347
- Entrez Gene: 6167
- Ensembl: ENSG00000145592
- OMIM: 604181
- UniProtKB: P61927
Previous GeneCards Identifiers for RPL37 Gene
- GC05M041139
- GC05M041924
- GC05M040878
- GC05M040876
- GC05M040866
- GC05M040783
Summaries for RPL37 Gene
-
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37E family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C2C2-type zinc finger-like motif. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
GeneCards Summary for RPL37 Gene
RPL37 (Ribosomal Protein L37) is a Protein Coding gene. Diseases associated with RPL37 include Noonan Syndrome 5 and Retinitis Pigmentosa 27. Among its related pathways are rRNA processing in the nucleus and cytosol and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include RNA binding and rRNA binding.
UniProtKB/Swiss-Prot Summary for RPL37 Gene
-
Binds to the 23S rRNA.
Additional gene information for RPL37 Gene
- HGNC(10347)
- Entrez Gene(6167)
- Ensembl(ENSG00000145592)
- OMIM(604181)
- UniProtKB(P61927)
- Open Targets Platform(ENSG00000145592)
- Search for RPL37 at DataMed
- Search for RPL37 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RPL37 Gene
Genomics for RPL37 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RPL37 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RPL37 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RPL37
- Top Transcription factor binding sites by QIAGEN in the RPL37 gene promoter:
-
- E47
- HSF2
- Ik-1
- Nkx3-1
- Nkx3-1 v1
- Nkx3-1 v2
- Nkx3-1 v3
- Nkx3-1 v4
- YY1
- ZID
Genomic Locations for RPL37 Gene
Genomic Locations for RPL37 Gene
- chr5:40,825,262-40,835,222
- (GRCh38/hg38)
- Size:
- 9,961 bases
- Orientation:
- Minus strand
- chr5:40,825,364-40,835,437
- (GRCh37/hg19)
- Size:
- 10,074 bases
- Orientation:
- Minus strand
Genomic View for RPL37 Gene
Genes around RPL37 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5p13.1 by HGNC
- 5p13.1 by Entrez Gene
- 5p13.1 by Ensembl
RPL37 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RPL37 Gene
Proteins for RPL37 Gene
-
Protein details for RPL37 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P61927-RL37_HUMAN
- Recommended name:
- 60S ribosomal protein L37
- Protein Accession:
- P61927
- B2R4H2
- P02403
- Q6IBB4
- Q99883
Protein attributes for RPL37 Gene
- Size:
- 97 amino acids
- Molecular mass:
- 11078 Da
- Cofactor:
- Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Quaternary structure:
- No Data Available
Protein Expression for RPL37 Gene
Post-translational modifications for RPL37 Gene
Other Protein References for RPL37 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ RPL37 Antibody
-
Custom Antibody ServicesOriGene Antibodies for RPL37
- Novus Biologicals Antibodies for RPL37
- Invitrogen Antibodies for RPL37 (AFLGC-RPL37)
-
Biorbyt antibodies for RPL37
-
Boster Bio Antibodies for RPL37
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RPL37
- Origene Custom Protein Services for RPL37
- Novus Biologicals proteins for RPL37
-
Abcam proteins for RPL37
No data available for DME Specific Peptides for RPL37 Gene
Domains & Families for RPL37 Gene
Gene Families for RPL37 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Ribosomal proteins
Protein Domains for RPL37 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RPL37 Gene
- GenScript: Design optimal peptide antigens:
-
- Ribosomal protein L37 (D6R9X9_HUMAN)
- Ribosomal protein L37 (D6RG19_HUMAN)
- G1.16 (RL37_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P61927- Family:
-
- Belongs to the eukaryotic ribosomal protein eL37 family.
Function for RPL37 Gene
Molecular function for RPL37 Gene
- UniProtKB/Swiss-Prot Function:
- Binds to the 23S rRNA.
- GENATLAS Biochemistry:
- 60S ribosomal protein L37,11kDa,overexpressed in colon cancer
Phenotypes From GWAS Catalog for RPL37 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA,TAS | 7545944 |
| GO:0003735 | structural constituent of ribosome | IEA,TAS | 7545944 |
| GO:0019843 | rRNA binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for RPL37 Gene
- GenomeRNAi human phenotypes for RPL37:
-
- no effect
- Decreased viability
- Decreased vaccinia virus (VACV) infection
- Negative genetic interaction between BLM-/- and BLM+/+
- Decreased shRNA abundance (Z-score < -2)
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased viability of wild-type and TP53 knockout cells, decreased TP53 protein expression ratio (wild-type / TP53 knockout cells)
- Decreased cell number
- Inconclusive
- Increased shRNA abundance (Z-score > 2)
- Increased S DNA content
- Decreased G3BP1 protein expression and assembly in stress granules and decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation
- Decreased viability in colon lineage
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RPL37 - Select products 50% OFF >
- * RPL37 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RPL37
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RPL37
-
Santa Cruz Biotechnology (SCBT) CRISPR for RPL37
miRNA for RPL37 Gene
- miRTarBase miRNAs that target RPL37
-
- hsa-miR-744-5p (MIRT037660)
- hsa-miR-324-5p (MIRT043070)
- hsa-miR-191-5p (MIRT045785)
- hsa-miR-34a-5p (MIRT047353)
- hsa-miR-17-5p (MIRT050856)
- hsa-miR-1277-5p (MIRT554631)
- hsa-miR-7159-5p (MIRT554632)
- hsa-miR-190a-3p (MIRT554633)
- hsa-miR-3065-5p (MIRT554634)
- hsa-miR-5011-5p (MIRT554635)
- hsa-miR-3074-3p (MIRT554636)
- hsa-miR-338-5p (MIRT554637)
- hsa-miR-188-3p (MIRT571346)
- hsa-miR-4474-5p (MIRT571347)
- hsa-miR-3618 (MIRT571348)
- hsa-miR-4433a-5p (MIRT571349)
- hsa-miR-1283 (MIRT571350)
- hsa-miR-4317 (MIRT571351)
- hsa-miR-5697 (MIRT571352)
- hsa-miR-2114-5p (MIRT571353)
- hsa-miR-5588-3p (MIRT571354)
- hsa-miR-4279 (MIRT649107)
- hsa-miR-1976 (MIRT649108)
- hsa-miR-3653-5p (MIRT649109)
- hsa-miR-325 (MIRT649110)
- hsa-miR-6747-3p (MIRT649111)
- hsa-miR-6727-3p (MIRT649112)
- hsa-miR-4722-3p (MIRT649113)
- hsa-miR-5571-5p (MIRT649114)
- hsa-miR-498 (MIRT672376)
- hsa-miR-4465 (MIRT672377)
- hsa-miR-26b-5p (MIRT672378)
- hsa-miR-26a-5p (MIRT672379)
- hsa-miR-1297 (MIRT672380)
- hsa-miR-6877-3p (MIRT672381)
- hsa-miR-6819-3p (MIRT672382)
- hsa-miR-378a-5p (MIRT675519)
- hsa-miR-6821-3p (MIRT675520)
- hsa-miR-6790-3p (MIRT675521)
- hsa-miR-372-5p (MIRT675522)
- hsa-miR-371a-5p (MIRT675523)
- hsa-miR-616-5p (MIRT675524)
- hsa-miR-373-5p (MIRT675525)
- hsa-miR-371b-5p (MIRT675526)
- hsa-miR-764 (MIRT675527)
- hsa-miR-3934-5p (MIRT675528)
- hsa-miR-125a-3p (MIRT675529)
- hsa-miR-6836-3p (MIRT675530)
- hsa-miR-514b-5p (MIRT675531)
- hsa-miR-513c-5p (MIRT675532)
- hsa-miR-6829-3p (MIRT675533)
- hsa-miR-6791-3p (MIRT675534)
- hsa-miR-6778-3p (MIRT675535)
- hsa-miR-562 (MIRT675536)
- hsa-miR-4482-3p (MIRT724298)
- hsa-miR-7159-3p (MIRT724299)
- hsa-miR-138-2-3p (MIRT724300)
- hsa-miR-1908-3p (MIRT724301)
- hsa-miR-10b-3p (MIRT724302)
- hsa-miR-4714-3p (MIRT724303)
- hsa-miR-4272 (MIRT724304)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RPL37
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Clone Products
- Applied Biological Materials (abm): Clones for RPL37 - Select products 50% OFF >
- * RPL37 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RPL37
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RPL37
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RPL37 Gene
Localization for RPL37 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 4 |
| nucleus | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
| GO:0005840 | ribosome | IEA | -- |
| GO:0022625 | cytosolic large ribosomal subunit | TAS | 7545944 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for RPL37 Gene
Pathways & Interactions for RPL37 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Viral mRNA Translation |
CFTR translational fidelity (class I mutations)
.79
.77
.53
|
|
| 2 | Influenza Viral RNA Transcription and Replication | ||
| 3 | rRNA processing in the nucleus and cytosol |
.89
|
|
| 4 | HIV Life Cycle |
.45
|
|
| 5 | Gene Expression |
.48
|
|
Pathways by source for RPL37 Gene
1 BioSystems pathway for RPL37 Gene
28 Reactome pathways for RPL37 Gene
1 KEGG pathway for RPL37 Gene
1 GeneGo (Thomson Reuters) pathway for RPL37 Gene
- CFTR translational fidelity (class I mutations)
Interacting Proteins for RPL37 Gene
GPS-Prot Interaction Network for RPL37
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | -- |
| GO:0006412 | translation | IEA,TAS | 7545944 |
| GO:0006413 | translational initiation | TAS | -- |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | -- |
| GO:0019083 | viral transcription | TAS | -- |
No data available for SIGNOR curated interactions for RPL37 Gene
Drugs & Compounds for RPL37 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Anisomycin | Experimental | Pharma | Target | JNK agonist, potent and specific, JNK, SAPK and p38 activator | 0 | |
| L-3-Phenyllactic acid | Experimental | Pharma | Target | 0 | ||
| puromycin | Experimental | Pharma | Target | 0 | ||
| PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE | Experimental | Pharma | Target | 0 | ||
| Virginiamycin S1 | Experimental | Pharma | Target | 0 |
Transcripts for RPL37 Gene
mRNA/cDNA for RPL37 Gene
- 1 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000274242 7573 nts (view in UCSC)
- ENST00000504562 505 nts (view in UCSC)
- ENST00000507642 425 nts (view in UCSC)
- ENST00000508493 553 nts (view in UCSC)
- ENST00000509877 637 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RPL37 - Select products 50% OFF >
- * RPL37 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RPL37
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RPL37
-
Santa Cruz Biotechnology (SCBT) CRISPR for RPL37
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RPL37
- Browse OriGene Inhibitory RNA Products For RPL37
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RPL37
Clone Products
- Applied Biological Materials (abm): Clones for RPL37 - Select products 50% OFF >
- * RPL37 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RPL37
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RPL37
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6a | · | 6b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||
| SP2: | - | - | |||||||||||||||||
| SP3: | - | ||||||||||||||||||
| SP4: | - |
Relevant External Links for RPL37 Gene
- GeneLoc Exon Structure for
- RPL37
Expression for RPL37 Gene
This gene is overexpressed in Lung (32.8), Peripheral blood mononuclear cells (13.1), Cervix (8.9), and Bone (6.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RPL37 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RPL37
SOURCE GeneReport for Unigene cluster for RPL37 Gene:
Hs.447582Evidence on tissue expression from TISSUES for RPL37 Gene
- Blood(4.9)
- Lung(4.9)
- Intestine(4.8)
- Muscle(4.8)
- Nervous system(4.8)
- Liver(4.4)
- Heart(4)
- Skin(3.8)
- Stomach(3.8)
- Kidney(3.4)
- Bone(3.3)
- Pancreas(3)
- Spleen(2.9)
- Lymph node(2.9)
- Bone marrow(2.9)
- Eye(2.7)
- Adrenal gland(2.4)
- Thyroid gland(2.2)
- Gall bladder(2.2)
Primer Products
-
OriGene qPCR primer pairs for RPL37
-
OriGene qPCR primer pairs and template standards for RPL37
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RPL37 Gene
Orthologs for RPL37 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RPL37 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| RPL37 30 |
|
||||
| -- 31 |
|
OneToMany | |||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RPL37 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Cow (Bos Taurus) |
Mammalia | RPL37 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC100360841 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Rpl37 30 17 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RPL37 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RPL37 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rpl37 30 |
|
||
| Str.11137 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | rpl37 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG9091 32 |
|
|
|
| RpL37a 30 31 |
|
OneToMany | |||
| CG9873 32 |
|
|
|||
| RpL37b 31 |
|
OneToMany | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000952 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | rpl-37 31 |
|
OneToMany | |
| W01D2.1 30 31 |
|
OneToMany | |||
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AFR688C 30 |
|
||
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0C01870g 30 |
|
||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RPL37A 30 31 33 |
|
OneToMany | |
| RPL37B 31 |
|
OneToMany | |||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT1G52300 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os02g0111700 30 |
|
||
| Barley (Hordeum vulgare) |
Liliopsida | Hv.12413 30 |
|
||
| Wheat (Triticum aestivum) |
Liliopsida | Ta.5687 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne | |
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | rpl3702 30 |
|
||
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU01966 30 |
|
- Species where no ortholog for RPL37 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Evolution for RPL37 Gene
- ENSEMBL:
- Gene Tree for RPL37 (if available)
- TreeFam:
- Gene Tree for RPL37 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RPL37: view image
Paralogs for RPL37 Gene
Pseudogenes.org Pseudogenes for RPL37 Gene
- PGOHUM00000290566
- PGOHUM00000291043
- PGOHUM00000291324
- PGOHUM00000291518
- PGOHUM00000291988
- PGOHUM00000292368
- PGOHUM00000294395
- PGOHUM00000294469
- PGOHUM00000295420
- PGOHUM00000295536
- PGOHUM00000296144
- PGOHUM00000296335
- PGOHUM00000297112
- PGOHUM00000297227
- PGOHUM00000297357
- PGOHUM00000297819
- PGOHUM00000297882
- PGOHUM00000298488
- PGOHUM00000298621
- PGOHUM00000300185
- PGOHUM00000300953
- PGOHUM00000301422
- PGOHUM00000302414
- PGOHUM00000303556
- PGOHUM00000304059
- PGOHUM00000305088
- PGOHUM00000289791
- PGOHUM00000290296
No data available for Paralogs for RPL37 Gene
Variants for RPL37 Gene
Residual Variation Intolerance Score:
36.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.18;
4.05% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RPL37 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RPL37
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RPL37 Gene
Disorders for RPL37 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| noonan syndrome 5 |
|
|
| retinitis pigmentosa 27 |
|
|
| osteogenesis imperfecta, type iv |
|
|
| diamond-blackfan anemia |
|
|
Search RPL37 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RPL37
No data available for UniProtKB/Swiss-Prot and Genatlas for RPL37 Gene
Publications for RPL37 Gene
- Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain. (PMID: 7545944) Barnard GF … Chen LB (Biochimica et biophysica acta 1994) 2 3 4 23
- A map of 75 human ribosomal protein genes. (PMID: 9582194) Kenmochi N … Page DC (Genome research 1998) 2 3 4
- Cell cycle, differentiation and tissue-independent expression of ribosomal protein L37. (PMID: 7588717) Su S … Bird RC (European journal of biochemistry 1995) 3 4 23
- CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolism. (PMID: 15485924) Schwartz EI … Maraia RJ (Molecular and cellular biology 2004) 3 23
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for RPL37 Gene
- Custom Antibody ServicesOriGene Antibodies for RPL37
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RPL37
- Origene Custom Protein Services for RPL37
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- Sino Biological Human cDNA Clone for RPL37
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- Novus Biologicals Antibodies for RPL37
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- Invitrogen Antibodies for RPL37 (AFLGC-RPL37)
- VectorBuilder Custom and pre-made DNA vectors for RPL37 (ie. gene expression, shRNA knockdown, CRISPR)
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- VectorBuilder CRISPR vectors for RPL37 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RPL37 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RPL37
- antibodies-online: Show 26 available RPL37 Antibodies ranked by validation data
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- antibodies-online: Search results for available RPL37 related products ranked by validation data
- antibodies-online: Show 13 available RPL37 Proteins ranked by validation data
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RPL37
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for RPL37
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- Boster Bio Antibodies for RPL37
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Sources for RPL37 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB