Aliases for RPL12 Gene
External Ids for RPL12 Gene
Previous GeneCards Identifiers for RPL12 Gene
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
GeneCards Summary for RPL12 Gene
RPL12 (Ribosomal Protein L12) is a Protein Coding gene. Diseases associated with RPL12 include Neuronopathy, Distal Hereditary Motor, Type Viii and Diamond-Blackfan Anemia. Among its related pathways are Viral mRNA Translation and HIV Life Cycle. Gene Ontology (GO) annotations related to this gene include structural constituent of ribosome. An important paralog of this gene is MRPL11.
UniProtKB/Swiss-Prot Summary for RPL12 Gene
Binds directly to 26S ribosomal RNA.