Aliases for RPL10 Gene
External Ids for RPL10 Gene
Previous GeneCards Identifiers for RPL10 Gene
This gene encodes a ribosomal protein that is a component of the 60S ribosome subunit. The related protein in chicken can bind to c-Jun and can repress c-Jun-mediated transcriptional activation. Some studies have detected an association between variation in this gene and autism spectrum disorders, though others do not detect this relationship. There are multiple pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
GeneCards Summary for RPL10 Gene
RPL10 (Ribosomal Protein L10) is a Protein Coding gene. Diseases associated with RPL10 include Mental Retardation, X-Linked, Syndromic, 35 and Autism X-Linked 5. Among its related pathways are rRNA processing in the nucleus and cytosol and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include structural constituent of ribosome. An important paralog of this gene is RPL10L.
UniProtKB/Swiss-Prot Summary for RPL10 Gene
Component of the large ribosomal subunit (PubMed:26290468). Plays a role in the formation of actively translating ribosomes (PubMed:26290468). May play a role in the embryonic brain development (PubMed:25316788).