Aliases for RPH3AL Gene
External Ids for RPH3AL Gene
Previous GeneCards Identifiers for RPH3AL Gene
The protein encoded by this gene plays a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells and plays a key role in insulin secretion by pancreatic cells. This gene is likely a tumor suppressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010]
GeneCards Summary for RPH3AL Gene
RPH3AL (Rabphilin 3A Like (Without C2 Domains)) is a Protein Coding gene. Diseases associated with RPH3AL include Medulloblastoma and Acute Contagious Conjunctivitis. Among its related pathways are Deregulation of Rab and Rab Effector Genes in Bladder Cancer. Gene Ontology (GO) annotations related to this gene include calcium ion binding and syntaxin binding. An important paralog of this gene is RPH3A.
UniProtKB/Swiss-Prot Summary for RPH3AL Gene
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.