Aliases for RPAP2 Gene
External Ids for RPAP2 Gene
Previous HGNC Symbols for RPAP2 Gene
Previous GeneCards Identifiers for RPAP2 Gene
GeneCards Summary for RPAP2 Gene
RPAP2 (RNA Polymerase II Associated Protein 2) is a Protein Coding gene. Diseases associated with RPAP2 include Glomuvenous Malformations. Among its related pathways are Tat-mediated elongation of the HIV-1 transcript and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA polymerase II CTD heptapeptide repeat phosphatase activity.
UniProtKB/Swiss-Prot Summary for RPAP2 Gene
Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.