Aliases for ROM1 Gene
External Ids for ROM1 Gene
Previous GeneCards Identifiers for ROM1 Gene
This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008]
GeneCards Summary for ROM1 Gene
ROM1 (Retinal Outer Segment Membrane Protein 1) is a Protein Coding gene. Diseases associated with ROM1 include Retinitis Pigmentosa 7 and Retinitis Pigmentosa. An important paralog of this gene is PRPH2.
UniProtKB/Swiss-Prot Summary for ROM1 Gene
Plays a role in rod outer segment (ROS) morphogenesis (By similarity). May play a role with PRPH2 in the maintenance of the structure of ROS curved disks (By similarity). Plays a role in the organization of the ROS and maintenance of ROS disk diameter (By similarity). Involved in the maintenance of the retina outer nuclear layer (By similarity).