Aliases for ROBO4 Gene
External Ids for ROBO4 Gene
Previous GeneCards Identifiers for ROBO4 Gene
GeneCards Summary for ROBO4 Gene
ROBO4 (Roundabout Guidance Receptor 4) is a Protein Coding gene. Diseases associated with ROBO4 include Aortic Valve Disease 3 and Diaphragmatic Hernia, Congenital. Among its related pathways are Development Slit-Robo signaling. An important paralog of this gene is SDK1.
UniProtKB/Swiss-Prot Summary for ROBO4 Gene
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function (PubMed:30455415).