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Aliases for RNY1 Gene

Subcategory (RNA class) for RNY1 Gene


Quality Score for this RNA gene is


Aliases for RNY1 Gene

  • RNA, Ro-Associated Y1 2 3 5
  • RNA, Y1 Small Cytoplasmic (Associated With Ro Protein) 2 3
  • HY1 3
  • Y1 3

External Ids for RNY1 Gene

ORGUL Members for RNY1 Gene

Previous GeneCards Identifiers for RNY1 Gene

  • GC07U990082
  • GC07M148316
  • GC07M148685
  • GC07M142763

Summaries for RNY1 Gene

Entrez Gene Summary for RNY1 Gene

  • Y RNAs are small noncoding RNAs that were originally identified as the RNA component of soluble ribonucleoproteins (RNPs) termed Ro RNPs. Ro RNPs are detected by autoimmune sera of patients suffering from rheumatic diseases, such as from systemic lupus erythematosus (MIM 152700) and Sjogren syndrome (MIM 270200). Ro RNPs consist of a Y RNA that is associated with the autoimmune antigen proteins Ro60 (TROVE2; MIM 600063) and La (SSB; MIM 109090), as well as other proteins. Four human Y RNAs have been identified: Y1, Y3 (RNY3; MIM 601822), Y4 (RNY4; MIM 601823), and Y5 (RNY5; MIM 601824). (Y2 is a truncated form of Y1.) Y RNAs are transcribed by RNA polymerase III and range in size from 83 to 112 nucleotides. They appear to have a functional role in chromosomal DNA replication (Christov et al., 2006 [PubMed 16943439]).[supplied by OMIM, Apr 2009]

GeneCards Summary for RNY1 Gene

RNY1 (RNA, Ro-Associated Y1) is an RNA Gene, and is affiliated with the Y RNA class.

Additional gene information for RNY1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNY1 Gene

Genomics for RNY1 Gene

GeneHancer (GH) Regulatory Elements for RNY1 Gene

Promoters and enhancers for RNY1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I148986 Promoter/Enhancer 1.6 Ensembl ENCODE 550.8 +0.1 108 2.6 PKNOX1 SMAD1 ARNT ARID4B SIN3A ZNF2 ZNF766 ZNF213 E2F8 ZNF143 GC07M148988 GHET1 RNY1 LOC155060 ZNF783 ZNF777 ZNF767P ZNF398 PDIA4 ENSG00000271664
GH07I148985 Enhancer 0.8 ENCODE 550.8 +1.6 1584 0.2 BCOR HDAC1 ARNT NFRKB TEAD4 ZNF384 GTF3C2 ADNP PRDM10 TRIM24 GC07M148988 GHET1 GC07P149011 RNY1 RNY3 PDIA4 GC07P149013
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RNY1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RNY1 gene promoter:

Genomic Locations for RNY1 Gene

Genomic Locations for RNY1 Gene
113 bases
Minus strand

Genomic View for RNY1 Gene

Genes around RNY1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNY1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNY1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNY1 Gene

Proteins for RNY1 Gene

Post-translational modifications for RNY1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNY1 Gene

Domains & Families for RNY1 Gene

Gene Families for RNY1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNY1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNY1 Gene

Function for RNY1 Gene

Molecular function for RNY1 Gene

GENATLAS Biochemistry:
small cytoplasmic ribonucleoprotein RY1,component of Ro ribonucleoprotein

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNY1 Gene

Localization for RNY1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNY1 Gene

Pathways & Interactions for RNY1 Gene

No Data Available

Interacting Proteins for RNY1 Gene

Gene Ontology (GO) - Biological Process for RNY1 Gene


No data available for Pathways by source and SIGNOR curated interactions for RNY1 Gene

Drugs & Compounds for RNY1 Gene

(1) Drugs for RNY1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
genes like me logo Genes that share compounds with RNY1: view

Transcripts for RNY1 Gene

mRNA/cDNA for RNY1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNY1 Gene

No ASD Table

Relevant External Links for RNY1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNY1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNY1 Gene

NURSA nuclear receptor signaling pathways regulating expression of RNY1 Gene:

genes like me logo Genes that share expression patterns with RNY1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNY1 Gene

Orthologs for RNY1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNY1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia Y_RNA 34
  • 100 (a)
(Canis familiaris)
Mammalia Y_RNA 34
  • 99 (a)
(Mus musculus)
Mammalia Rny1 34
  • 98 (a)
Species where no ortholog for RNY1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNY1 Gene

Gene Tree for RNY1 (if available)
Gene Tree for RNY1 (if available)

Paralogs for RNY1 Gene

No data available for Paralogs for RNY1 Gene

Variants for RNY1 Gene

Sequence variations from dbSNP and Humsavar for RNY1 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1001427014 -- 148,987,141(-) A/G non_coding_transcript_variant
rs1002442318 -- 148,987,187(-) A/G non_coding_transcript_variant
rs1003024439 -- 148,988,252(-) C/G upstream_transcript_variant
rs1003413624 -- 148,987,338(-) G/T upstream_transcript_variant
rs1003486173 -- 148,988,539(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for RNY1 Gene

Variant ID Type Subtype PubMed ID
nsv831183 CNV loss 17160897
nsv608973 CNV loss 21841781
nsv528358 CNV loss 19592680

Additional Variant Information for RNY1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNY1 Gene

Disorders for RNY1 Gene

Additional Disease Information for RNY1

No disorders were found for RNY1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNY1 Gene

Publications for RNY1 Gene

  1. Genes for two small cytoplasmic Ro RNAs are adjacent and appear to be single-copy in the human genome. (PMID: 6187471) Wolin SL … Steitz JA (Cell 1983) 2 3 58
  2. DPP-IV inhibition enhances the antilipolytic action of NPY in human adipose tissue. (PMID: 19175376) Kos K … McTernan PG (Diabetes, obesity & metabolism 2009) 22 58
  3. Functional requirement of noncoding Y RNAs for human chromosomal DNA replication. (PMID: 16943439) Christov CP … Krude T (Molecular and cellular biology 2006) 3 58
  4. An arachidonic acid-preferring acyl-CoA synthetase is a hormone-dependent and obligatory protein in the signal transduction pathway of steroidogenic hormones. (PMID: 15956337) Cornejo Maciel F … Podestá EJ (Journal of molecular endocrinology 2005) 22 58
  5. Neuropeptide Y expression, localization and cellular transducing effects in HUVEC. (PMID: 15850450) Silva AP … Grouzmann E (Biology of the cell 2005) 22 58

Products for RNY1 Gene

Sources for RNY1 Gene

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