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Aliases for RNU6-8 Gene

Subcategory (RNA class) for RNU6-8 Gene

snRNA

Quality Score for this RNA gene is

3

Aliases for RNU6-8 Gene

  • RNA, U6 Small Nuclear 8 2 3 5
  • U6-8 3

External Ids for RNU6-8 Gene

ORGUL Members for RNU6-8 Gene

Previous GeneCards Identifiers for RNU6-8 Gene

  • GC00U922497
  • GC03M098524
  • GC14M032674
  • GC14M032676

Summaries for RNU6-8 Gene

GeneCards Summary for RNU6-8 Gene

RNU6-8 (RNA, U6 Small Nuclear 8) is an RNA Gene, and is affiliated with the snRNA class.

Additional gene information for RNU6-8 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU6-8 Gene

Genomics for RNU6-8 Gene

GeneHancer (GH) Regulatory Elements for RNU6-8 Gene

Promoters and enhancers for RNU6-8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I032200 Promoter/Enhancer 2.1 FANTOM5 Ensembl ENCODE dbSUPER 550.8 +0.9 875 4.1 PKNOX1 CLOCK SMAD1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 GC14P032203 RNU6-7 RNU6-8 HECTD1 NPAS3 AKAP6 ARHGAP5
GH14I032074 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11.5 +126.1 126115 5.9 HDGF PKNOX1 CLOCK FOXA2 ARNT ARID4B NEUROD1 SIN3A FEZF1 DMAP1 ARHGAP5-AS1 ARHGAP5 RNU6-8 RNU6-7 RPL21P5 LOC101927124 GC14P032154
GH14I032134 Enhancer 1 ENCODE 22.5 +68.4 68409 0.1 PKNOX1 CLOCK ARNT NEUROD1 FEZF1 ZNF2 FOS SP3 REST ZNF662 ARHGAP5 RNU6-8 LOC101927124 NPAS3 RNU6-7 HECTD1 DTD2 GC14P032154 ARHGAP5-AS1
GH14I032082 Enhancer 1.3 Ensembl ENCODE dbSUPER 11.8 +119.8 119784 3 ELF3 FOXA2 FEZF1 DNMT3B THRB ZSCAN9 RARA SLC30A9 SMARCC2 CREM RNU6-8 RNU6-7 ARHGAP5-AS1 ARHGAP5 GC14P032154
GH14I032229 Enhancer 1.1 FANTOM5 Ensembl ENCODE 12.4 -27.4 -27416 2.1 CTCF RXRA JUN CEBPB RAD21 YY1 MAFF JUND ATF3 STAT3 RNU6-8 RNU6-7 LOC100533787
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RNU6-8 on UCSC Golden Path with GeneCards custom track

Genomic Locations for RNU6-8 Gene

Genomic Locations for RNU6-8 Gene
chr14:32,203,163-32,203,269
(GRCh38/hg38)
Size:
107 bases
Orientation:
Minus strand
chr14:32,672,369-32,672,475
(GRCh37/hg19)

Genomic View for RNU6-8 Gene

Genes around RNU6-8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU6-8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU6-8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU6-8 Gene

Proteins for RNU6-8 Gene

Post-translational modifications for RNU6-8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU6-8 Gene

Domains & Families for RNU6-8 Gene

Gene Families for RNU6-8 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU6-8: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU6-8 Gene

Function for RNU6-8 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU6-8 Gene

Localization for RNU6-8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNU6-8 Gene

Pathways & Interactions for RNU6-8 Gene

SuperPathways for RNU6-8 Gene

No Data Available

Interacting Proteins for RNU6-8 Gene

Gene Ontology (GO) - Biological Process for RNU6-8 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU6-8 Gene

Drugs & Compounds for RNU6-8 Gene

No Compound Related Data Available

Transcripts for RNU6-8 Gene

mRNA/cDNA for RNU6-8 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNU6-8 Gene

No ASD Table

Relevant External Links for RNU6-8 Gene

GeneLoc Exon Structure for
RNU6-8
ECgene alternative splicing isoforms for
RNU6-8

Expression for RNU6-8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU6-8 Gene

genes like me logo Genes that share expression patterns with RNU6-8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU6-8 Gene

Orthologs for RNU6-8 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU6-8 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia U6 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia U6 34
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia U6 34
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm26243 34
  • 100 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia U6 34
  • 100 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii U6 34
  • 96 (a)
OneToMany
Species where no ortholog for RNU6-8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RNU6-8 Gene

ENSEMBL:
Gene Tree for RNU6-8 (if available)
TreeFam:
Gene Tree for RNU6-8 (if available)

Paralogs for RNU6-8 Gene

No data available for Paralogs for RNU6-8 Gene

Variants for RNU6-8 Gene

Sequence variations from dbSNP and Humsavar for RNU6-8 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000872604 -- 32,204,858(-) G/T upstream_transcript_variant
rs1001592315 -- 32,205,261(-) T/A upstream_transcript_variant
rs1002481907 -- 32,203,609(-) C/T upstream_transcript_variant
rs1002908074 -- 32,204,113(-) G/T upstream_transcript_variant
rs1003610273 -- 32,203,255(-) T/C non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for RNU6-8 Gene

Variant ID Type Subtype PubMed ID
dgv134n111 CNV deletion 26073780
dgv135n111 CNV deletion 26073780
esv1002005 CNV deletion 20482838
esv1972594 CNV deletion 18987734
esv2523863 CNV deletion 19546169
esv2672070 CNV deletion 23128226
esv2733339 CNV deletion 23290073
esv2758743 CNV gain+loss 17122850
esv2758896 CNV gain+loss 17122850
esv2758920 CNV gain+loss 17122850
esv2759205 CNV gain 17122850
esv3259 CNV loss 18987735
esv3545926 CNV deletion 23714750
esv3574862 CNV loss 25503493
esv3574863 CNV loss 25503493
esv3584226 CNV gain 25503493
esv3643383 CNV gain 21293372
esv3643384 CNV loss 21293372
esv3643385 CNV gain 21293372
esv3890859 CNV loss 25118596
esv3891198 CNV gain 25118596
esv8509 CNV loss 19470904
esv996651 CNV deletion 20482838
nsv1041463 CNV gain 25217958
nsv1068280 CNV deletion 25765185
nsv1160555 CNV deletion 26073780
nsv1578 CNV insertion 18451855
nsv2385 CNV insertion 18451855
nsv3041 CNV insertion 18451855
nsv428427 CNV gain 18775914
nsv469845 CNV loss 16826518
nsv470101 CNV loss 18288195
nsv512148 CNV loss 21212237
nsv524931 CNV gain 19592680
nsv545381 CNV gain 21841781
nsv545382 CNV loss 21841781
nsv569803 CNV gain 21841781
nsv578188 CNV loss 21841781
nsv7462 OTHER inversion 18451855
nsv826912 CNV gain 20364138
nsv828360 CNV loss 20364138
nsv829809 CNV loss 17160897
nsv832764 CNV gain 17160897
nsv833704 CNV gain 17160897
nsv953938 CNV deletion 24416366
nsv956356 CNV deletion 24416366
nsv9662 CNV gain 18304495

Additional Variant Information for RNU6-8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU6-8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU6-8 Gene

Disorders for RNU6-8 Gene

Additional Disease Information for RNU6-8

No disorders were found for RNU6-8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU6-8 Gene

Publications for RNU6-8 Gene

  1. Multiple, dispersed human U6 small nuclear RNA genes with varied transcriptional efficiencies. (PMID: 12711679) Domitrovich AM … Kunkel GR (Nucleic acids research 2003) 2 3 58
  2. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3

Products for RNU6-8 Gene

Sources for RNU6-8 Gene

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