Aliases for RNU6-2 Gene

Subcategory (RNA class) for RNU6-2 Gene

snRNA

Number of RNA Genes sources:

3 / 17

Aliases for RNU6-2 Gene

  • RNA, U6 Small Nuclear 2 2 3 5
  • RNU6-2 2 5
  • U6-2 2 3
  • RF00026 168
  • 6AHD_F 167
  • 5Z56_F 167
  • 6QW6_6 167
  • 6FF7_6 167
  • 6AH0_F 167
  • 6ICZ_F 167
  • 5YZG_F 167
  • 3JCR_N 167
  • 5O9Z_6 167
  • 5XJC_F 167
  • RNU6-9 2
  • 5Z58_F 167
  • 6FF4_6 167
  • 6ID0_F 167
  • 5MQF_6 167
  • 5Z57_F 167
  • 6ID1_F 167
  • 6QX9_6 167
  • 6QDV_6 167
  • RNU6-1 2

External Ids for RNU6-2 Gene

Previous GeneCards Identifiers for RNU6-2 Gene

  • GC10P013302
  • GC07M122820

Summaries for RNU6-2 Gene

GeneCards Summary for RNU6-2 Gene

RNU6-2 (RNA, U6 Small Nuclear 2) is an RNA Gene, and is affiliated with the snRNA class.

Rfam classification for RNU6-2 Gene

Additional gene information for RNU6-2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU6-2 Gene

Genomics for RNU6-2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for RNU6-2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J001019 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 5.9 +3.5 3527 12.5 ZNF221 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A ATF7 TEAD4 PRDM10 ZNF629 TMEM259 CNN2 GRIN3B DAZAP1 CIRBP MIER2 LOC100288123 TCF3 PTBP1 ABCA7
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RNU6-2 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the RNU6-2 gene promoter:
  • ATF6
  • COUP
  • COUP-TF
  • FOXD1
  • HOXA9
  • HOXA9B
  • Meis-1
  • Meis-1b
  • NRSF form 1
  • NRSF form 2

Genomic Locations for RNU6-2 Gene

Genomic Locations for RNU6-2 Gene
chr19:1,021,522-1,021,628
(GRCh38/hg38)
Size:
107 bases
Orientation:
Plus strand
chr10:13,259,269-13,259,375
(GRCh37/hg19)
Size:
107 bases
Orientation:
Plus strand

Genomic View for RNU6-2 Gene

Genes around RNU6-2 on UCSC Golden Path with GeneCards custom track
RNU6-2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
RNU6-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU6-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU6-2 Gene

Proteins for RNU6-2 Gene

Post-translational modifications for RNU6-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU6-2 Gene

Domains & Families for RNU6-2 Gene

Gene Families for RNU6-2 Gene

genes like me logo Genes that share domains with RNU6-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RNU6-2 Gene

Function for RNU6-2 Gene

Phenotypes From GWAS Catalog for RNU6-2 Gene

Gene Ontology (GO) - Molecular Function for RNU6-2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030621 U4 snRNA binding IEA --
genes like me logo Genes that share ontologies with RNU6-2: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU6-2 Gene

Localization for RNU6-2 Gene

Gene Ontology (GO) - Cellular Components for RNU6-2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005688 U6 snRNP IEA --
GO:0046540 U4/U6 x U5 tri-snRNP complex IEA --
genes like me logo Genes that share ontologies with RNU6-2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for RNU6-2 Gene

Pathways & Interactions for RNU6-2 Gene

PathCards logo

SuperPathways for RNU6-2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RNU6-2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000244 spliceosomal tri-snRNP complex assembly IEA --
GO:0000353 formation of quadruple SL/U4/U5/U6 snRNP IEA --
genes like me logo Genes that share ontologies with RNU6-2: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for RNU6-2 Gene

Drugs & Compounds for RNU6-2 Gene

No Compound Related Data Available

Transcripts for RNU6-2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for RNU6-2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00001EC8D7_9606 snRNA 107 6

HGNC: 34269, 34270,

RefSeq: NR_104080, NR_125730,

Ensembl: ENST00000383898 (view in UCSC) , ENST00000384627 (view in UCSC) , ENST00000384776 (view in UCSC) ,

PDBe: 5XJC_F, 5YZG_F, 5Z56_F, 5Z57_F, 5Z58_F,

Rfam: RF00026,

ENA: X07425.1:266..372:ncRNA, X59362.1:1..107:ncRNA,

URS000035C796_9606 snRNA 106 4

HGNC: 10227,

RefSeq: NR_004394,

PDBe: 3JCR_N, 5MQF_6, 5O9Z_6, 6QDV_6, 6QX9_6,

ENA: M14486.1:329..434:ncRNA,

URS0000532A91_9606 snRNA 87 1

ENA: AF114985.1:266..352:ncRNA,

URS0000E60BBB_9606 snRNA 86 1

PDBe: 6QW6_6,

URS000004A895_9606 snRNA 64 1

ENA: AY623052.1:486..549:ncRNA,

RNU6-2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for RNU6-2 Gene

No ASD Table

Relevant External Links for RNU6-2 Gene

GeneLoc Exon Structure for
RNU6-2

No data available for mRNA/cDNA for RNU6-2 Gene

Expression for RNU6-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RNU6-2 Gene

genes like me logo Genes that share expression patterns with RNU6-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU6-2 Gene

Orthologs for RNU6-2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU6-2 Gene

Organism Taxonomy Gene Similarity Type Details
Mouse
(Mus musculus)
Mammalia Gm22823 31
  • 100 (a)
ManyToMany
Chimpanzee
(Pan troglodytes)
Mammalia U6 31
  • 100 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia U6 31
  • 100 (a)
ManyToMany
Dog
(Canis familiaris)
Mammalia U6 31
  • 100 (a)
ManyToMany
Chicken
(Gallus gallus)
Aves U6 31
  • 100 (a)
OneToMany
Species where no ortholog for RNU6-2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for RNU6-2 Gene

ENSEMBL:
Gene Tree for RNU6-2 (if available)
TreeFam:
Gene Tree for RNU6-2 (if available)

Paralogs for RNU6-2 Gene

No data available for Paralogs for RNU6-2 Gene

Variants for RNU6-2 Gene

Additional dbSNP identifiers (rs#s) for RNU6-2 Gene

Structural Variations from Database of Genomic Variants (DGV) for RNU6-2 Gene

Variant ID Type Subtype PubMed ID
dgv134n111 CNV deletion 26073780
dgv135n111 CNV deletion 26073780
esv1002005 CNV deletion 20482838
esv1972594 CNV deletion 18987734
esv2523863 CNV deletion 19546169
esv2672070 CNV deletion 23128226
esv2733339 CNV deletion 23290073
esv2758743 CNV gain+loss 17122850
esv2758896 CNV gain+loss 17122850
esv2758920 CNV gain+loss 17122850
esv2759205 CNV gain 17122850
esv3259 CNV loss 18987735
esv3545926 CNV deletion 23714750
esv3574862 CNV loss 25503493
esv3574863 CNV loss 25503493
esv3584226 CNV gain 25503493
esv3643383 CNV gain 21293372
esv3643384 CNV loss 21293372
esv3643385 CNV gain 21293372
esv3890859 CNV loss 25118596
esv3891198 CNV gain 25118596
esv8509 CNV loss 19470904
esv996651 CNV deletion 20482838
nsv1041463 CNV gain 25217958
nsv1068280 CNV deletion 25765185
nsv1160555 CNV deletion 26073780
nsv1578 CNV insertion 18451855
nsv2385 CNV insertion 18451855
nsv3041 CNV insertion 18451855
nsv428427 CNV gain 18775914
nsv469845 CNV loss 16826518
nsv470101 CNV loss 18288195
nsv512148 CNV loss 21212237
nsv524931 CNV gain 19592680
nsv545381 CNV gain 21841781
nsv545382 CNV loss 21841781
nsv569803 CNV gain 21841781
nsv578188 CNV loss 21841781
nsv7462 OTHER inversion 18451855
nsv826912 CNV gain 20364138
nsv828360 CNV loss 20364138
nsv829809 CNV loss 17160897
nsv832764 CNV gain 17160897
nsv833704 CNV gain 17160897
nsv953938 CNV deletion 24416366
nsv956356 CNV deletion 24416366
nsv9662 CNV gain 18304495

Additional Variant Information for RNU6-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU6-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for RNU6-2 Gene

Disorders for RNU6-2 Gene

Additional Disease Information for RNU6-2

No disorders were found for RNU6-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU6-2 Gene

Publications for RNU6-2 Gene

  1. Common genetic variation and performance on standardized cognitive tests. (PMID: 20125193) Cirulli ET … Goldstein DB (European journal of human genetics : EJHG 2010) 3 41
  2. Multiple, dispersed human U6 small nuclear RNA genes with varied transcriptional efficiencies. (PMID: 12711679) Domitrovich AM … Kunkel GR (Nucleic acids research 2003) 2 3

Products for RNU6-2 Gene

Sources for RNU6-2 Gene