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Aliases for RNU4-2 Gene
Data sources for RNU4-2 Gene:
Subcategory (RNA class) for RNU4-2 Gene
snRNA
Aliases for RNU4-2 Gene
- RNA, U4 Small Nuclear 2 (HGNC, NCBI Entrez Gene, Ensembl)
- RNA, U4 Small Nuclear 1B (HGNC, NCBI Entrez Gene)
- RNA, U4B1 Small Nuclear (HGNC, NCBI Entrez Gene)
- RNA, U4C Small Nuclear (HGNC, NCBI Entrez Gene)
- U4A (HGNC, NCBI Entrez Gene)
- U4b (HGNC, NCBI Entrez Gene)
- U4c (HGNC, NCBI Entrez Gene)
- RNU4-1B (NCBI Entrez Gene)
- RF00015 (Rfam)
- RNU4B1 (NCBI Entrez Gene)
- RNU4-2 (Ensembl)
- RNU4C (NCBI Entrez Gene)
External Ids for RNU4-2 Gene
- HGNC: 10193
- NCBI Entrez Gene: 26834
- Ensembl: ENSG00000202538
Previous HGNC Symbols for RNU4-2 Gene
- RNU4C
- RNU4-1B
- RNU4B1
Previous GeneCards Identifiers for RNU4-2 Gene
- GC12U900989
- GC12M119219
- GC12M120729
- GC12M117737
Summaries for RNU4-2 Gene
GeneCards Summary for RNU4-2 Gene
RNU4-2 (RNA, U4 Small Nuclear 2) is an RNA Gene, and is affiliated with the snRNA class. Among its related pathways are mRNA Splicing - Major Pathway and RNA transport.
Rfam classification for RNU4-2 Gene
-
U4 spliceosomal RNA
Additional gene information for RNU4-2 Gene
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU4-2 Gene
Genomics for RNU4-2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RNU4-2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RNU4-2 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for RNU4-2 Gene
Latest Assembly
- chr12:120,291,760-120,291,903
- (GRCh38/hg38)
- Size:
- 144 bases
- Orientation:
- Minus strand
Previous Assembly
- chr12:120,729,566-120,729,706
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 141 bases
- Orientation:
- Minus strand
- chr12:120,729,566-120,729,706
- (GRCh37/hg19 by Ensembl)
- Size:
- 141 bases
- Orientation:
- Minus strand
Genomic View for RNU4-2 Gene
Genes around RNU4-2 on UCSC Golden Path with GeneCards custom track
RNU4-2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
- Cytogenetic band:
-
- 12q24.31 by HGNC
- 12q24.23 by Entrez Gene
- 12q24.23 by Ensembl
RNU4-2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RNU4-2 Gene
Proteins for RNU4-2 Gene
Post-translational modifications for RNU4-2 Gene
No Post-translational modifications
No data available for DME Specific Peptides for RNU4-2 Gene
Domains & Families for RNU4-2 Gene
Gene Families for RNU4-2 Gene
- HGNC:
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RNU4-2 Gene
Function for RNU4-2 Gene
Phenotypes From GWAS Catalog for RNU4-2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0017070 | U6 snRNA binding | IEA | -- |
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for RNU4-2 - Starting at $85 >
- * RNU4-2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
Inhibitory RNAs for research
Clone products for research
Cell Lines for research
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU4-2 Gene
Localization for RNU4-2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005687 | U4 snRNP | IEA | -- |
| GO:0046540 | U4/U6 x U5 tri-snRNP complex | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for RNU4-2 Gene
Pathways & Interactions for RNU4-2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RNA transport | ||
| 2 | mRNA Splicing - Major Pathway |
.47
|
|
Pathways by source for RNU4-2 Gene
2 KEGG pathways for RNU4-2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000244 | spliceosomal tri-snRNP complex assembly | IEA | -- |
| GO:0000353 | formation of quadruple SL/U4/U5/U6 snRNP | IEA | -- |
No data available for Interacting Proteins and SIGNOR curated interactions for RNU4-2 Gene
Transcripts for RNU4-2 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for RNU4-2 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS0000149178_9606 | snRNA | 141 | 3 |
RefSeq: NR_003137, Ensembl: ENST00000365668 (view in UCSC) , Rfam: RF00015, |
| URS0000200C70_9606 | snRNA | 144 | 2 |
PDBe: 5O9Z_4, ENA: V00592.1:1..145:ncRNA, |
| URS000000C8CD_9606 | snRNA | 144 | 1 |
ENA: M15957.1:271..414:ncRNA, |
| URS00004D7446_9606 | snRNA | 144 | 1 |
ENA: K00472.1:1..145:ncRNA, |
| URS00008FED2D_9606 | snRNA | 144 | 1 |
PDBe: 3JCR_M, |
RNU4-2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for RNU4-2 Gene
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for RNU4-2 - Starting at $85 >
- * RNU4-2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
Inhibitory RNAs for research
Clone products for research
Relevant External Links for RNU4-2 Gene
- GeneLoc Exon Structure for
- RNU4-2
Expression for RNU4-2 Gene
mRNA differential expression in normal tissues according to GTEx for RNU4-2 Gene
This gene is overexpressed in Whole Blood (x4.4).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RNU4-2
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU4-2 Gene
Orthologs for RNU4-2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Oppossum (Monodelphis domestica) |
Mammalia | U4 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Gm24407 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | U4 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | U4 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | U4 31 |
|
OneToOne | |
| Chimpanzee (Pan troglodytes) |
Mammalia | U4 31 |
|
ManyToMany | |
| Chicken (Gallus gallus) |
Aves | U4 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | U4 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | U4 31 31 31 |
|
ManyToMany |
- Species where no ortholog for RNU4-2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Paralogs for RNU4-2 Gene
No data available for Paralogs for RNU4-2 Gene
Variants for RNU4-2 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Additional Variant Information for RNU4-2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RNU4-2
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for RNU4-2 Gene
Disorders for RNU4-2 Gene
Additional Disease Information for RNU4-2
No disorders were found for RNU4-2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU4-2 Gene
Publications for RNU4-2 Gene
- Genes for human U4 small nuclear RNA. (PMID: 3582982) Bark C … Pettersson U (Gene 1986) 2 3
- RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
- Toward a complete human genome sequence. (PMID: 9847074) Sanger Center … Genome Sequencing Center (Genome research 1998) 3
- Primary and secondary structures of chicken, rat and man nuclear U4 RNAs. Homologies with U1 and U5 RNAs. (PMID: 6169000) Krol A … Jacob M (Nucleic acids research 1981) 3
ExternalLinks
Products for RNU4-2 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RNU4-2
- Origene Custom Protein Services for RNU4-2
- Browse OriGene Inhibitory RNA Products For RNU4-2
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for RNU4-2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RNU4-2
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for RNU4-2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for RNU4-2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RNU4-2
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for RNU4-2
Sources for RNU4-2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB