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RNPEPL1 (Arginyl Aminopeptidase Like 1) is a Protein Coding gene. Diseases associated with RNPEPL1 include Venous Hemangioma. Gene Ontology (GO) annotations related to this gene include binding and aminopeptidase activity. An important paralog of this gene is RNPEP.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004177 | aminopeptidase activity | IEA | -- |
GO:0008233 | peptidase activity | IEA | -- |
GO:0008237 | metallopeptidase activity | IEA | -- |
GO:0008270 | zinc ion binding | IEA | -- |
GO:0016787 | hydrolase activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006508 | proteolysis | IEA,IDA | 11017071 |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | · | 12c | · | 12d | ^ | 13 | ^ | 14a | · | 14b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
SP3: | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
SP5: | |||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | |||||||||||||||||||||||||||||||||||||||||
SP7: | - | ||||||||||||||||||||||||||||||||||||||||||
SP8: | - |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RNPEPL1 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RNPEPL1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RNPEPL1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Rnpepl1 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Rnpepl1 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | RNPEPL1 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | RNPEPL1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | RNPEPL1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | RNPEPL1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rnpepl1 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | LOC398435 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | LOC100535895 30 |
|
||
RNPEPL1 31 |
|
OneToOne | |||
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | LAP2 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1454498603 | A colorectal cancer sample |
p.Val478Met |
|||
rs35746075 | Benign: not provided | 240,575,118(+) |
A/G NM_018226.6(RNPEPL1):c.1377A>G (p.Pro459=) |
SYNONYMOUS | |
rs76384945 | Benign: not provided | 240,573,229(+) |
C/T NM_018226.6(RNPEPL1):c.789C>T (p.Ala263=) |
SYNONYMOUS |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2759119 | CNV | gain | 17122850 |
esv3575343 | CNV | gain | 25503493 |
esv3594802 | CNV | gain | 21293372 |
nsv1001262 | CNV | gain | 25217958 |
nsv10226 | CNV | gain | 18304495 |
nsv1071664 | CNV | deletion | 25765185 |
nsv1144928 | CNV | deletion | 24896259 |
nsv470529 | CNV | loss | 18288195 |
nsv482062 | CNV | gain | 20164927 |
nsv834586 | CNV | loss | 17160897 |
nsv955291 | CNV | deletion | 24416366 |
nsv999050 | CNV | gain | 25217958 |
Disorder | Aliases | PubMed IDs |
---|---|---|
venous hemangioma |
|
|