Aliases for RNGTT Gene
External Ids for RNGTT Gene
Previous GeneCards Identifiers for RNGTT Gene
GeneCards Summary for RNGTT Gene
RNGTT (RNA Guanylyltransferase And 5'-Phosphatase) is a Protein Coding gene. Diseases associated with RNGTT include Cecum Carcinoma and Cecum Adenocarcinoma. Among its related pathways are Formation of HIV-1 elongation complex containing HIV-1 Tat and HIV Life Cycle. Gene Ontology (GO) annotations related to this gene include GTP binding and protein tyrosine phosphatase activity. An important paralog of this gene is DUSP11.
UniProtKB/Swiss-Prot Summary for RNGTT Gene
Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.