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This gene encodes an integral membrane protein that contains a RING-type zinc finger. The encoded protein may interact with multiple transient receptor potential cation channel subfamily C (TRPC) proteins and regulate the trafficking and insertion of these proteins into the plasma membrane. [provided by RefSeq, Mar 2016]
RNF24 (Ring Finger Protein 24) is a Protein Coding gene. An important paralog of this gene is RNF122.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 25416956 |
GO:0008270 | zinc ion binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO:0061630 | ubiquitin protein ligase activity | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000139 | Golgi membrane | IEA | -- |
GO:0005794 | Golgi apparatus | IBA,IDA | -- |
GO:0012505 | endomembrane system | IBA | 21873635 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016567 | protein ubiquitination | IEA | -- |
ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||
SP2: | - | - | |||||||||||||||||||
SP3: | - |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RNF24 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | RNF24 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RNF24 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RNF24 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | RNF24 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Rnf24 30 17 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | RNF24 30 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100485988 30 |
|
||
Str.3540 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.15788 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | rnf24 30 31 |
|
OneToOne | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3645053 | CNV | loss | 21293372 |
esv3645054 | CNV | gain | 21293372 |
esv3645064 | CNV | loss | 21293372 |
esv3645065 | CNV | loss | 21293372 |
nsv1073040 | CNV | deletion | 25765185 |
nsv1116844 | CNV | deletion | 24896259 |
nsv1133291 | CNV | tandem duplication | 24896259 |
nsv472501 | CNV | novel sequence insertion | 20440878 |
nsv527924 | CNV | gain | 19592680 |
nsv585308 | CNV | loss | 21841781 |
nsv828673 | CNV | gain | 20364138 |
No disorders were found for RNF24 Gene.