Aliases for RNF227 Gene

Aliases for RNF227 Gene

  • Ring Finger Protein 227 2 3 5
  • Long Intergenic Non-Protein Coding RNA 2581 2 3 4
  • RING Finger Protein 227 3 4
  • LINC02581 3 4

External Ids for RNF227 Gene

Previous HGNC Symbols for RNF227 Gene

  • LINC02581

Summaries for RNF227 Gene

GeneCards Summary for RNF227 Gene

RNF227 (Ring Finger Protein 227) is a Protein Coding gene. An important paralog of this gene is RNF224.

Additional gene information for RNF227 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RNF227 Gene

Genomics for RNF227 Gene

GeneHancer (GH) Regulatory Elements for RNF227 Gene

Promoters and enhancers for RNF227 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J007914 Promoter/Enhancer 1.8 Ensembl ENCODE CraniofacialAtlas 509.4 +0.3 335 2.9 EP300 TCF12 SIN3A NRF1 USF1 PHF8 ZIC2 REST POLR2A ZBTB11 RNF227 lnc-RNF227-1 piR-59873 KCNAB3 NAA38 CYB5D1 TMEM88 GUCY2D ALOX15B
GH17J007917 Enhancer 0.2 Ensembl 505.9 -1.8 -1825 0.6 RNF227 lnc-RNF227-1 GUCY2D NAA38 CYB5D1 TMEM88 ALOX15B lnc-TRAPPC1-3
GH17J007929 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 6.3 -15.7 -15725 5.6 EP300 ZBTB40 CTCF ZSCAN5C TCF12 SIN3A NRF1 POLR2G SP1 RBAK KCNAB3 CNTROB ENSG00000262730 TRAPPC1 piR-45406 PFAS DVL2 SCARNA21 CHD3 SNORD10
GH17J007921 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas 5.7 -6.5 -6462 1.7 SP1 TEAD4 RCOR1 POLR2A CREB1 MEF2B NBN NR2F2 POU2F2 IKZF1 KCNAB3 RNF227 lnc-TRAPPC1-3
GH17J007989 Promoter/Enhancer 1.3 ENCODE CraniofacialAtlas 6.5 -73.9 -73861 1.7 ZNF217 CTCF TCF12 NRF1 POLR2G PHF8 ZNF639 ZIC2 ZBTB10 POLR2A KCNAB3 ALOX15B CNTROB TRAPPC1 SCARNA21 CHD3 NAA38 TMEM88 CYB5D1 RNF227
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RNF227 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RNF227

Genomic Locations for RNF227 Gene

Genomic Locations for RNF227 Gene
2,955 bases
Minus strand
2,632 bases
Minus strand

Genomic View for RNF227 Gene

Genes around RNF227 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF227 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF227 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF227 Gene

Proteins for RNF227 Gene

  • Protein details for RNF227 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RING finger protein 227
    Protein Accession:
    Secondary Accessions:
    • A0A1B0GVC2

    Protein attributes for RNF227 Gene

    190 amino acids
    Molecular mass:
    21006 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RNF227 Gene

Post-translational modifications for RNF227 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RNF227 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF227 Gene

Domains & Families for RNF227 Gene

Gene Families for RNF227 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for RNF227 Gene

genes like me logo Genes that share domains with RNF227: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RNF227 Gene

Function for RNF227 Gene

Phenotypes From GWAS Catalog for RNF227 Gene

Gene Ontology (GO) - Molecular Function for RNF227 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with RNF227: view

Phenotypes for RNF227 Gene

genes like me logo Genes that share phenotypes with RNF227: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNF227 Gene

Localization for RNF227 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNF227 Gene

Pathways & Interactions for RNF227 Gene

PathCards logo

SuperPathways for RNF227 Gene

No Data Available

Interacting Proteins for RNF227 Gene


Gene Ontology (GO) - Biological Process for RNF227 Gene


No data available for Pathways by source and SIGNOR curated interactions for RNF227 Gene

Drugs & Compounds for RNF227 Gene

No Compound Related Data Available

Transcripts for RNF227 Gene

mRNA/cDNA for RNF227 Gene

2 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNF227 Gene

No ASD Table

Relevant External Links for RNF227 Gene

GeneLoc Exon Structure for

Expression for RNF227 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RNF227

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNF227 Gene

Orthologs for RNF227 Gene

Evolution for RNF227 Gene

Gene Tree for RNF227 (if available)
Gene Tree for RNF227 (if available)

No data available for Orthologs for RNF227 Gene

Paralogs for RNF227 Gene

Paralogs for RNF227 Gene

genes like me logo Genes that share paralogs with RNF227: view

Variants for RNF227 Gene

Additional dbSNP identifiers (rs#s) for RNF227 Gene

Structural Variations from Database of Genomic Variants (DGV) for RNF227 Gene

Variant ID Type Subtype PubMed ID
nsv457660 CNV loss 19166990
nsv574333 CNV loss 21841781

Additional Variant Information for RNF227 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for RNF227 Gene

Disorders for RNF227 Gene

Additional Disease Information for RNF227

No disorders were found for RNF227 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF227 Gene

Publications for RNF227 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 3 4 54
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54

No data available for Mastermind for RNF227 Gene

Products for RNF227 Gene

Sources for RNF227 Gene