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Aliases for RNF225 Gene

Aliases for RNF225 Gene

  • Ring Finger Protein 225 2 3 5
  • RING Finger Protein 225 3

External Ids for RNF225 Gene

Summaries for RNF225 Gene

GeneCards Summary for RNF225 Gene

RNF225 (Ring Finger Protein 225) is a Protein Coding gene. An important paralog of this gene is RNF223.

Additional gene information for RNF225 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF225 Gene

Genomics for RNF225 Gene

GeneHancer (GH) Regulatory Elements for RNF225 Gene

Promoters and enhancers for RNF225 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J058394 Enhancer 1.3 Ensembl ENCODE dbSUPER 650.7 +0.5 492 3.4 PKNOX1 PTBP1 KLF17 MZF1 SIN3A KLF14 POLR2B GLIS2 SCRT2 RCOR1 GC19M058391 RNF225 RPS5 ZNF837 ZNF584 ZNF446 ENSG00000268912 ZNF814 LINC02560 GC19P058393
GH19J058392 Enhancer 0.5 dbSUPER 0.7 -2.6 -2579 0.5 POLR2A RBM22 ZBTB33 SUPT5H GC19P058393 ZNF837 LOC100419848 CENPBD1P1 GC19M058391 RNF225 RPS5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RNF225 on UCSC Golden Path with GeneCards custom track

Genomic Locations for RNF225 Gene

Genomic Locations for RNF225 Gene
chr19:58,395,657-58,398,954
(GRCh38/hg38)
Size:
3,298 bases
Orientation:
Plus strand
chr19:58,907,457-58,908,446
(GRCh37/hg19)
Size:
990 bases
Orientation:
Plus strand

Genomic View for RNF225 Gene

Genes around RNF225 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF225 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF225 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF225 Gene

Proteins for RNF225 Gene

  • Protein details for RNF225 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    M0QZC1-RN225_HUMAN
    Recommended name:
    RING finger protein 225
    Protein Accession:
    M0QZC1

    Protein attributes for RNF225 Gene

    Size:
    329 amino acids
    Molecular mass:
    34789 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RNF225 Gene

Post-translational modifications for RNF225 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RNF225 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF225 Gene

Domains & Families for RNF225 Gene

Gene Families for RNF225 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for RNF225 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNF225: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNF225 Gene

Function for RNF225 Gene

Gene Ontology (GO) - Molecular Function for RNF225 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with RNF225: view

Phenotypes for RNF225 Gene

genes like me logo Genes that share phenotypes with RNF225: view

Animal Model Products

CRISPR Products

miRNA for RNF225 Gene

miRTarBase miRNAs that target RNF225

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RNF225

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RNF225 Gene

Localization for RNF225 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF225 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for RNF225 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with RNF225: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for RNF225 Gene

Pathways & Interactions for RNF225 Gene

SuperPathways for RNF225 Gene

No Data Available

Interacting Proteins for RNF225 Gene

Gene Ontology (GO) - Biological Process for RNF225 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNF225 Gene

Drugs & Compounds for RNF225 Gene

No Compound Related Data Available

Transcripts for RNF225 Gene

mRNA/cDNA for RNF225 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RNF225

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNF225 Gene

No ASD Table

Relevant External Links for RNF225 Gene

GeneLoc Exon Structure for
RNF225
ECgene alternative splicing isoforms for
RNF225

Expression for RNF225 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNF225 Gene

NURSA nuclear receptor signaling pathways regulating expression of RNF225 Gene:

RNF225
genes like me logo Genes that share expression patterns with RNF225: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNF225 Gene

Orthologs for RNF225 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNF225 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia LOC100684457 33
  • 82.91 (n)
-- 34
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2310014L17Rik 34 33
  • 73.99 (n)
OneToOne
Rnf225 16
rat
(Rattus norvegicus)
Mammalia RGD1561909 33
  • 73.12 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487311 33
  • 44.31 (n)
zebrafish
(Danio rerio)
Actinopterygii rnf183 34
  • 18 (a)
OneToOne
Species where no ortholog for RNF225 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RNF225 Gene

ENSEMBL:
Gene Tree for RNF225 (if available)
TreeFam:
Gene Tree for RNF225 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for RNF225: view image

Paralogs for RNF225 Gene

Paralogs for RNF225 Gene

genes like me logo Genes that share paralogs with RNF225: view

Variants for RNF225 Gene

Sequence variations from dbSNP and Humsavar for RNF225 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000196076 -- 58,393,814(+) T/C upstream_transcript_variant
rs1000393656 -- 58,396,993(+) C/A/T coding_sequence_variant, stop_gained, synonymous_variant
rs1000832213 -- 58,395,798(+) C/G genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001032676 -- 58,395,984(+) A/G genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001974531 -- 58,395,372(+) G/A 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant

Additional Variant Information for RNF225 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNF225

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNF225 Gene

Disorders for RNF225 Gene

Additional Disease Information for RNF225

No disorders were found for RNF225 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF225 Gene

Publications for RNF225 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58

Products for RNF225 Gene

Sources for RNF225 Gene

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