Aliases for RNF225 Gene

Aliases for RNF225 Gene

  • Ring Finger Protein 225 2 3 5
  • RING Finger Protein 225 3 4

External Ids for RNF225 Gene

Summaries for RNF225 Gene

GeneCards Summary for RNF225 Gene

RNF225 (Ring Finger Protein 225) is a Protein Coding gene. An important paralog of this gene is RNF223.

Additional gene information for RNF225 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RNF225 Gene

Genomics for RNF225 Gene

GeneHancer (GH) Regulatory Elements for RNF225 Gene

Promoters and enhancers for RNF225 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J058394 Promoter/Enhancer 1.3 Ensembl ENCODE dbSUPER 500.7 +0.1 61 2.6 ZNF217 TCF12 POLR2G ZIC2 POLR2A KLF7 CTBP1 SIN3A KLF9 ZNF282 RNF225 ZNF417 ZNF134 TRIM28 ZNF446 ZNF274 ZNF550 ZNF773 ZSCAN22 ZNF324B
GH19J058395 Enhancer 0.3 Ensembl 500.7 -1.8 -1756 0.2 GLIS1 POLR2A MIR10394-001 RNF225 NONHSAG026724.2 RPS5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RNF225 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RNF225

Genomic Locations for RNF225 Gene

Genomic Locations for RNF225 Gene
chr19:58,395,657-58,398,954
(GRCh38/hg38)
Size:
3,298 bases
Orientation:
Plus strand
chr19:58,907,457-58,908,446
(GRCh37/hg19)
Size:
990 bases
Orientation:
Plus strand

Genomic View for RNF225 Gene

Genes around RNF225 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF225 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF225 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF225 Gene

Proteins for RNF225 Gene

  • Protein details for RNF225 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    M0QZC1-RN225_HUMAN
    Recommended name:
    RING finger protein 225
    Protein Accession:
    M0QZC1

    Protein attributes for RNF225 Gene

    Size:
    329 amino acids
    Molecular mass:
    34789 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RNF225 Gene

Post-translational modifications for RNF225 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RNF225 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF225 Gene

Domains & Families for RNF225 Gene

Gene Families for RNF225 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for RNF225 Gene

genes like me logo Genes that share domains with RNF225: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RNF225 Gene

Function for RNF225 Gene

Gene Ontology (GO) - Molecular Function for RNF225 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with RNF225: view

Phenotypes for RNF225 Gene

genes like me logo Genes that share phenotypes with RNF225: view

miRNA for RNF225 Gene

miRTarBase miRNAs that target RNF225

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RNF225

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RNF225 Gene

Localization for RNF225 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF225 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for RNF225 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with RNF225: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for RNF225 Gene

Pathways & Interactions for RNF225 Gene

PathCards logo

SuperPathways for RNF225 Gene

No Data Available

Interacting Proteins for RNF225 Gene

;

Gene Ontology (GO) - Biological Process for RNF225 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNF225 Gene

Drugs & Compounds for RNF225 Gene

No Compound Related Data Available

Transcripts for RNF225 Gene

mRNA/cDNA for RNF225 Gene

1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RNF225

Alternative Splicing Database (ASD) splice patterns (SP) for RNF225 Gene

No ASD Table

Relevant External Links for RNF225 Gene

GeneLoc Exon Structure for
RNF225

Expression for RNF225 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RNF225 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RNF225

genes like me logo Genes that share expression patterns with RNF225: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNF225 Gene

Orthologs for RNF225 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNF225 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia LOC100684457 30
  • 82.91 (n)
-- 31
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2310014L17Rik 31 30
  • 73.99 (n)
OneToOne
Rnf225 17
rat
(Rattus norvegicus)
Mammalia RGD1561909 30
  • 73.12 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487311 30
  • 44.31 (n)
zebrafish
(Danio rerio)
Actinopterygii rnf183 31
  • 18 (a)
OneToOne
Species where no ortholog for RNF225 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RNF225 Gene

ENSEMBL:
Gene Tree for RNF225 (if available)
TreeFam:
Gene Tree for RNF225 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for RNF225: view image

Paralogs for RNF225 Gene

Paralogs for RNF225 Gene

genes like me logo Genes that share paralogs with RNF225: view

Variants for RNF225 Gene

Additional dbSNP identifiers (rs#s) for RNF225 Gene

Structural Variations from Database of Genomic Variants (DGV) for RNF225 Gene

Variant ID Type Subtype PubMed ID
nsv515731 CNV gain+loss 19592680
nsv833887 CNV loss 17160897
nsv833888 CNV loss 17160897
nsv961256 CNV duplication 23825009

Additional Variant Information for RNF225 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNF225

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for RNF225 Gene

Disorders for RNF225 Gene

Additional Disease Information for RNF225

No disorders were found for RNF225 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF225 Gene

Publications for RNF225 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 54

Products for RNF225 Gene

Sources for RNF225 Gene