Aliases for RNF220 Gene
External Ids for RNF220 Gene
Previous HGNC Symbols for RNF220 Gene
Previous GeneCards Identifiers for RNF220 Gene
GeneCards Summary for RNF220 Gene
RNF220 (Ring Finger Protein 220) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin-protein transferase activity.
UniProtKB/Swiss-Prot Summary for RNF220 Gene
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).