Aliases for RNF17 Gene
External Ids for RNF17 Gene
Previous HGNC Symbols for RNF17 Gene
Previous GeneCards Identifiers for RNF17 Gene
This gene is similar to a mouse gene that encodes a testis-specific protein containing a RING finger domain. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, May 2010]
GeneCards Summary for RNF17 Gene
RNF17 (Ring Finger Protein 17) is a Protein Coding gene. Diseases associated with RNF17 include Seckel Syndrome 4 and Seckel Syndrome 5. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity, acting on ester bonds. An important paralog of this gene is TDRD6.
UniProtKB/Swiss-Prot for RNF17 Gene
Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity).