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RNF169 (Ring Finger Protein 169) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ligase activity and nucleosome binding. An important paralog of this gene is RNF168.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016740 | transferase activity | IEA | -- |
GO:0031491 | nucleosome binding | IDA | 22742833 |
GO:0046872 | metal ion binding | IEA | -- |
GO:0070530 | K63-linked polyubiquitin modification-dependent protein binding | IDA | 22492721 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,IDA | 22733822 |
GO:0005654 | nucleoplasm | IEA,IDA | 22492721 |
GO:0005730 | nucleolus | IDA | -- |
GO:0005829 | cytosol | IDA | -- |
GO:0016604 | nuclear body | IDA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006974 | cellular response to DNA damage stimulus | IMP | 22492721 |
GO:0016567 | protein ubiquitination | IEA | -- |
GO:2000780 | negative regulation of double-strand break repair | IMP | 22492721 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RNF169 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RNF169 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RNF169 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Rnf169 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Rnf169 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | RNF169 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | RNF169 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | RNF169 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | RNF169 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100493580 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | rnf169 30 31 |
|
OneToOne |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv209e214 | CNV | gain | 21293372 |
dgv5e197 | CNV | deletion | 19546169 |
dgv676n106 | CNV | deletion | 24896259 |
esv2305041 | CNV | deletion | 18987734 |
esv2484083 | CNV | deletion | 19546169 |
esv2669092 | CNV | deletion | 23128226 |
esv2744779 | CNV | deletion | 23290073 |
esv2759837 | CNV | gain | 17122850 |
esv34979 | CNV | gain | 17911159 |
esv3548008 | CNV | deletion | 23714750 |
esv3626846 | CNV | gain | 21293372 |
nsv1122644 | CNV | deletion | 24896259 |
nsv1124643 | CNV | duplication | 24896259 |
nsv1127209 | CNV | deletion | 24896259 |
nsv38718 | CNV | deletion | 16902084 |
nsv825994 | CNV | gain | 20364138 |
nsv8839 | CNV | gain | 18304495 |
nsv957195 | CNV | deletion | 24416366 |
No disorders were found for RNF169 Gene.